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Study finds HER2 irregularities in 14 different advanced solid tumors

The HER2 growth-factor gene is known to be over-active in breast and gastro-esophageal cancers. But now, irregularities in the genes's expression - among them mutations, amplifications, substitutions, and translocations - have been found in 14 different advanced solid tumors.

3 Jun 2013

Mount Sinai researchers present landmark studies at ASCO meeting

Icahn School of Medicine at Mount Sinai researchers will present several landmark studies at the 2013 American Society of Clinical Oncology meeting May 31-June 4, 2013 in Chicago, including data on the likelihood of spousal human papillomavirus oral infection, new gene signatures in melanoma, and issues with high readmission rates after cancer surgery.

3 Jun 2013

Researchers develop RNA aptamers that inhibit HCV replication

Treatments against hepatitis C virus have only been partially successful. A major problem is that antivirals generate drug resistance. Now Seong-Wook Lee of Dankook University, Yongin, Republic of Korea and his collaborators have developed agents that bind to the business end of a critical protein, disabling it so successfully that no resistance has arisen.

3 Jun 2013

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails.

1 Jun 2013

Study shows utility of cfDNA blood tests for breast cancer patients

Researchers from Chronix Biomedical and The University of Texas MD Anderson Cancer Center today announced that results from a pilot study demonstrating the utility of cell-free DNA (cfDNA) blood tests as a companion diagnostic for breast cancer patients are to be reported in a poster presentation titled "Modulation of breast cancer cell-free DNA with surgical resection" (Abstract #11060) at the American Society of Clinical Oncology Annual Meeting (ASCO 2013) being held from May 31 through June 4, 2013 in Chicago. The blood test detects cfDNA that is released into the blood stream by damaged and dying cancer cells.

1 Jun 2013

Nearly 2/3 of solid tumors carry at least one mutation that may be targeted by existing compound

Nearly two-thirds of solid tumors carry at least one mutation that may be targeted, or medicated, by an existing compound, according to new findings from researchers Fox Chase Cancer Center that will be presented at the 49th Annual Meeting of the American Society of Clinical Oncology on June 3.

1 Jun 2013

Circadian rhythms can boost body's ability to fight intestinal bacterial infections, say researchers

Circadian rhythms can boost the body's ability to fight intestinal bacterial infections, UC Irvine researchers have found.

1 Jun 2013

International researchers find how brain cancer cells survive and drive tumor growth

An international team of researchers - led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine - has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that control cellular metabolism.

1 Jun 2013

Plants to teach robots how to work together

John Innes Centre scientists will participate in new -2 million EU-funded research to programme more "intelligent" and adaptable robot swarms.

1 Jun 2013

Researchers target possible new weapon in fight against malaria

Researchers are targeting a possible new weapon in the fight against malaria, science that could also be applied in the fight against other devastating mosquito-borne illnesses, according to a Vanderbilt study published in PLOS ONE.

1 Jun 2013

Researchers determine precise chemical structure of HIV capsid

Researchers have determined the precise chemical structure of the HIV capsid, a protein shell that protects the virus's genetic material and is a key to its ability to infect and debilitate the human body's defense mechanism.

1 Jun 2013

Findings could potentially lead to new drug therapy for Cushing disease

Cushing disease is a life-threatening disorder most commonly triggered by tumors, often benign, in the pituitary glands, resulting in excess production of adrenocorticotrophic hormone.

1 Jun 2013

Study points to synergistic relationship between lead exposure and schizophrenia gene

Mice engineered with a human gene for schizophrenia and exposed to lead during early life exhibited behaviors and structural changes in their brains consistent with schizophrenia.

1 Jun 2013

Nanoparticle-based immunotherapy for cancer

The German Research Foundation has established a new Collaborative Research Center on "Nanodimensional polymer therapeutics for tumor therapy" (CRC 1066) at Johannes Gutenberg University Mainz and the Max Planck Institute for Polymer Research (MPI-P).

1 Jun 2013

New nanoparticle gene delivery method to prevent stenting procedure complications

Stent angioplasty saves lives, but there often are side effects and complications related to the procedure, such as arterial restenosis and thrombosis. In the June 2013 issue of The FASEB Journal, however, scientists report that they have discovered a new nanoparticle gene delivery method that may overcome current limitations of gene therapy vectors and prevent complications associated with the stenting procedure.

1 Jun 2013

Researchers uncover role of key protein linked to development of cancers

Virginia Commonwealth University researchers studying a key molecular player called Hsp70 that is responsible for protein homeostasis have uncovered how it binds together with another molecule responsible for intracellular energy transfer to enhance its overall activity and efficiency - details that have previously not been well understood.

1 Jun 2013

Medical Science News

Study finds HER2 irregularities in 14 different advanced solid tumors

Mount Sinai researchers present landmark studies at ASCO meeting

Researchers develop RNA aptamers that inhibit HCV replication

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Study shows utility of cfDNA blood tests for breast cancer patients

Nearly 2/3 of solid tumors carry at least one mutation that may be targeted by existing compound

Circadian rhythms can boost body's ability to fight intestinal bacterial infections, say researchers

International researchers find how brain cancer cells survive and drive tumor growth

Plants to teach robots how to work together

Researchers target possible new weapon in fight against malaria

Researchers determine precise chemical structure of HIV capsid

Findings could potentially lead to new drug therapy for Cushing disease

Study points to synergistic relationship between lead exposure and schizophrenia gene

Nanoparticle-based immunotherapy for cancer

New nanoparticle gene delivery method to prevent stenting procedure complications

Researchers uncover role of key protein linked to development of cancers

Omega-3 fatty acids may reduce inflammation associated with cardiovascular procedures

University of Strathclyde uses new imaging technique to track nanomedicines' effects on patients

Culture plays role in deciding what makes a mate attractive, says researcher

Be ready for the next generation of cancer treatments

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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