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LOX enzyme can create scarred microenvironment that enhances cancer spreading

What to fear most if faced by a cancer diagnosis is the spread of the cancer to other parts of the body. This process called metastasis accounts for over 90% of cancer patient deaths and therefore is a strong focus for cancer researchers.

28 Jan 2013

Alzheimer's Association, SNMMI publish appropriate use criteria for brain amyloid imaging with PET

Only recently has it become possible to create high-quality images of the brain plaques characteristic of Alzheimer's disease in living people through positron emission tomography (PET). Even so, questions remain about what can be learned from these PET images and which people should have this test.

28 Jan 2013

Counsyl, ARUP partner to expand pregnancy genetic test offering for prospective parents

Counsyl has partnered with ARUP Laboratories, a nonprofit enterprise of the University of Utah, to expand its pre-pregnancy and early pregnancy genetic test offering for prospective parents. ARUP's molecular genetic testing laboratory already provides a comprehensive set of testing options for a broad range of inherited disorders.

28 Jan 2013

UMDNJ-School of Osteopathic Medicine to develop blood test that can diagnose MCI

The Biomarker Discovery Center at the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine has been awarded a three-year, $799,800 grant from the Osteopathic Heritage Foundation to develop a blood test that can diagnose mild cognitive impairment (MCI) caused by early-stage Alzheimer's disease.

28 Jan 2013

Carmenta acquires option to license Stanford technology for preeclampsia diagnostic test

Carmenta Bioscience, Inc., a privately held medical technology company focused on maternal and fetal health, today announced it has acquired the option for a worldwide, exclusive license from Stanford University to develop a set of tests enabling physicians to better diagnose and predict preeclampsia.

28 Jan 2013

Endo Pharmaceuticals, GVK BIO enter research collaboration agreement

GVK Biosciences (GVK BIO), Asia's leading drug discovery research and development CRO announced today that it has entered into a collaboration agreement with U.S. based Endo Pharmaceuticals focused on discovering novel small molecules targeting an exciting protein.

28 Jan 2013

Research into anesthesia neurotoxicity in the developing brain

Several studies have found evidence that children who undergo repeated surgical operations with general anesthesia before the age of 4 may be at an increased risk for learning disabilities.

28 Jan 2013

Certain forms of abuse negatively influence women cancer patients' quality of life

A new study by University of Kentucky researchers shows evidence that certain forms of abuse negatively influence women cancer patients' quality of life.

28 Jan 2013

Study sheds new light on why certain people are more likely to suffer from RA

University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis - paving the way to explore new treatments for both arthritis and other autoimmune diseases.

28 Jan 2013

AstraZeneca, Orexo partner on OX-CLI preclinical program to treat respiratory diseases

Orexo AB announced today that the company has entered into an agreement with AstraZeneca regarding OX-CLI, a preclinical program for a potential novel treatment of respiratory diseases.

28 Jan 2013

TSRI scientists to identify, test and develop drug candidates for several neurodegenerative disorders

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $1.2 million from the U.S. National Institute of General Medical Sciences of the National Institutes of Health to identify, test and develop a series of drug candidates for a number of diseases, including rheumatoid arthritis, heart disease and several neurodegenerative disorders.

28 Jan 2013

IRHOM2-targeted drugs can effectively treat patients with rheumatoid arthritis

Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis (RA), a protein known as IRHOM2. The finding could provide an effective and potentially less toxic alternative therapy to tumor necrosis factor-alpha blockers (TNF-blockers), the mainstay of treatment for rheumatoid arthritis, and could help patients who do not respond to this treatment. Efforts to develop drugs that hone in on this new target are underway.

28 Jan 2013

Research reveals the mechanism of epigenetic reprogramming

New research reveals a potential way for how parents' experiences could be passed to their offspring's genes.

28 Jan 2013

Telomerase gene mutation immortalizes deadly skin cancer

About ten percent of all cases of malignant melanoma are familial cases. The genome of affected families tells scientists a lot about how the disease develops. Prof. Dr. Rajiv Kumar of the German Cancer Research Center together with Prof. Dr. Dirk Schadendorf from Essen University Hospital studied a family where 14 family members were affected by malignant melanoma.

28 Jan 2013

Study shows how GATA3 protein acts downstream biochemically to prevent breast cancer metastasis

The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries point to possible targets for therapy.

28 Jan 2013

Behavioral stress accelerates prostate cancer development in mice

Prostate cancer patients have increased levels of stress and anxiety; however, several recent studies have found that men who take drugs that interfere with the stress hormone adrenaline have a lower incidence of prostate cancer.

28 Jan 2013

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant form of the p53 gene, the major tumor suppressor in humans, which is generally found mutated in over 50% of all type of human cancers.

27 Jan 2013

Medical Science News

LOX enzyme can create scarred microenvironment that enhances cancer spreading

Alzheimer's Association, SNMMI publish appropriate use criteria for brain amyloid imaging with PET

Counsyl, ARUP partner to expand pregnancy genetic test offering for prospective parents

UMDNJ-School of Osteopathic Medicine to develop blood test that can diagnose MCI

Carmenta acquires option to license Stanford technology for preeclampsia diagnostic test

Endo Pharmaceuticals, GVK BIO enter research collaboration agreement

Research into anesthesia neurotoxicity in the developing brain

Certain forms of abuse negatively influence women cancer patients' quality of life

Study sheds new light on why certain people are more likely to suffer from RA

AstraZeneca, Orexo partner on OX-CLI preclinical program to treat respiratory diseases

TSRI scientists to identify, test and develop drug candidates for several neurodegenerative disorders

IRHOM2-targeted drugs can effectively treat patients with rheumatoid arthritis

Research reveals the mechanism of epigenetic reprogramming

Telomerase gene mutation immortalizes deadly skin cancer

Study shows how GATA3 protein acts downstream biochemically to prevent breast cancer metastasis

Behavioral stress accelerates prostate cancer development in mice

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

Researchers identify cancer-associated mutations

Genome sequencing data gives important clues on cancer

New method allows controlled release of drugs; could help develop targeted treatments

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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