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Combination of blood test and whole-genome sequencing technology could screen cancers

Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.

29 Nov 2012

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.

29 Nov 2012

Majority of parents with autistic child show interest in having genetic tests

The vast majority (80 percent) of parents with at least one child with Autism Spectrum Disorder (ASD) would pursue genetic testing if a test were available that could identify risk in a younger sibling, citing the desire for earlier identification of children at risk, earlier evaluation and intervention, closer monitoring and lessened anxiety.

29 Nov 2012

Yale and Mainz University Medical Center to extend collaboration

The University Medical Center at Johannes Gutenberg University Mainz, Germany and the renowned School of Medicine at Yale University, USA have agreed upon a future collaboration. This strategic partnership promises to provide an innovative stimulus for the Research Unit Translational Neurosciences at the Mainz University Medical Center. The resulting regular exchange will benefit both basic research and the training of young researchers.

29 Nov 2012

Children of low socioeconomic status work harder to filter out irrelevant environmental information

Children of low socioeconomic status work harder to filter out irrelevant environmental information than those from a high-income background because of learned differences in what they pay attention to, according to new research published in the open access journal Frontiers in Human Neuroscience.

29 Nov 2012

New antifungal drugs could be developed based on substance bacteria use to decompose mushrooms

Soft rot diseases cause a great deal of damage in agriculture, and turn fruits, vegetables, and mushrooms to mush. By using imaging mass spectrometry together with genetic and bioinformatic techniques (genome mining), German researchers have now discovered the substance the bacteria use to decompose mushrooms.

29 Nov 2012

Microglia might play a key role in protecting brain from Alzheimer's

A new experimental study carried out in mice shows that microglia, immune cells of the brain, might play a key role in protecting the brain from Alzheimer's disease (AD).

29 Nov 2012

New paper describes MCUR1 protein and its function

Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell's energy storehouse - the mitochondria -- is important for understanding a cell's normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

29 Nov 2012

Answers to the questions of stem cells

Next week, more than 1,200 people from 25 countries are expected to attend the 8th Annual World Stem Cell Summit in West Palm Beach, Fla., a gathering co-sponsored by Mayo Clinic. As those close to the science explore potential stem cell applications, many patients have questions about what stem cells are and how they are being used. Timothy Nelson, M.D., Ph.D., director of Mayo Clinic's Regenerative Medicine Consult Service, answers some of the most commonly asked questions about stem cells.

29 Nov 2012

Vacuum-compatible Pilatus X-ray detector can now track nanoparticles

Microvesicles are smallest cell elements which are present in all body fluids and are different, depending on whether a person is healthy or sick. This could contribute to detecting numerous diseases, such as, e.g., carcinomas, at an early stage, and to treating them more efficiently. The problem is that the diameter of the relevant microvesicles generally lies below 100 nm, which makes them technically detectable, but their exact size and concentration hardly possible to determine. A new device is now to provide the metrological basis for these promising biomarkers.

29 Nov 2012

Reduction in myelin production may also play a role in development of mental illness

Reduced production of myelin, a type of protective nerve fiber that is lost in diseases like multiple sclerosis, may also play a role in the development of mental illness, according to researchers at the Graduate School of Biomedical Sciences at Mount Sinai School of Medicine. The study is published in the journal Nature Neuroscience.

29 Nov 2012

microRNA-223 molecule plays a surprising role in protecting brain cells from stroke effects

A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report. The molecule, microRNA-223, affects how cells respond to the temporary loss of blood supply brought on by stroke - and thus the cells' likelihood of suffering permanent damage.

29 Nov 2012

Disabling ItpkB enzyme improves function of Natural Killer cells

Researchers at The Scripps Research Institute (TRSI) are fueling the future of cancer treatment by improving a powerful tool in disease defense: the body's immune system. By revealing a novel but widespread cell signaling process, the scientists may have found a way to manipulate an important component of the immune system into more effectively fighting disease.

29 Nov 2012

Scientists discover synchronous brain activity between two guitarists

Researchers from the Max Planck Institute for Human Development in Berlin have shown that synchronization emerges between brains when making music together, and even when musicians play different voices. In a study published November 29th in Frontiers in Neuroscience, Johanna S-nger and her team used electrodes to record the brain waves of guitarists while they played different voices of the same duet.

29 Nov 2012

Study identifies metabolic factors related to bread's beneficial effects on cardiovascular health

According to a study, daily bread consumption, especially wholemeal bread, can prevent cardiovascular disease. The study has been led by the professor Rafael Llorach, Ramon y Cajal researcher from the Department of Nutrition and Bromatology at the Faculty of Pharmacy and from the Food and Nutrition Torribera campus of the University of Barcelona.

29 Nov 2012

IL17RC-mediated immune responses can be crucial in causing AMD

Changes in how genes in the immune system function may result in age-related macular degeneration (AMD), the leading cause of visual impairment in older adults, based on preliminary research conducted by National Institutes of Health (NIH) investigators.

29 Nov 2012

Trovagene develops first molecular diagnostic test to detect KRAS mutations from urine samples

Trovagene, Inc. today announced successful development of its first molecular diagnostic test capable of detecting KRAS mutations from a urine specimen. Transfer of the transrenal KRAS test to the company's CLIA lab is expected to be completed in December 2012 with commercial availability expected in January 2013.

28 Nov 2012

Engineered ICCs can improve pancreatic islet transplantation and cure diabetes mellitus

A study published in the current issue of Cell Transplantation, now freely available on-line, reports that a team of researchers in South Korea have successfully engineered islet cell clusters (ICCs) that will improve pancreatic islet transplantation and offer promise for curing diabetes mellitus.

28 Nov 2012

Injecting Wnt7a protein could prevent Duchenne muscular dystrophy

Scientists have discovered that injecting a novel human protein into muscle affected by Duchenne muscular dystrophy significantly increases its size and strength, findings that could lead to a therapy akin to the use of insulin by diabetics.

28 Nov 2012

Hebrew University of Jerusalem develops sonar vision device for congenitally blind people

A "sonar vision" system that enables people who are blind from birth to perceive the shape of a face, a house or even words and letters, is being developed by a team at the Hebrew University of Jerusalem.

28 Nov 2012

Medical Science News

Combination of blood test and whole-genome sequencing technology could screen cancers

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

Majority of parents with autistic child show interest in having genetic tests

Yale and Mainz University Medical Center to extend collaboration

Children of low socioeconomic status work harder to filter out irrelevant environmental information

New antifungal drugs could be developed based on substance bacteria use to decompose mushrooms

Microglia might play a key role in protecting brain from Alzheimer's

New paper describes MCUR1 protein and its function

Answers to the questions of stem cells

Vacuum-compatible Pilatus X-ray detector can now track nanoparticles

Reduction in myelin production may also play a role in development of mental illness

microRNA-223 molecule plays a surprising role in protecting brain cells from stroke effects

Disabling ItpkB enzyme improves function of Natural Killer cells

Scientists discover synchronous brain activity between two guitarists

Study identifies metabolic factors related to bread's beneficial effects on cardiovascular health

IL17RC-mediated immune responses can be crucial in causing AMD

Trovagene develops first molecular diagnostic test to detect KRAS mutations from urine samples

Engineered ICCs can improve pancreatic islet transplantation and cure diabetes mellitus

Injecting Wnt7a protein could prevent Duchenne muscular dystrophy

Hebrew University of Jerusalem develops sonar vision device for congenitally blind people

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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