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Women more likely to have gray matter atrophy prior to Alzheimer's diagnosis than men

All patients with Alzheimer's disease (AD) lose brain cells, which leads to a shrinking, or atrophy, of the brain. But the pattern of gray matter loss is significantly different in men and women, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

$Study identifies fractional anisotropy as predictor of brain damage after TBI$

Study identifies fractional anisotropy as predictor of brain damage after TBI

Using a special magnetic resonance imaging (MRI) technique to image patients with mild traumatic brain injury (MTBI), researchers have identified a biomarker that may predict which patients will do well over the long term, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

People with Parkinson's benefit from exercise programs on stationary bicycles

People with Parkinson's disease benefit from exercise programs on stationary bicycles, with the greatest effect for those who pedal faster, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Active lifestyle helps preserve brain structure and could reduce burden of dementia, Alzheimer's

An active lifestyle helps preserve gray matter in the brains of older adults and could reduce the burden of dementia and Alzheimer's disease (AD), according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Alcohol exposure during fetal development alters brain structure and metabolism in children

Children exposed to alcohol during fetal development exhibit changes in brain structure and metabolism that are visible using various imaging techniques, according to a new study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Study shows how MCUR1 protein helps regulate movement of calcium into mitochondria

A team of scientists from Temple University School of Medicine and the University of Pennsylvania has moved another step closer to solving a decades-long mystery of how the all-important flow of calcium into the cell's power source, the mitochondria, is controlled.

26 Nov 2012

mRNA vaccines offer protection against influenza A virus infections in various animal models

CureVac GmbH, a clinical stage biopharmaceutical company developing a new class of therapies and vaccines based on mRNA, and the German Federal Research Institute for Animal Health, Friedrich-Loeffler-Institute (FLI), Germany, today announced that mRNA vaccines (RNActive) based on the company's RNA technology platform have the potential to provide effective protection against infectious diseases.

26 Nov 2012

Turning off particular cytokines reduces Alzheimer's typical amyloid-- deposits in mice

Alzheimer's disease is one of the most common causes of dementia. In Germany and Switzerland alone, around 1.5 million people are affected, and forecasts predict a doubling of the number of patients worldwide within the next 20 years. The accumulation of particular abnormal proteins, including amyloid-- (Aβ) among others, in patients' brains plays a central role in this disease.

26 Nov 2012

Researchers trace specific paths of chandelier cells during development into the cerebral cortex

The cerebral cortex of the human brain has been called "the crowning achievement of evolution." Ironically, it is so complex that even our greatest minds and most sophisticated science are only now beginning to understand how it organizes itself in early development, and how its many cell types function together as circuits.

23 Nov 2012

Research reveals surprisingly complex protein-coding capacity of human cytomegalovirus

New findings reveal the surprisingly complex protein-coding capacity of the human cytomegalovirus, or HCMV, and provide the first steps toward understanding how the virus manipulates human cells during infection. The genome of the HCMV was first sequenced over 20 years ago, but researchers have now investigated the proteome-the complete set of expressed proteins-of this common pathogen as well.

23 Nov 2012

Major advance in understanding how flu viruses replicate within infected cells

Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to "see" one of influenza's essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus's vulnerabilities that are sure to be of interest to drug developers.

23 Nov 2012

Researchers characterize novel lysosomal PQ protein linked to cystinosis

Researchers at the Université Paris Descartes/CNRS and the Université libre de Bruxelles have made a major breakthrough in the study of cystinosis, a genetic disease that can lead to serious disorders, notably fatal kidney failure.

23 Nov 2012

Advances in genomic techniques help understand cancer at cellular and molecular level

Cancer is a complex disease and only thanks to advances in genomic techniques have researchers begun to understand, at a cellular and molecular level, the mechanisms which are disrupted in cancer cells. This knowledge is a key prerequisite for developing effective treatment strategies.

23 Nov 2012

New research provides unprecedented clarity to aging process

For the first time, scientists at Fred Hutchinson Cancer Research Center have defined key events that take place early in the process of cellular aging.

23 Nov 2012

Researchers create 3D map of rod sensory cilium architecture affected by mutation

Using a new technique called cryo-electron tomography, two research teams at Baylor College of Medicine (www.bcm.edu) have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.

23 Nov 2012

Study to discover exactly how intravenous immune globulin treatments work

Immune globulin replacement began decades ago as a treatment for patients who could not make their own protective antibodies, but has proven to have much broader benefits than originally expected.

22 Nov 2012

Breakthrough in heart research

Breakthrough in heart research: The research team from Professor Katja Schenke-Layland of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs).

22 Nov 2012

TGF-betaR inhibitors may counter drug resistance in cancer patients with MED12 mutations

Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published by Cell Press November 21st in the journal Cell.

22 Nov 2012

Coronary arteries largely arise from cells of the endocardium

During embryonic development, the all-important coronary arteries arise from cells previously considered incapable of producing them, according to scientists at Albert Einstein College of Medicine of Yeshiva University.

22 Nov 2012

Researchers define structure of Cdc13 protein in yeast

Chromosomes - long, linear DNA molecules - are capped at their ends with special DNA structures called telomeres and an assortment of proteins, which together act as a protective sheath. Telomeres are maintained through the interactions between an enzyme, telomerase, and several accessory proteins. Researchers at The Wistar Institute have defined the structure of one of these critical proteins in yeast.

22 Nov 2012

Medical Science News

Women more likely to have gray matter atrophy prior to Alzheimer's diagnosis than men

Study identifies fractional anisotropy as predictor of brain damage after TBI

People with Parkinson's benefit from exercise programs on stationary bicycles

Active lifestyle helps preserve brain structure and could reduce burden of dementia, Alzheimer's

Alcohol exposure during fetal development alters brain structure and metabolism in children

Study shows how MCUR1 protein helps regulate movement of calcium into mitochondria

mRNA vaccines offer protection against influenza A virus infections in various animal models

Turning off particular cytokines reduces Alzheimer's typical amyloid-- deposits in mice

Researchers trace specific paths of chandelier cells during development into the cerebral cortex

Research reveals surprisingly complex protein-coding capacity of human cytomegalovirus

Major advance in understanding how flu viruses replicate within infected cells

Researchers characterize novel lysosomal PQ protein linked to cystinosis

Advances in genomic techniques help understand cancer at cellular and molecular level

New research provides unprecedented clarity to aging process

Researchers create 3D map of rod sensory cilium architecture affected by mutation

Study to discover exactly how intravenous immune globulin treatments work

Breakthrough in heart research

TGF-betaR inhibitors may counter drug resistance in cancer patients with MED12 mutations

Coronary arteries largely arise from cells of the endocardium

Researchers define structure of Cdc13 protein in yeast

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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