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Advanced genetics technologies may help predict patient outcomes in people with ALL

New evidence suggests that using advanced genetics technologies to monitor for remaining cancer cells after treatment may soon become an effective tool to inform treatment decisions and ultimately predict patient outcomes for patients with a particularly aggressive form of acute lymphocytic leukemia (ALL).

10 Jul 2013

UBC researchers develop vaccine to halt spread of West Nile Virus in birds

University of British Columbia researchers have developed a vaccine that may halt the spread of West Nile Virus among common and endangered bird species.

10 Jul 2013

Research finding may offer novel path for cancer drug design

Genetic mutations aren't the only thing that can keep a protein called PTEN from doing its tumor-suppressing job. Johns Hopkins researchers have now discovered that four small chemical tags attached (reversibly) to the protein's tail can have the same effect, and they say their finding may offer a novel path for drug design to keep PTEN working.

10 Jul 2013

Study confirms role of MAPK mutations in pilocytic astrocytomas

Brain cancer is the primary cause of cancer mortality in children. Even in cases when the cancer is cured, young patients suffer from the stress of a treatment that can be harmful to the developing brain. In a search for new target structures that would create more gentle treatments, cancer researchers are systematically analyzing all alterations in the genetic material of these tumors.

10 Jul 2013

New approach delivers RNA drugs to silence malfunctioning genes

Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference.

10 Jul 2013

RUB chemists track interaction of enkephalin messengers with opioid receptor

"Pain begone!" In order to send out this signal, the human body produces tiny messenger molecules that dock to certain receptors. Using traditional biochemical methods, this interaction between the messengers, so-called enkephalins, and opioid receptors is very difficult to study.

10 Jul 2013

Rising unemployment rates stop upward trend of fertility in European countries

The largest effect was seen in young adults. Europeans under the age of 25 have especially refrained from having children in the face of rising unemployment rates. The drop of children per woman was strongest for first births. That means, over the last decade young Europeans have particularly postponed family formation.

10 Jul 2013

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

In the constant cross talk between our brain and our gut, two gut hormones are already known to tell the brain when we have had enough to eat. New research suggests that boosting levels of these hormones simultaneously may be an effective new weapon in the fight against obesity.

10 Jul 2013

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.

10 Jul 2013

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

Amyotrophic Lateral Sclerosis (ALS) is a devastating motor neuron disease that rapidly atrophies the muscles, leading to complete paralysis. Despite its high profile - established when it afflicted the New York Yankees' Lou Gehrig - ALS remains a disease that scientists are unable to predict, prevent, or cure.

10 Jul 2013

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

FORMA Therapeutics and Cancer Research Technology, Ltd., the commercialization company of Cancer Research UK, announced today a bold research initiative to discover innovative tools, technologies and therapeutic drug candidates against a variety of protein homeostasis regulators called, deubiquitinating enzymes.

9 Jul 2013

NeuRA study: Orbitofrontal cortex plays key role in linking emotion, memories in FTD patients

A study by researchers at Neuroscience Research Australia (NeuRA) is the first to demonstrate that patients with frontotemporal dementia (FTD) lose the emotional content/colour of their memories. These findings explain why FTD patients may not vividly remember an emotionally charged event like a wedding or funeral.

9 Jul 2013

Key metabolites in blood could provide clues to long-term overall health and ageing

Scientists have found that key metabolites in blood - chemical 'fingerprints' left behind as a result of early molecular changes before birth or in infancy - could provide clues to a person's long-term overall health and rate of ageing in later life.

9 Jul 2013

Physicians have new resource for managing disease in patients with early-stage breast cancer

Physicians have a new resource for managing disease in patients with early-stage breast cancer. Patients diagnosed with ductal carcinoma in situ -- cancer that has not left the breast ducts -- now have the benefit of a multi-gene analysis that considers gene patterns to individualize therapy and determine the chance for recurrence, potentially sparing the patient additional therapy.

9 Jul 2013

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

9 Jul 2013

Altruism is important, but financial compensation a convincing reason for egg donation in some countries

Egg donation is now one of the major reasons why couples travel abroad for fertility treatment. Because this growing trend may circumvent regulations at home or raise concerns about financial inducement, it has also become one of the most controversial.

9 Jul 2013

Researchers discover potential biomarkers that track progression of neurodegenerative disease

A hallmark of neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's is that by the time symptoms appear, significant brain damage has already occurred-and currently there are no treatments that can reverse it.

9 Jul 2013

Macrophages play essential role in production of progesterone hormone

New research from the University of Adelaide shows for the first time that immune cells known as macrophages are critical to fertility by creating a healthy hormone environment in the uterus.

9 Jul 2013

Oklahoma Norman campus researchers receive OCAST grants for health research projects

Four University of Oklahoma Norman campus researchers were awarded OCAST grants for health research projects on subjects that range from the development of bone grafts using adult stem cells to the identification of genes to block parasite development in mosquitoes to new drug development pipelines to improvements in limb movement.

9 Jul 2013

MerTK inhibition in leukocytes decreases tumor growth and metastasiss

The tyrosine kinase MerTK plays a prominent role in the body's immune response. MerTK signaling helps "calm" the body's first line of immunity, the macrophage, while it performs the routine duties - clearing cells that die and healing damaged tissue.

9 Jul 2013

Medical Science News

Advanced genetics technologies may help predict patient outcomes in people with ALL

UBC researchers develop vaccine to halt spread of West Nile Virus in birds

Research finding may offer novel path for cancer drug design

Study confirms role of MAPK mutations in pilocytic astrocytomas

New approach delivers RNA drugs to silence malfunctioning genes

RUB chemists track interaction of enkephalin messengers with opioid receptor

Rising unemployment rates stop upward trend of fertility in European countries

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

NeuRA study: Orbitofrontal cortex plays key role in linking emotion, memories in FTD patients

Key metabolites in blood could provide clues to long-term overall health and ageing

Physicians have new resource for managing disease in patients with early-stage breast cancer

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

Altruism is important, but financial compensation a convincing reason for egg donation in some countries

Researchers discover potential biomarkers that track progression of neurodegenerative disease

Macrophages play essential role in production of progesterone hormone

Oklahoma Norman campus researchers receive OCAST grants for health research projects

MerTK inhibition in leukocytes decreases tumor growth and metastasiss

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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