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Study provides new information on impact of cognitive impairments on MS

Researchers at Trinity College Dublin in collaboration with colleagues in the Department of Neurology at St Vincent's University Hospital and University College Dublin have recently reported new insights into cognitive changes in multiple sclerosis, using newly developed signal processing methods.

11 Oct 2012

Testosterone fosters social behavior in men

The hormone testosterone stands for typically male attributes - it fosters the forming of the sexual characteristics, increases libido and muscle building. Women also have this sex hormone, but to a much lesser extent.

11 Oct 2012

Researchers identify astrocytes as new target for Alzheimer's

Alzheimer's disease is a severe neurodegenerative disease that affects 45% of people over 85 years of age. The research teams of Prof. Jin-Moo Lee at Washington University in Saint Louis, USA, and Prof. Milos Pekny at Sahlgrenska Academy in Gothenburg, Sweden, have identified astrocytes as a novel target for the development of future treatment strategies. The results have just been published in the FASEB Journal.

10 Oct 2012

UCSF project to explore mystery behind advanced prostate cancer

Many men survive prostate cancer, but thousands of others -- whose cancer spreads -- inevitably develop resistance to even the most promising treatments, leaving them with few medical options and a dwindling span of life.

10 Oct 2012

Spanish and British scientists design new blood test to identify aggressive prostate cancer

Scientists from the Spanish National Cancer Research Centre (CNIO) in Madrid, along with British colleagues from the Institute for Cancer Research (ICR) and the Royal Marsden NHS Foundation Trust, have developed a test that studies genetic patterns in blood cells to detect advanced-stage prostate cancer.

10 Oct 2012

U-M researchers to better understand HIV virus on a molecular level

A new $21-million grant will help researchers at the University of Michigan Health System better understand the HIV virus on a molecular level, potentially paving the way for new treatment approaches to AIDS and other diseases.

10 Oct 2012

Scientists discover mechanism used by A20 protein to combat inflammation

Scientists affiliated with VIB and UGent have discovered a mechanism used by the protein A20 to combat inflammation. This could be a very important point of focus in the search for a treatment for autoimmune diseases such as Rheumatoid Arthritis, in which the patient suffers from chronic, uncontrolled inflammation.

10 Oct 2012

Dieting, exercise can spur HDL cholesterol production in type 2 diabetics

With a little exercise and dieting, overweight people with type 2 diabetes can still train their fat cells to produce a hormone believed to spur HDL cholesterol production, report medical researchers from The Methodist Hospital and eight other institutions in an upcoming issue of the Journal of Lipid Research.

10 Oct 2012

Roitt's Essential Immunology receives BMA Book of the Year Award

John Wiley & Sons, Inc., today announced that Roitt's Essential Immunology, 12th Edition, has won the prestigious British Medical Association (BMA) Book of the Year Award.

10 Oct 2012

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

Plasma levels of proneurotensin are associated with the development of diabetes, cardiovascular disease, cardiovascular and total mortality, and breast cancer in women during long-term follow-up, according to a study in the October 10 issue of JAMA.

10 Oct 2012

PARP-1 plays a major role in controlling AR function in prostate cancer patients

A newly discovered function of PARP-1 could be the key to more effective therapeutics to treat advanced prostate cancer patients, a recent preclinical study published in Cancer Discovery by Jefferson's Kimmel Cancer Center researchers suggests.

10 Oct 2012

High-fat Western diet could lead to development of atherosclerosis

Columbia University Medical Center (CUMC) researchers have found that a diet high in saturated fat raises levels of endothelial lipase (EL), an enzyme associated with the development of atherosclerosis, and, conversely, that a diet high in omega-3 polyunsaturated fat lowers levels of this enzyme.

10 Oct 2012

Researchers identify two new small 'chaperone' molecules that may treat Schindler/Kanzaki disease

University of Massachusetts Amherst researchers, experts in revealing molecular structure by X-ray crystallography, have identified two new small "chaperone" molecules that may be useful in treating the inherited metabolic disorder known as Schindler/Kanzaki disease.

10 Oct 2012

Chemotherapy plus immunotherapy can enhance anti-tumor effects in patients with advanced cancer

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Tianjin Medical University Cancer Institute and Hospital in China have discovered that combining chemotherapy drugs and immunotherapy cancer vaccines results in an enhanced anti-tumor effect.

10 Oct 2012

New screening method may lead to more efficient RNA drug development

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new method of screening more than three million combinations of interactions between RNA and small molecules to identify the best targets on RNA as well as the most promising potential drug compounds.

10 Oct 2012

Modifying factors may be responsible for non-diabetic kidney disease in African-Americans

The high rate of non-diabetic kidney disease in African-Americans is strongly associated with variations in a particular gene. Yet, not everyone who inherits these variations develops the disease.

10 Oct 2012

Recovering Treg cells in pancreatic lymph nodes may restore insulin production in type I diabetics

The key to restoring production of insulin in type I diabetic patients, previously known as juvenile diabetes, may be in recovering the population of protective cells known T regulatory cells in the lymph nodes at the "gates" of the pancreas, a new preclinical study published online October 8 in Cellular & Molecular Immunology by researchers in the Department of Bioscience Technologies at Thomas Jefferson University suggests.

10 Oct 2012

Researchers discover mechanism by which magnesium reduces cytokine production

Magnesium sulfate is given to many pregnant women to treat preterm labor and preeclampsia and was recently shown to prevent cerebral palsy; however little is known about how it works. Researchers at Case Western Reserve University School of Medicine recently discovered the mechanism by which magnesium reduces the production of cytokines.

10 Oct 2012

Salivary-biomarker approach can identify individuals at future risk of PTSD, depression

Each year, more than a million Americans are at-risk of developing serious mental health problems after experiencing a terrifying event or serious physical injury. Once manifested, these psychiatric illnesses, such as post-traumatic stress disorder and depression, can be extremely crippling and difficult to treat and are a leading cause of disability in civilian, military and minority populations.

10 Oct 2012

Chronic kidney disease changes the composition of intestinal bacterial microbes

Chronic kidney disease changes the composition of intestinal bacterial microbes that normally play a crucial role in staving off disease-causing pathogens and maintaining micronutrient balance, according to UC Irvine researchers.

10 Oct 2012

Medical Science News

Study provides new information on impact of cognitive impairments on MS

Testosterone fosters social behavior in men

Researchers identify astrocytes as new target for Alzheimer's

UCSF project to explore mystery behind advanced prostate cancer

Spanish and British scientists design new blood test to identify aggressive prostate cancer

U-M researchers to better understand HIV virus on a molecular level

Scientists discover mechanism used by A20 protein to combat inflammation

Dieting, exercise can spur HDL cholesterol production in type 2 diabetics

Roitt's Essential Immunology receives BMA Book of the Year Award

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

PARP-1 plays a major role in controlling AR function in prostate cancer patients

High-fat Western diet could lead to development of atherosclerosis

Researchers identify two new small 'chaperone' molecules that may treat Schindler/Kanzaki disease

Chemotherapy plus immunotherapy can enhance anti-tumor effects in patients with advanced cancer

New screening method may lead to more efficient RNA drug development

Modifying factors may be responsible for non-diabetic kidney disease in African-Americans

Recovering Treg cells in pancreatic lymph nodes may restore insulin production in type I diabetics

Researchers discover mechanism by which magnesium reduces cytokine production

Salivary-biomarker approach can identify individuals at future risk of PTSD, depression

Chronic kidney disease changes the composition of intestinal bacterial microbes

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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