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MYCN amplification can serve as a favorable prognostic indicator for neuroblastoma

Neuroblastoma, a malignant tumor that primarily affects infants and young children, is a leading cause of death for children with cancer. When amplification of the MYCN oncogene is found in the tumor, it usually indicates an aggressive tumor with rapid progression of the disease and a poor outcome. Thus MYCN amplification has come to be used as a prognostic indicator.

12 Aug 2011

New measurement technologies provide scientists more complete look at neurological activity

In 1991, Carl Lewis was both the fastest man on earth and a profound long jumper, perhaps the greatest track-and-field star of all time in the prime of his career. On June 14th of that year, however, Carl Lewis was human. Leroy Burrell blazed through the 100-meters, besting him by a razor-thin margin of three-hundredths of a second. In the time it takes the shutter to capture a single frame of video, Lewis's three-year-old world record was gone.

12 Aug 2011

NSAIDs like ibuprofen slow the spread of breast cancers

Published online on Aug. 7, 2011, the journal Nature Medicine reports that non-steroidal anti-inflammatory drugs including ibuprofen reduce the severity of postpartum breast cancers in animal models.

12 Aug 2011

La Jolla Institute's new RNAi Center to focus on genetics behind myriad diseases

A major Center that will propel scientific efforts to pinpoint the specific genes involved in causing immune diseases, cancer and other diseases will be opened today at the La Jolla Institute for Allergy & Immunology.

12 Aug 2011

Female sex hormone oestrogen could fight against cardiovascular disease

The sex hormone oestrogen could help protect women from cardiovascular disease by keeping the body's immune system in check, new research from Queen Mary, University of London has revealed.

12 Aug 2011

Medical College of Wisconsin to establish National Center for Systems Biology

The Medical College of Wisconsin has received a five-year, $13 million grant to establish a National Center for Systems Biology.

12 Aug 2011

Researchers discover key reason why pyrazinamide shortens duration of TB therapy

Pyrazinamide has been used in combination with other drugs as a first-line treatment for people with tuberculosis (TB) since the 1950s, but exactly how the drug works has not been well understood.

12 Aug 2011

NPL scientists mimick the ways viruses infect human cells and deliver genetic material

Scientists at the National Physical Laboratory (NPL) have mimicked the ways viruses infect human cells and deliver their genetic material. The research hopes to apply the approach to gene therapy - a therapeutic strategy to correct defective genes such as those that cause cancer.

12 Aug 2011

Study links low vitamin D with early menstruation in young girls

A study links low vitamin D in young girls with early menstruation, which is a risk factor for a host of health problems for teen girls as well as women later in life.

12 Aug 2011

Single engineered protein blocks two related angiogenic receptors

Cancer needs blood. In fact, some cancer medications work solely to slow or prevent cancer cells from creating new capillaries, choking off their much-needed blood and nutrient supply to halt the growth of tumors.

12 Aug 2011

New model for amyotrophic lateral sclerosis

By isolating cells from patients' spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis.

12 Aug 2011

Scientists identify new therapeutic target for ADHD, other neuropsychiatric disorders

A biochemical pathway long associated with diarrhea and intestinal function may provide a new therapeutic target for treating ADHD other neuropsychiatric disorders, according to a team of scientists from China and the United States reporting Aug. 11 in Science.

12 Aug 2011

Hi-tech tattoo that acts as heart, brain and muscle monitor

Researchers have designed a wireless electronic monitoring device so thin it can be applied to the skin like a temporary tattoo. It could one day be used to monitor heart, brain and muscle activity of patients without their even noticing.

12 Aug 2011

SIGMAR1 gene mutation associated with development of juvenile ALS

Researchers from the Kingdom of Saudi Arabia have identified a mutation on the SIGMAR1 gene associated with the development of juvenile amyotrophic lateral sclerosis.

12 Aug 2011

LifeCodexx, Sequenom partner to commercialize prenatal lab testing services in Europe

Sequenom, Inc., a life sciences company providing innovative genetic analysis solutions, today announced it has partnered with LifeCodexx AG, a company focused on the development of clinically validated Next Generation Molecular Diagnostics, for the commercialization of prenatal laboratory testing services in Europe.

11 Aug 2011

Researchers identify unknown link between migration of WBCs to infected tissues, immune memory

Researchers from Dr. Woodland's lab at the Trudeau Institute have now identified a previously unknown link between the migration of white blood cells to infected tissues and the ability of these cells to survive and become long-lived memory cells after the infection has been cleared.

11 Aug 2011

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division.

11 Aug 2011

Research: p38α MAPK protein plays a role in addiction, depression-like behavior

Researchers studying mice are getting closer to understanding how stress affects mood and motivation for drugs.

11 Aug 2011

Insight into how neural circuit forms motor plan

The voluntary movements we make must be "prepared" in our brain before they are executed. However, be it perfect timing, a false-start, or a delayed reaction, the neural circuitry underlying movement preparation is not well understood.

11 Aug 2011

New research uncovers role of p38alpha in mood disorders, addiction

Stressful experiences increase addictive drug consumption and can precipitate bouts of anxiety or depression in vulnerable people. Although the mechanisms linking stress and human behaviors are not well understood, animal models of some aspects of these behaviors have been developed and have been used to define some of the molecular events that may be responsible for stress vulnerability in people.

11 Aug 2011

Medical Science News

MYCN amplification can serve as a favorable prognostic indicator for neuroblastoma

New measurement technologies provide scientists more complete look at neurological activity

NSAIDs like ibuprofen slow the spread of breast cancers

La Jolla Institute's new RNAi Center to focus on genetics behind myriad diseases

Female sex hormone oestrogen could fight against cardiovascular disease

Medical College of Wisconsin to establish National Center for Systems Biology

Researchers discover key reason why pyrazinamide shortens duration of TB therapy

NPL scientists mimick the ways viruses infect human cells and deliver genetic material

Study links low vitamin D with early menstruation in young girls

Single engineered protein blocks two related angiogenic receptors

New model for amyotrophic lateral sclerosis

Scientists identify new therapeutic target for ADHD, other neuropsychiatric disorders

Hi-tech tattoo that acts as heart, brain and muscle monitor

SIGMAR1 gene mutation associated with development of juvenile ALS

LifeCodexx, Sequenom partner to commercialize prenatal lab testing services in Europe

Researchers identify unknown link between migration of WBCs to infected tissues, immune memory

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

Research: p38α MAPK protein plays a role in addiction, depression-like behavior

Insight into how neural circuit forms motor plan

New research uncovers role of p38alpha in mood disorders, addiction

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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