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Migraine, epilepsy and genetics: an interview with Dr. Melodie Winawer

This work is the product of an extraordinary consortium called the Epilepsy Phenome/Genome project (EPGP). It is a consortium of 27 centres in the U.S. and internationally with several hundred physicians and staff who have worked together to enrol more than 4000 patients with epilepsy and their family members.

7 Feb 2013

New method can determine seriousness of cancer prognosis with 80% certainty

The number of incorrect cancer prognoses can be halved with computerised image analysis. In three years time, the method can be used on patients with bowel cancer, ovarian cancer and prostate cancer.

6 Feb 2013

More than £6M funding awarded to enhance development of biopharmaceuticals

More than £6M of funding has been awarded to enhance the development of biopharmaceuticals. In total £6.5M will fund 12 projects to deliver commercially important results, such as industrial-scale production of antibodies, stem cell preservation at room temperature, biopharmaceutical production using microbes and commercial scale stem cell therapy.

6 Feb 2013

Boston College biologist to explore connection between peripheral neuropathy and HIV

Boston College biologist Tricia Burdo has been awarded a five-year, $1.9 million grant from the National Institutes of Health to study the role of the body's immune response in a debilitating form of nerve damage suffered by people living with HIV.

6 Feb 2013

DHA more effective than EPA in preventing liver inflammation and fibrosis

Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis - common problems that are steadily rising along with the number of Americans who are overweight.

6 Feb 2013

RRM1 gene may better predict survival for pancreatic adenocarcinoma

Moffitt Cancer Center researchers have identified a gene that may better predict survival for pancreatic adenocarcinoma, the fourth leading cause of cancer deaths in the United States.

6 Feb 2013

Researchers assess complete landscape of kinome expression in cancer

When it comes to gene sequencing and personalized medicine for cancer, spotting an aberrant kinase is a home run. The proteins are relatively easy to target with drugs and plenty of kinase inhibitors already exist.

6 Feb 2013

Paternal obesity may alter genetic mechanisms in next generations

A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine.

6 Feb 2013

Non-O blood type - the most important risk factor for venous thromboembolism

The non-O ABO blood type is the most important risk factor for venous thromboembolism (blood clots in veins), making up 20% of attributable risk for the condition, according to a new study in CMAJ (Canadian Medical Association Journal).

6 Feb 2013

GSTM gene mutation, air pollution can increase risk of asthma-related cockroach allergy

An allergic reaction to cockroaches is a major contributor to asthma in urban children, but new research suggests that the insects are just one part of a more complex story. Very early exposure to certain components of air pollution can increase the risk of developing a cockroach allergy by age 7 and children with a common mutation in a gene called GSTM may be especially vulnerable.

6 Feb 2013

Study findings suggest physical and pharmacological solutions for human stroke victims

Johns Hopkins researchers have found that mice can recover from physically debilitating strokes that damage the primary motor cortex, the region of the brain that controls most movement in the body, if the rodents are quickly subjected to physical conditioning that rapidly "rewires" a different part of the brain to take over lost function.

6 Feb 2013

Non-coding RNA MALAT1 influences lung cancer metastasis

The vast majority - approximately 80 percent - of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied group of small RNAs, there is also a class of so-called long non-coding RNAs consisting of more than 200 nucleotides.

6 Feb 2013

Oleuropein aglycone reduces inflammation associated with intestinal ischemia and reperfusion

Here's another reason why you should include olive oil in your diet: A new research report published in the Journal of Leukocyte Biology suggests that at least one compound in olive oil significantly reduces intestinal ischemia (restricted blood supply) and the resulting reperfusion injury (tissue damage caused when blood supply returns).

6 Feb 2013

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

A previously poorly investigated signalling pathway is crucial for the growth and proliferation of prostate cancer cells. An international research team discovered this when studying the enzyme "soluble adenylyl cyclase" that produces the second messenger molecule cAMP.

5 Feb 2013

Researchers pinpoint how vitamin D3 and omega-3 may boost immunity to help fight Alzheimer's

A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease.

5 Feb 2013

Regular exercise reduces development of painful diabetic neuropathy in animals

Regular exercise reduces the development of painful diabetic neuropathy in animals—apparently related to increased expression of a protective substance called "heat shock protein" 72 (Hsp72), reports an experimental study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

5 Feb 2013

MammaPrint breast cancer test can help women avoid chemotherapy

The MammaPrint breast cancer test can dramatically reduce the number of women who need to undergo chemotherapy to treat the disease, according to a newly published study.

5 Feb 2013

DCC receptor plays key role in regulating brain plasticity

Our ability to learn and form new memories is fully dependent on the brain's ability to be plastic - that is to change and adapt according to new experiences and environments. A new study from the Montreal Neurological Institute - The Neuro, McGill University, reveals that DCC, the receptor for a crucial protein in the nervous system known as netrin, plays a key role in regulating the plasticity of nerve cell connections in the brain.

5 Feb 2013

Orphan, St George's sign licensing agreement to develop new therapies for metabolic disorders

St George's, University of London has signed an exclusive worldwide licensing agreement with rare-disease research-and-development firm Orphan Technologies Ltd to develop new therapies for deadly metabolic disorders.

5 Feb 2013

UPCI researchers uncover new technique to stop growth of cancer cells

University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.

5 Feb 2013

Medical Science News

Migraine, epilepsy and genetics: an interview with Dr. Melodie Winawer

New method can determine seriousness of cancer prognosis with 80% certainty

More than £6M funding awarded to enhance development of biopharmaceuticals

Boston College biologist to explore connection between peripheral neuropathy and HIV

DHA more effective than EPA in preventing liver inflammation and fibrosis

RRM1 gene may better predict survival for pancreatic adenocarcinoma

Researchers assess complete landscape of kinome expression in cancer

Paternal obesity may alter genetic mechanisms in next generations

Non-O blood type - the most important risk factor for venous thromboembolism

GSTM gene mutation, air pollution can increase risk of asthma-related cockroach allergy

Study findings suggest physical and pharmacological solutions for human stroke victims

Non-coding RNA MALAT1 influences lung cancer metastasis

Oleuropein aglycone reduces inflammation associated with intestinal ischemia and reperfusion

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

Researchers pinpoint how vitamin D3 and omega-3 may boost immunity to help fight Alzheimer's

Regular exercise reduces development of painful diabetic neuropathy in animals

MammaPrint breast cancer test can help women avoid chemotherapy

DCC receptor plays key role in regulating brain plasticity

Orphan, St George's sign licensing agreement to develop new therapies for metabolic disorders

UPCI researchers uncover new technique to stop growth of cancer cells

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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