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New molecular imaging agent improves diagnosis of recurrent prostate cancer

Findings of a clinical trial reported at SNM's 57th Annual Meeting indicate that a new molecular imaging agent could improve diagnosis of recurrent prostate cancer and determine the best possible course of treatment for patients.

7 Jun 2010

Hunger-signaling hormone ghrelin regulates circulation of cholesterol in brain

Circulation of cholesterol is regulated in the brain by the hunger-signaling hormone ghrelin, researchers say. The finding points to a new potential target for the pharmacologic control of cholesterol levels.

7 Jun 2010

Scientists make water-free liquid from blood protein

Scientists at the University of Bristol have discovered a way to make a highly concentrated water-free liquid of a key blood protein, myoglobin, opening up the possibility of new types of biomedical materials.

6 Jun 2010

Research focuses on art, pharmaceutical drugs and the environment

Providing solutions to any current problem is the mission of analytical chemistry, according to Ms Rosa Alonso, director of the Farmartem Research Group at the University of the Basque Country. The group's name says it all with respect to the wide range of these problems - Farmartem: the abbreviation in Spanish of pharmaceuticals, art and the environment (f-rmacos, arte, medio ambiente).

5 Jun 2010

Methane-eating bacteria survive in Lost Hammer spring similar to possible springs on Mars

Researchers at McGill's department of natural resources, the National Research Council of Canada, the University of Toronto and the SETI Institute have discovered that methane-eating bacteria survive in a highly unique spring located on Axel Heiberg Island in Canada's extreme North. Dr. Lyle Whyte, McGill University microbiologist explains that the Lost Hammer spring supports microbial life, that the spring is similar to possible past or present springs on Mars, and that therefore they too could support life.

5 Jun 2010

DOE program to develop new imager for improving reliability of cancer therapy using heavy-ion beams

In 2008 the Nuclear Science Division (NSD) of the U.S. Department of Energy's Lawrence Berkeley National Laboratory launched the Applied Nuclear Physics program, headed by NSD's Kai Vetter upon his return to Berkeley after six years with Lawrence Livermore National Laboratory. One of the goals of Applied Nuclear Physics is to take experimental principles and equipment created for basic research and develop them into tools that can address practical needs like cancer therapy and homeland security.

5 Jun 2010

June Cold Spring Harbor Protocols features electrophoresis in RNA analysis and avian embryos

Gel electrophoresis is one of the most important and frequently used techniques in RNA analysis. Electrophoresis is used for RNA detection, quantification, purification by size and quality assessment. Gels are involved in a wide variety of methods including northern blotting, primer extension, footprinting and analyzing processing reactions. The two most common types of gels are polyacrylamide and agarose.

5 Jun 2010

New book highlights specific aspects of salivary gland development

Salivary glands are of utmost importance for several physiological functions ranging from the protection of teeth and surrounding soft tissues to the lubrication of the oral cavity, which is crucial for speech and perception of food taste.

5 Jun 2010

$2M federal grant to double computing power at Southwest Foundation For Biomedical Research

The "computer ranch" at the Southwest Foundation for Biomedical Research (SFBR), one of the world's largest clusters of computers for human gene research, will more than double in size this summer, thanks to a $2 million federal grant that will speed the pace of discovery at the Foundation's AT&T Genomics Computing Center.

5 Jun 2010

Researchers one step closer to understand how activity outside of nucleus determines cell's behavior

With the rapid and continuous advances in biotechnology, scientists are better able to see inside the nucleus of a cell to unlock the secrets of its genetic material. However, what happens outside of the nucleus has, in many ways, remained a mystery. Now, researchers with the National Institutes of Health are closer to understanding how activity outside of the nucleus determines a cell's behavior.

5 Jun 2010

COMMD1 protein restrains metastatic potential of invasive cancer cell line: Researchers

Researchers at UT Southwestern Medical Center have determined that cancer cells lacking a key protein are more invasive and more likely to metastasize, providing a possible drug target to combat certain tumor types.

5 Jun 2010

Estradiol plays role in development of eating disorders during puberty: MSU researchers

For the first time, scientists have discovered a possible biological culprit in the development of eating disorders during puberty: a type of estrogen called estradiol.

5 Jun 2010

High IL-10 levels in tumor cells may decrease effectiveness of autologous melanoma vaccine: Study

Scientists from the Kimmel Cancer Center at Jefferson have found that interleukin-10 production in tumor cells is a possible prognostic factor in patients with advanced melanoma who are treated with autologous melanoma cell vaccine. They are presenting their data at the 2010 ASCO Annual Meeting in Chicago (Abstract #8588).

5 Jun 2010

WRNp controls key step in pluripotent stem cell differentiation: Study

A gene shown to play a role in the aging process appears to play a role in the regulation of the differentiation of embryonic stem cells, according to researchers from the Center for Stem Cell Biology and Regenerative Medicine and the Department of Medicine at Thomas Jefferson University.

5 Jun 2010

PEB's European licensee SDX completes clinical trial for prognostic gene signature for colorectal cancer

Pacific Edge (PEB), a New Zealand-based biomedical company, today announced the successful completion of the European clinical trial for their prognostic gene signature for colorectal cancer. The clinical trial results showed a successful outcome that enables patients diagnosed with UICC stage II or UICC stage III colorectal cancer and with a high risk of disease progression to be identified and treated more appropriately.

5 Jun 2010

Biomet Biologics initiates enrollment in MarrowStim P.A.D. Kit IDE trial for critical limb ischemia

Biomet, a global leader in the manufacture of orthopedic and biotechnology products, announced today that its subsidiary, Biomet Biologics, has enrolled the first subject into its multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial for critical limb ischemia (CLI).

5 Jun 2010

Cardinal Health and UW collaborate to advance use of molecular imaging in clinical investigations and trials

Cardinal Health and the University of Washington (UW) today announced an innovative public-private collaboration designed to advance the use of molecular imaging in clinical investigations and trials.

4 Jun 2010

Ascenta Therapeutics, sanofi-aventis sign global licensing agreement for cancer drug candidates

Ascenta Therapeutics announced today the signing of a global collaboration and licensing agreement with sanofi-aventis covering several early-stage agents being investigated for their potential to restore tumor cell apoptosis (programmed cell death). These orally-active, small-molecule drug candidates inhibit the interaction between HDM2 (Human Double Minute 2) and p53, removing a block to normal p53 tumor suppressor function and potentially enhancing cancer control and treatment.

4 Jun 2010

Infinity announces Phase 2 clinical trial results of IPI-504 for NSCLC

Infinity Pharmaceuticals, Inc. today reported the results from its Phase 2 clinical trial of IPI-504, the company's i.v.-administered Hsp90 chaperone inhibitor, in patients with advanced non-small cell lung cancer (NSCLC). Data reported show that IPI-504 demonstrated clinical activity in patients with NSCLC, in particular among patients with oncogenic anaplastic lymphoma kinase (ALK) gene rearrangements.

4 Jun 2010

Earliest blood flow begins all at once

By capturing movies of both the blood and vasculature of zebrafish embryos, each less than two millimeters long, researchers have been able for the first time to see the very moment that blood begins to flow.

4 Jun 2010

Medical Science News

New molecular imaging agent improves diagnosis of recurrent prostate cancer

Hunger-signaling hormone ghrelin regulates circulation of cholesterol in brain

Scientists make water-free liquid from blood protein

Research focuses on art, pharmaceutical drugs and the environment

Methane-eating bacteria survive in Lost Hammer spring similar to possible springs on Mars

DOE program to develop new imager for improving reliability of cancer therapy using heavy-ion beams

June Cold Spring Harbor Protocols features electrophoresis in RNA analysis and avian embryos

New book highlights specific aspects of salivary gland development

$2M federal grant to double computing power at Southwest Foundation For Biomedical Research

Researchers one step closer to understand how activity outside of nucleus determines cell's behavior

COMMD1 protein restrains metastatic potential of invasive cancer cell line: Researchers

Estradiol plays role in development of eating disorders during puberty: MSU researchers

High IL-10 levels in tumor cells may decrease effectiveness of autologous melanoma vaccine: Study

WRNp controls key step in pluripotent stem cell differentiation: Study

PEB's European licensee SDX completes clinical trial for prognostic gene signature for colorectal cancer

Biomet Biologics initiates enrollment in MarrowStim P.A.D. Kit IDE trial for critical limb ischemia

Cardinal Health and UW collaborate to advance use of molecular imaging in clinical investigations and trials

Ascenta Therapeutics, sanofi-aventis sign global licensing agreement for cancer drug candidates

Infinity announces Phase 2 clinical trial results of IPI-504 for NSCLC

Earliest blood flow begins all at once

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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