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Study identifies DNA methylation entropy as a biomarker for aging

A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 12, 2025, titled "DNA methylation entropy is a biomarker for aging."

16 Apr 2025

New hope for sclerosteosis patients through Wnt pathway inhibition

Sclerosteosis arises from mutations in the SOST gene, causing abnormally high bone mass and skeletal overgrowth, which can lead to severe health issues such as hearing loss and increased intracranial pressure.

16 Apr 2025

Listening to favorite music activates the brain’s opioid system

A new imaging study by the Turku PET Centre in Finland showed that listening to favorite music affects the function of the brain's opioid system.

16 Apr 2025

Comparing single cell RNA methods to improve gastrointestinal cancer research

Research on gastrointestinal diseases, especially cancer, has mainly looked at the epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the cells that go awry to cause these diseases.

16 Apr 2025

Breakthrough method creates functional liver organoids

While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that proliferate and fully function, says Sato. When prioritizing growth and survival in laboratory settings, hepatocytes, the liver's main cells, eventually transformed into cells resembling cholangiocytes, which line the bile duct.

16 Apr 2025

Breakthrough method allows stem cell treatment for critically ill patients on ECMO

A multidisciplinary clinical team led by Professor Bernat Soria from the Institute of Bioengineering at the Miguel Hernández University of Elche (UMH, Spain) has developed a new method to deliver cell therapies in patients on extracorporeal membrane oxygenation (ECMO), a life support system used in cases of severe lung failure.

16 Apr 2025

Mitochondria found to fuel dangerous growth in aging blood stem cells

As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations.

16 Apr 2025

Study links cold hypersensitivity and heaviness in legs to varicose veins

Hypersensitivity to the cold, especially ice cold feet, as well as a feeling of heaviness in the legs, are linked to the presence of varicose veins, finds a large study published in the open access journal Open Heart.

16 Apr 2025

Study sheds light on brain regions involved in logical thinking

A team of researchers at UCL and UCLH have identified the key brain regions that are essential for logical thinking and problem solving.

16 Apr 2025

Empa scientists create innovative hydrogel for simulating the human skin

Growing cells in the laboratory is an art that humans have mastered decades ago. Recreating entire three-dimensional tissues is much more challenging.

16 Apr 2025

Study identifies brain area linked to social behavior and altruism

Are there areas of the brain, which regulate prosocial, altruistic behaviour? Together with colleagues from the universities in Lausanne, Utrecht and Cape Town, researchers from Heinrich Heine University Düsseldorf (HHU) have studied a very special group of patients and established that the "basolateral amygdala" (part of the limbic system) plays an important role in this.

16 Apr 2025

What sauerkraut can do for your gut

Fermented cabbage metabolites play a crucial role in maintaining gut barrier function, suggesting potential health benefits for inflammatory disorders.

16 Apr 2025

Promising findings for the treatment of patients with pulmonary arterial hypertension with a high risk of mortality

Pulmonary arterial hypertension (PAH) is a rare and severe lung disease with a life-threatening prognosis. After several positive trials, a recent study has confirmed the efficacy of a biotherapy, sotatercept.

16 Apr 2025

Study: Climate trauma can have lasting effects on cognitive function

A new study from University of California San Diego suggests that climate trauma - such as experiencing a devastating wildfire - can have lasting effects on cognitive function.

16 Apr 2025

Gut bacteria turn bile acids into allies against cancer

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators.

16 Apr 2025

Nasal protein levels may predict COVID-19 risk

Higher nasal expression of ACE2 and TMPRSS2 proteins can predict future SARS-CoV-2 infection.

16 Apr 2025

Modified Japanese diet shows promise for lowering blood pressure, study finds

A study of 12,213 Japanese workers found no link between hypertension and the traditional Japanese diet, but a modified version emphasizing whole grains, fruits, and dairy showed a potential protective effect. The findings highlight how modernizing traditional diets with nutrient-rich foods may combat high blood pressure.

16 Apr 2025

Low vitamin D levels damage erectile health via superoxide surge, study finds

Vitamin D deficiency directly causes erectile dysfunction by increasing superoxide and reducing protective SLPI levels, as shown in human tissue and animal models. This breakthrough reveals why low vitamin D may lead to poor sexual health and resistance to standard ED treatments.

15 Apr 2025

New study examines how obesity alters brain's reward circuits

Obesity is on the rise. Among U.S. adults aged 20 or older, 4 in 10 met the criteria for obesity in the most recent National Health and Nutrition Examination Survey, up from roughly 3 in 10 two decades earlier.

15 Apr 2025

Mid afternoon inhaler use may improve nighttime asthma control

A single daily preventer dose of inhaled corticosteroid (beclomethasone), taken mid afternoon, may be the best timing for effective asthma control as it suppresses the usual nocturnal worsening of symptoms more effectively than dosing regimens at other times of the day, suggest the results of a small clinical trial published in the journal Thorax.

15 Apr 2025