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High-resolution imaging reveals how polymyxins trigger rapid shedding of bacterial armor

A team led by UCL (University College London) and Imperial College London researchers has shown for the first time how life-saving antibiotics called polymyxins pierce the armor of harmful bacteria.

30 Sep 2025

Study quantifies pain levels with financial compensation for clinical precision

Asking people how much money they would accept to experience pain again can provide a more accurate and comparable measure of pain levels than the familiar 1-10 scale, according to an international research team led by Lancaster University.

30 Sep 2025

Researchers design factor IX variants for short- and long-term Hemophilia B management

After blood vessel damage, effective blood clotting is essential to halt bleeding. However, this process is inefficient in some individuals due to hereditary factors. Hemophilia B, for example, results from a deficiency in coagulation factor IX (FIX), which can lead to prolonged bleeding after injuries or surgery.

30 Sep 2025

What’s more dangerous, road cycling or mountain biking?

Researchers in Barcelona analyzed 149 injured cyclists and found that while mountain biking accidents were more frequent, road cycling caused more severe injuries, especially head trauma. Older age strongly increased injury severity in road cyclists, highlighting a vulnerable group in need of attention.

29 Sep 2025

Scientists test whether chaya leaves can lower blood sugar in diabetes

Researchers reviewed current evidence on the chaya plant (Cnidoscolus chayamansa), highlighting its nutritional profile, hypoglycemic activity in animal models, and potential as a complementary aid for diabetes management. While promising, safety, dosage, and interaction studies remain essential before clinical use.

29 Sep 2025

Yale researchers develop new test for early leptospirosis detection

In a new study, Yale School of Medicine (YSM) researchers unveiled a novel diagnostic method for detecting leptospiral virulence-modifying (VM) proteins in the blood and urine of hamsters, an advance that could pave the way for early diagnosis of the tropical disease leptospirosis in humans and improved treatment options.

29 Sep 2025

New TOR inhibitor rapalink-1 prolongs chronological lifespan in fission yeast

Researchers from Queen Mary University of London's School of Biological and Behavioural Sciences, using the simple fission yeast as a model, have shown that new TOR inhibitor rapalink-1 prolongs chronological lifespan.

29 Sep 2025

Breakthrough discovery reveals HIV’s survival strategy in human cells

For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating-and possibly even curing-the disease a seemingly insurmountable obstacle to achieve.

29 Sep 2025

Small molecule AVJ16 shows promise in targeting lung cancer growth

Researchers have discovered a promising new approach to lung cancer treatment. A small molecule called AVJ16 selectively blocks the cancer-driving protein IGF2BP1, halting tumor growth in preclinical studies and killing cancer cells in patient-derived models—while leaving healthy cells unharmed.

29 Sep 2025

How maternal microbes shape babies’ gut health and disease risk

Early microbial exposures from maternal microbes, milk components, and the environment shape infant gut development and long-term disease risk. The review highlights mechanisms, preventive levers, and research gaps in supporting healthy microbiome inheritance across generations.

29 Sep 2025

Cannabidiol shows promise for obesity and metabolic syndrome

Cannabidiol (CBD) shows promise in regulating appetite, glucose and lipid metabolism, and inflammation in preclinical models of obesity and metabolic syndrome. However, human evidence is still limited, highlighting the need for rigorous trials before clinical use.

29 Sep 2025

New ACC Scientific Statement highlights inflammation in cardiovascular disease

The American College of Cardiology (ACC) released today its second Scientific Statement, Inflammation and Cardiovascular Disease (CVD).

29 Sep 2025

Cornell launches new initiative to uncover how menopause shapes health and disease

Two centuries ago, few women lived long enough to reach menopause. Today, it marks a major inflection point in women's health, yet remains poorly understood. Cornell researchers aim to change that.

29 Sep 2025

Simple, affordable HPV test delivers results in less than an hour

A team of researchers led by Rice University, in collaboration with colleagues in Mozambique and The University of Texas MD Anderson Cancer Center, has developed a simple, affordable human papillomavirus (HPV) test that delivers results in less than an hour with no specialized laboratory required.

29 Sep 2025