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Mucins show promise in preventing Salmonella infections

Mucus is more than just a sticky substance: It contains a wealth of powerful molecules called mucins that help to tame microbes and prevent infection.

25 Sep 2025

Patient-derived organoids advance cancer therapy and vaccines

Tiny, three-dimensional organoid models are reshaping cancer research by recreating the intricate architecture and diversity of human tumors.

25 Sep 2025

Scientists explore how dopamine shapes myelin in social isolation

Scientists know that social isolation can alter brain structure and lead to the breakdown of myelin, the fatty coating that insulates nerve fibers in the brain. But they don't yet know exactly how or why it happens.

25 Sep 2025

Calcium-induced release identified as key driver of dangerous muscle disorders

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

25 Sep 2025

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Why do some people remain healthy through childhood yet become more vulnerable to brain disorders such as dementia later in life? A KAIST (President Kwang Hyung Lee) -led team has uncovered a key part of the answer: a developmental 'switch' in astrocytes—the brain's most abundant support cells that shapes how strongly the brain's immune system reacts in adulthood.

25 Sep 2025

Circadian clock found to regulate bone breakdown

How our bodies break down and remove old and damaged bone tissue is linked to our inner circadian clock, according to a new study from the University of Surrey and the University of Sheffield.

25 Sep 2025

Antidepressant fluoxetine alters brain energy use and boosts neural plasticity

A new study shows that the widely used antidepressant fluoxetine does more than boost serotonin levels: it changes how brain cells manage their energy and rebuild their connections, potentially helping the brain "loosen up" and adapt during depression treatment.

25 Sep 2025

Mapping 100 years of bacterial evolution reveals key spreaders of antibiotic resistance

The genetic culprits responsible for the spread of multidrug resistance (MDR) in bacteria have been identified by new research mapping 100 years of bacterial evolution.

25 Sep 2025

Lysosomal activity in worms linked to transgenerational extension of lifespan

In the Wang Lab, it's not unusual for worms to live for a long time. HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend the worm's life by up to 60 percent.

25 Sep 2025

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Scientists conducted a multiomics study of the world’s oldest verified person (117 years), uncovering protective genetic, immune, metabolic, microbiome, and epigenetic traits that supported her exceptional longevity. These findings highlight how aging and disease may, under rare circumstances, be decoupled.

25 Sep 2025

Alcohol raises dementia risk at every level of drinking, genetic study shows

Researchers using two major cohorts and Mendelian randomization found that alcohol consumption, whether light or heavy, raises the risk of dementia. Genetic evidence shows no safe level of drinking, challenging the belief that moderate intake protects brain health.

25 Sep 2025

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

This pilot study found that urinary metabolites of organophosphate pesticides were linked to reduced sperm motility in healthy young men, though results were preliminary. Oxidative stress did not explain the association, suggesting other biological pathways may be involved.

25 Sep 2025

Healthy habits linked to younger brain age

Your chronological age may say 65, but your brain could be acting a decade younger - or older - depending on your life experiences.

25 Sep 2025

Groundbreaking MRI technique reveals microvascular pulsations in the aging brain

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have developed a groundbreaking brain imaging technique that reveals how tiny blood vessels in the brain pulse with each heartbeat-changes that may hold clues to aging and diseases such as Alzheimer's.

25 Sep 2025

Discovery of EP2 receptor opens path to pain relief without blocking inflammation

Scientists at the NYU Pain Research Center have identified which receptor in prostaglandins-the hormone-like substance targeted by common painkillers-causes pain but not inflammation.

25 Sep 2025

Study uncovers how lymphatic endothelial cells assist in generating robust immune memory

A study published today in Nature Communications describes how lymphatic endothelial cells assist in generating robust immune memory, offering new insights into how the immune system functions.

25 Sep 2025

UPR modulators show promise in treating cancer-related bone disease

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation.

25 Sep 2025

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular carcinoma.

25 Sep 2025

AstroCapsules offer a new way to reduce brain inflammation

Neuroinflammation is linked to a host of detrimental brain disorders, including Alzheimer's and Parkinson's disease.

25 Sep 2025

New study suggests a connection between soft drinks and depression via the microbiome

A new study involving the German Center for Diabetes Research (DZD) provides strong evidence that sugary drinks affect not only metabolic but also mental health – especially in women. This effect is probably mediated by the sensitive microbiome of the intestine.

25 Sep 2025

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Medical Science News

Mucins show promise in preventing Salmonella infections

Patient-derived organoids advance cancer therapy and vaccines

Scientists explore how dopamine shapes myelin in social isolation

Calcium-induced release identified as key driver of dangerous muscle disorders

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Circadian clock found to regulate bone breakdown

Antidepressant fluoxetine alters brain energy use and boosts neural plasticity

Mapping 100 years of bacterial evolution reveals key spreaders of antibiotic resistance

Lysosomal activity in worms linked to transgenerational extension of lifespan

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Alcohol raises dementia risk at every level of drinking, genetic study shows

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

Healthy habits linked to younger brain age

Groundbreaking MRI technique reveals microvascular pulsations in the aging brain

Discovery of EP2 receptor opens path to pain relief without blocking inflammation

Study uncovers how lymphatic endothelial cells assist in generating robust immune memory

UPR modulators show promise in treating cancer-related bone disease

Targeting TGF-β signaling as a strategy to treat liver fibrosis

AstroCapsules offer a new way to reduce brain inflammation

New study suggests a connection between soft drinks and depression via the microbiome

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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