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New approach could improve immune checkpoint inhibitor response in MTAP-deficient tumors

Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer.

28 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

28 Sep 2023

Scientists bridge gap in understanding how the brain recognizes familiar objects

Because figuring out what is new and what is familiar in what we see is such a critically important ability for prioritizing our attention, neuroscientists have spent decades trying to figure out how our brains are typically so good at it.

28 Sep 2023

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

A groundbreaking development in biomedical engineering has led to the creation of a human stomach micro-physiological system (hsMPS), representing a significant leap forward in understanding and treating various gastrointestinal diseases, including stomach cancer.

28 Sep 2023

Advancement of potential gene therapy could offer new hope for children with Batten disease

A new study shows that delivery of gene therapy to correct the gene mutations that cause CLN2 disease, or Batten disease, directly into the cerebrospinal fluid (CSF) has potential therapeutic effects.

28 Sep 2023

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

Study uncovers previously unknown compensatory mechanism in liver disease

A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease.

28 Sep 2023

Virtual reality vs. opioids: clinical trial of non-pharmacological pain management during burn wound care

Researchers assessed the feasibility and efficacy of virtual reality as a non-pharmaceutical intervention for managing procedural pain in adult burn patients during dressing changes compared to standard opioid-based approaches.

28 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

US health care workers are at greater risk of suicide than non–health care workers

The risks of death by suicide for six healthcare worker (HCW).

28 Sep 2023

From playgrounds to peace of mind: early childhood activity's influence on middle childhood mental health

In a recent article, researchers assessed whether physical inactivity in early childhood affects mental health in middle-aged children.

28 Sep 2023

How does taking a pause on the oral contraceptive pill impact mental health?

Users of combination oral contraceptive agents experience one time per month (pill break) was connected with mood changes.

28 Sep 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

New multi-polygenic scores boost coronary heart disease prediction accuracy

Two multi-polygenic scores (muti-PGs) to predict coronary heart disease (CHD).

28 Sep 2023

Hotter days in New York linked to spike in substance abuse hospital visits

New study finds a positive correlation between rising temperatures and increased hospital visits for alcohol and substance-related disorders in New York State. The research suggests that climate change could exacerbate negative outcomes related to substance abuse.

27 Sep 2023

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

New study in Nature Medicine links yeast cells in the gastrointestinal tract to abnormal immune responses causing inflammation in Crohn's disease patients. The research suggests that these yeast-reactive T-cells could be a potential therapeutic target, offering new avenues for treatment.

27 Sep 2023

Ramadan fasting reshapes gut microbiome

Scientists investigate the effects of Ramadan intermittent fasting on gut microbiota, revealing significant alterations at both the phylum and genus levels. The study suggests that dietary intake during fasting could play a key role in these microbiota changes.

27 Sep 2023

Researchers develop new way to boost immune cells' ability to fight TB

Tuberculosis is old - ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn't been cured yet.

27 Sep 2023

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Spanish researchers use cisgenic engineering to create nutrient-packed tomatoes with higher levels of flavonoids and branched-chain amino acids, providing potential benefits for those on plant-based diets. The study shows promise for enhancing nutritional content in other crops, addressing malnutrition and health deficiencies.

27 Sep 2023

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

Harvard Medical School researcher Johan Paulsson will lead a multi-institutional $104 million effort to study bacteria and antibiotic resistance, the U.S. Department of Health and Human Services announced today.

27 Sep 2023

Medical Science News

New approach could improve immune checkpoint inhibitor response in MTAP-deficient tumors

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

Scientists bridge gap in understanding how the brain recognizes familiar objects

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

Advancement of potential gene therapy could offer new hope for children with Batten disease

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Study uncovers previously unknown compensatory mechanism in liver disease

Virtual reality vs. opioids: clinical trial of non-pharmacological pain management during burn wound care

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

US health care workers are at greater risk of suicide than non–health care workers

From playgrounds to peace of mind: early childhood activity's influence on middle childhood mental health

How does taking a pause on the oral contraceptive pill impact mental health?

Examining the cardiac pathology in fatal cases of yellow fever

New multi-polygenic scores boost coronary heart disease prediction accuracy

Hotter days in New York linked to spike in substance abuse hospital visits

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

Ramadan fasting reshapes gut microbiome

Researchers develop new way to boost immune cells' ability to fight TB

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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