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Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

What is the influence of prenatal second-hand smoke exposure on infant self-regulation?

A new study aimed to analyze an important gap concerning the impact of prenatal SHS exposure on infant self-regulation.

14 Mar 2023

Uncovering COVID-19's impact on mental health

In a recent study published in the journal BMJ, a team of researchers from Canada and the United Kingdom conducted a systematic review of current research and meta-analysis to compare the symptoms of anxiety and depression and overall mental health among the general population before and after the onset of the coronavirus disease 2019 (COVID-19) pandemic.

14 Mar 2023

Is green leaf biomass a viable and sustainable source of protein?

In a recent study published in the journal Nutrients, researchers at North Carolina State University reviewed studies on underutilized sources of plant proteins and discussed strategies to enhance yields, extract nutrients and influence the demand and acceptance of new protein sources, especially green leaf biomass.

14 Mar 2023

The burden of Clostridioides difficile infections in the United States

Researchers review existing data on Clostridioides difficile infections among United States residents.

13 Mar 2023

Kinetics of successive SARS-CoV-2 infections

Researchers compare viral kinetics of successive SARS-CoV-2 infections.

13 Mar 2023

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy.

13 Mar 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Summarizing the evidence of respiratory transmission of mpox

A recent study published in The Lancet Microbe summarized the evidence for respiratory transmission of mpox (formerly monkeypox).

13 Mar 2023

What are the risk factors associated with post-acute SARS-CoV-2 infection?

In a recent study posted to the Research Square* preprint server, researchers assessed the risk factors and predictive models for post-acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

13 Mar 2023

How does SARS-CoV-2 interact with other pathogens?

In a recent study published in the PLOS Pathogens journal, researchers examine the present body of information regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interactions.

13 Mar 2023

No increased risk of neuropsychiatric events in children born to mothers using leukotriene-receptor antagonists in pregnancy

A new study examined the associations between leukotriene-receptor antagonists (LTRAs) use in pregnancy and neuropsychiatric events (NEs) risk in the offspring.

13 Mar 2023