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How is the host’s m6A mRNA profile affected during SARS-CoV-2 infection?

Researchers observed that SARS-CoV-2 infection results in loss of N6-methyladenosine modification in cellular RNAs.

15 Dec 2022

What is the role of the pediatric gut microbiome in COVID-19?

Recently, scientists have reviewed the available evidence on the gut microbiome in children with COVID-19 and published it in Microorganisms.

15 Dec 2022

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Researchers estimated influenza VE in patients aged ≥6 months seeking outpatient care for ARI due to the influenza A(H3N2) virus between October 2021 and April 2022 in the United States (US).

15 Dec 2022

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

HKUMed researchers at AIDS Institute, Department of Microbiology and Department of Surgery, School of Clinical Medicine, and School of Biomedical Sciences discover the role of an isoformic programmed cell death protein 1 (PD-1), namely Δ42PD-1, in suppressing the function of killer T cells, which is a type of immune cells essential for killing cancer cells among hepatocellular carcinoma (HCC) patients.

15 Dec 2022

Study assesses COVID-19 booster vaccination coverage by demographics and behaviors and experiences toward vaccination among fully vaccinated adults

An early release from the CDC, USA, examines the coverage of booster doses among adults in the USA.

15 Dec 2022

Study finds altered spontaneous brain activity in people with Down syndrome

Researchers of the Faculty of Psychology, the Institute of Neurosciences and the Institute of Complex Systems of the University of Barcelona have identified, using functional magnetic resonance techniques, differences in the spontaneous activity of the brain in a resting state in people with Down syndrome (DS) compared to the general population. Also, these variations could be related to cognitive skills.

15 Dec 2022

Four genetic mutations linked to progressive multifocal leukoencephalopathy

New research has confirmed a strong link between four genetic mutations and progressive multifocal leukoencephalopathy (PML), a rare but often fatal brain infection that can be triggered by dozens of FDA-approved drugs.

14 Dec 2022

Vaping may negatively affect pulmonary surfactant in the lungs, study shows

A recently published preclinical study by researchers at Lawson Health Research Institute and Western University's Schulich School of Medicine & Dentistry, show that vaping may negatively affect pulmonary surfactant in the lungs.

14 Dec 2022

Research reveals that a viral toxin may contribute to the severity of COVID-19

Researchers determine whether the SARS-CoV-2 spike protein influences endothelial and epithelial barrier dysfunction and vascular leakage.

14 Dec 2022

Severity of COVID-19 in men may be due to the loss of Y chromosome

Men are at an increased risk of a severe bout of COVID-19 compared to women. Researchers at Uppsala University have now shown that this may be due to loss of the Y chromosome in part of their white blood cells.

14 Dec 2022

Study finds a novel therapeutic target for prevention and treatment of gout

Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin and Thomas Jefferson.

14 Dec 2022

Flexible assemblies of nerve cells appear to be key to successful episodic memory

For the first time, scientists have recorded human nerve cells firing together in flexible assemblies, a process that appears necessary to successfully encode long-term memories, a study led by UT Southwestern researchers reports.

14 Dec 2022

Updated guidelines seek to improve transparency and utility in clinical trial reporting

In a global study of outcome reporting in clinical trials, a research team at The Hospital for Sick Children (SickKids) has issued updated guidelines on what should be included in all trial protocols and published clinical trial reports, with the goal to improve their transparency and utility.

14 Dec 2022

Weak electrical pulses can stop certain life-threatening arrhythmias, study shows

Atrial and ventricular fibrillations are dangerous heart arrhythmias that claim millions of lives each year. Current treatment for them is a high-energy defibrillation shock that can be intensely painful and lead to further heart damage.

14 Dec 2022

Subcutaneous fat protects against brain inflammation in females

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

14 Dec 2022

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

Scientists have developed a set of siRNAs against SARS-CoV-2 using computational approaches.

14 Dec 2022

The therapeutic effects and safety of psychedelics

Psychedelics are reported to have rapid-onset and long-lasting therapeutic benefits after a single or few doses.

14 Dec 2022

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Researchers elucidated the mechanisms of long-term T lymphocyte lodgement in tissues other than lymphoid tissues and the reasons for the transient residency of specific subsets of tissue-resident memory T (TRM) lymphocytes.

14 Dec 2022

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Researchers evaluated the change in symptoms and risk factors associated with positive SARS-CoV-2 tests during the COVID-19 pandemic and compared it to those associated with positive tests of other respiratory viruses among residents of King County, Washington, in the United States.

14 Dec 2022

What is the relation between COVID-19 vaccination and new POTS-related diagnoses?

Researchers assessed the association between POTS and SARS-CoV-2 infections and COVID-19 vaccinations.

14 Dec 2022

Medical Science News

How is the host’s m6A mRNA profile affected during SARS-CoV-2 infection?

What is the role of the pediatric gut microbiome in COVID-19?

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

Study assesses COVID-19 booster vaccination coverage by demographics and behaviors and experiences toward vaccination among fully vaccinated adults

Study finds altered spontaneous brain activity in people with Down syndrome

Four genetic mutations linked to progressive multifocal leukoencephalopathy

Vaping may negatively affect pulmonary surfactant in the lungs, study shows

Research reveals that a viral toxin may contribute to the severity of COVID-19

Severity of COVID-19 in men may be due to the loss of Y chromosome

Study finds a novel therapeutic target for prevention and treatment of gout

Flexible assemblies of nerve cells appear to be key to successful episodic memory

Updated guidelines seek to improve transparency and utility in clinical trial reporting

Weak electrical pulses can stop certain life-threatening arrhythmias, study shows

Subcutaneous fat protects against brain inflammation in females

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

The therapeutic effects and safety of psychedelics

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

What is the relation between COVID-19 vaccination and new POTS-related diagnoses?

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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