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Mouse study unravels mechanisms by which the brain consolidates remote fear memories

A remote fear memory is a memory of traumatic events that occurred in the distant past - a few months to decades ago.

23 Dec 2022

Sleep duration declines during mid-life than in early and late adulthood

People sleep less in mid-adulthood than they do in early and late adulthood, finds a new study led by UCL, University of East Anglia and University of Lyon researchers.

23 Dec 2022

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.

23 Dec 2022

Targeting Piezo2 could provide new avenue for treating chronic pain related to gastrointestinal disorders

Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome.

23 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents.

23 Dec 2022

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Researchers described a messenger ribonucleic acid (mRNA)-lipid nanoparticle monkeypox vaccine encoding four conserved monkeypox virus surface proteins which induced monkeypox virus-specific immunity and elicited heterologous protection when challenged with lethal vaccinia virus.

23 Dec 2022

Study shows de novo origination of functional microproteins

In a new study, researchers performed a genomic analysis to investigate the origination of human microproteins of biological importance.

23 Dec 2022

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Researchers evaluated plasma samples from individuals vaccinated with a fourth booster dose of mono- or bivalent mRNA SARS-CoV-2 vaccine to evaluate the recognition and neutralization capacity against the ancestral (D614G) strain and the Omicron BQ.1.1 subvariant.

23 Dec 2022

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

A new study evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in Argentinian children when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron were predominant.

23 Dec 2022

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

A new paper presents preliminary evidence that a new vaccine candidate, designed to boost immunity in already immunized individuals, and containing the adjuvanted Beta spike variant protein antigen, can induce a potent cross-neutralizing antibody response in non-human primate models that is detectable for up to three months.

23 Dec 2022

Children less likely to transmit infectious particles, study finds

Infectious diseases are often transmitted via particles exhaled from infected persons. Yet, the size of such aerosol particles varies greatly, depending on its origin in the respiratory tract.

22 Dec 2022

Wearable skin patch could help clinicians diagnose tumors, organ malfunction and more

Novel skin patch capable of deep detection of hemoglobin and core temperature.

22 Dec 2022

Mice study sheds light on how the brain's primary motor cortex helps suppress neuropathic pain

A new study in mice has helped illuminate how the brain's primary motor cortex (M1) – a brain region most commonly associated with control of motor functions – helps suppress dimensions of neuropathic pain.

22 Dec 2022

Research sheds light on how mRNA boosters affect the durability of antibodies to COVID-19

New research from the University of Virginia School of Medicine speaks to the benefits of a COVID-19 booster.

22 Dec 2022

Cystic fibrosis drug shows promise to treat pneumonia

Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome.

22 Dec 2022

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia.

22 Dec 2022

Partial knee arthroplasty yields faster functional recovery than total knee replacement

For selected patients with knee osteoarthritis, unicompartmental (or "partial") knee arthroplasty (UKA) shortens the recovery time for two key measures of physical function, as compared with total knee arthroplasty (TKA), reports a randomized trial in The Journal of Bone & Joint Surgery.

22 Dec 2022

Extracellular vesicles enhance cancer immunotherapy

Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumors sensitive to a type of immunotherapy drug called a checkpoint inhibitor.

22 Dec 2022

Physicians reveal main risk factors for sudden death from a colloid cyst

RUDN University physicians investigated known cases of sudden death from a colloid cyst. After analyzing the data, the authors named the main risk factors and told what to look for. The results are published in the Journal of Clinical Neuroscience.

22 Dec 2022

Medical Science News

Mouse study unravels mechanisms by which the brain consolidates remote fear memories

Sleep duration declines during mid-life than in early and late adulthood

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

Targeting Piezo2 could provide new avenue for treating chronic pain related to gastrointestinal disorders

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Study shows de novo origination of functional microproteins

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

Children less likely to transmit infectious particles, study finds

Wearable skin patch could help clinicians diagnose tumors, organ malfunction and more

Mice study sheds light on how the brain's primary motor cortex helps suppress neuropathic pain

Research sheds light on how mRNA boosters affect the durability of antibodies to COVID-19

Cystic fibrosis drug shows promise to treat pneumonia

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

Partial knee arthroplasty yields faster functional recovery than total knee replacement

Extracellular vesicles enhance cancer immunotherapy

Physicians reveal main risk factors for sudden death from a colloid cyst

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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