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Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Researchers presented the results of a phase III randomized controlled trial of oral SARS-CoV-2 antiviral VV116.

3 Jan 2023

Study suggests a single dose of JYNNEOS vaccine may lessen the severity of mpox illness

Researchers pursued evidence that the JYNNEOS vaccine offered some protection against the mpox disease, especially they confirmed the duration for which the one dose of this vaccine conferred protection.

3 Jan 2023

How can we characterize the burden of post-acute sequelae of COVID-19 in the community?

Researchers characterized the burden of post-acute sequelae of coronavirus disease 2019 (COVID-19) [PASC] in community-dwelling individuals.

3 Jan 2023

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

Researchers longitudinally evaluated humoral immune responses to the second and third doses of COVID-19 mRNA vaccines among individuals with and without prior history of SARS-CoV-2 infections.

3 Jan 2023

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

Researchers evaluated whether insulin-like peptide 3 (INSL3) could predict hypogonadism and age-associated morbidity in older males.

3 Jan 2023

What is the impact of COVID-19 on the human genetic architecture?

Researchers recently described the second update on the study of human genetic architecture with respect to the effect of coronavirus disease 2019 (COVID-19).

3 Jan 2023

Deep learning tool identifies mosaic mutations that cause disease

Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are extremely difficult to detect because they exist in a tiny percentage of the cells.

2 Jan 2023

Underlying genetic cause for MIS-C complications after COVID-19 identified

A recent Science journal study determined the underlying cause of MIS-C related to SARS-CoV-2 in some children. It hypothesized that monogenic inborn errors of immunity (IEI) is the primary reason for this condition. Identifying these inborn errors is expected to help elucidate the disease's cellular, molecular, and immunological basis.

2 Jan 2023

Mouse study identifies potential targets for treating dry eye disease and corneal injury

People with a condition known as dry eye disease are more likely than those with healthy eyes to suffer injuries to their corneas.

2 Jan 2023

Good hydration may slow down aging and prolong disease-free life

Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine.

2 Jan 2023

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Dr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University Hospital Bonn (UKB), was awarded the C. E. Alken Prize in recognition of his outstanding scientific uro-oncological work.

30 Dec 2022

Predictive models using serum miRNAs may offer objective criteria for referral to early palliative care services

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients."

29 Dec 2022

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

What are the long-term consequences following COVID-19 and other viral respiratory infections?

Researchers compared coronavirus disease 2019 (COVID-19)-specific long-term consequences to other viral respiratory infections.

29 Dec 2022

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

Medical Science News

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Study suggests a single dose of JYNNEOS vaccine may lessen the severity of mpox illness

How can we characterize the burden of post-acute sequelae of COVID-19 in the community?

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

What is the impact of COVID-19 on the human genetic architecture?

Deep learning tool identifies mosaic mutations that cause disease

Underlying genetic cause for MIS-C complications after COVID-19 identified

Mouse study identifies potential targets for treating dry eye disease and corneal injury

Good hydration may slow down aging and prolong disease-free life

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Predictive models using serum miRNAs may offer objective criteria for referral to early palliative care services

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

What are the long-term consequences following COVID-19 and other viral respiratory infections?

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Could the adoption of a Mediterranean diet improve pregnancy outcomes?

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Misperceptions of verticality happen when body pitch and translational self-motion come together

AI won't replace radiologists, yet!

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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