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Study reveals cellular basis of antigen-specific response to Pfizer-BioNTech’s COVID-19 vaccine

Researchers in the United States have provided important insights into the antigen-specific cellular response and evolving humoral (antibody) response to messenger RNA- (mRNA) based vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

29 Jul 2021

Is it possible to identify pre-symptomatic and asymptomatic COVID-19 clinically?

The COVID-19 pandemic has severely impacted morbidity and mortality in nursing home residents across the world. Earlier detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may help better mitigate the risk of viral transmission. As both pre-symptomatic and asymptomatic transmission is common in these outbreaks, screening for threshold temperatures of 38°C or higher could miss timely detection in most infected people.

29 Jul 2021

99% of COVID-19 deaths in Italy occur among those not fully vaccinated

In a new report out of Italy, health officials reported that almost 99 percent of people who have died from COVID-19 since February 2021 were not fully vaccinated. The report released by the National Health Institute (ISS) showed that the few fully vaccinated people who died of COVID-19 were also older than those who died without complete COVID-19 vaccine doses.

29 Jul 2021

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

A new study focuses on the impact of vaccines on the changes in the symptoms in the PASC group.

27 Jul 2021

Genomic test may help identify prostate cancer patients at high risk of disease progression

After a biopsy comes back positive for prostate cancer, patients and their doctors are often left with a choice between taking a watch-and-wait approach, known as active surveillance, or proceeding with surgery or radiation.

27 Jul 2021

How SARS-CoV-2 vaccination symptoms differ from early COVID-19 symptoms

A new study published on the preprint server medRxiv* presents an analysis of the differences between recorded vaccination side effects vs. early COVID-19 symptoms. The researchers focused on four vaccines, namely, Pfizer-BioNTech (PB) mRNA (BNT162b2) vaccine, based on messenger ribonucleic acid encoding the viral spike protein; the Moderna mRNA (mRNA-1273) vaccine; the Oxford-AstraZeneca (O-AZ) adenovirus-vectored vaccine; and the Janssen adenovirus-vectored Ad26.COV2.S).

26 Jul 2021

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

A recent study conducted as a part of the Real-Time Assessment of Community Transmission-2 (REACT-2) program has estimated the seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies among adult populations in England.

25 Jul 2021

First dose of Pfizer-BioNTech or Oxford-AstraZeneca vaccines has strong protective effect against COVID-19 in older adults

A new study estimates vaccine effectiveness against COVID-19 mortality in England using the RDD approach.

22 Jul 2021

U.S. sees sharp decrease in life expectancy largely due to COVID-19 pandemic, CDC says

New preliminary data from the United States Centers for Disease Control and Prevention (CDC) suggests that average life expectancy in the United States fell by 1.5 years over 2020.

21 Jul 2021

Thai study looks at CoronaVac vaccine vs. natural immunity to SARS-COV-2 variants

A new study evaluates the efficacy of vaccine- and infection-induced antibodies against SARS-CoV-2 variants.

19 Jul 2021

How do immunocompromised patients respond to COVID-19 vaccines?

The COVID-19 vaccines produce a boost in antibody activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, new research suggests vaccine responses aren’t all created equal. Their findings showed that immunocompromised patients, such as transplant recipients, with no prior exposure to SARS-CoV-2 produce little to no neutralizing antibodies.

18 Jul 2021

Infection fatality rate of COVID-19 in community-based elderly lower than earlier estimates

A new study discusses the results obtained from various seroprevalence studies conducted in 2020.

18 Jul 2021

“Herd immunity” not responsible for Sweden’s control of COVID-19, say researchers

Researchers in Sweden have challenged the interpretation that variable non-pharmaceutical interventions (NPIs) and “herd immunity” protection are responsible for the rise and fall of coronavirus disease 2019 (COVID-19) epidemic waves in hard-hit locations where authorities have not enforced strict NPIs.

14 Jul 2021

Research identifies key role of CXCL9 cytokine in age-related chronic inflammation

An inflammatory-aging clock called developed by Stanford University School of Medicine and the Buck Institute for Research on Aging can predict how strong your immune system will be in 10 years, when you'll become frail or whether you may develop cardiovascular diseases a few years down the road.

14 Jul 2021

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

Researchers in the United States have provided a high-resolution description of the viral dynamics involved in acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

14 Jul 2021

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

Breathing treatments are provided to hospitalized COVID-19 patients. In this study, the researchers examined the community composition in relation to three attributes - COVID-19 status, breathing assistance, and antibiotic use. This study is published in the journal, Applied Microbiology.

12 Jul 2021

Socioeconomic inequities and structural racism are neglected pieces of SARS-CoV-2 transmission networks

A recent perspective article published in the prestigious journal Science highlights how the use of network-driven strategies for adequately informing rapidly emergent epidemic responses is not only evidence-based but also an equitable way forward for the current coronavirus disease (COVID-19) pandemic and future respiratory pandemics.

12 Jul 2021

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

Researchers in Israel have conducted a study showing that the use of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine appears to be safe and effective among patients with cancer.

11 Jul 2021

MRI screening and targeted biopsies could reduce overdiagnoses of prostate cancer

Most countries have not introduced nationwide prostate-cancer screening, as current methods result in overdiagnoses and excessive and unnecessary biopsies. A new study by researchers at Karolinska Institutet in Sweden, which is published in The New England Journal of Medicine, indicates that screening by magnetic resonance imaging (MRI) and targeted biopsies could potentially cut overdiagnoses by half.

9 Jul 2021

Women at higher risk of post-COVID-19 syndrome

To better understand post-COVID sequelae, researchers at the University Hospital Basel and the University Hospital Zurich conducted a multicentre prospective observational cohort study.

8 Jul 2021

Men's Health News

Study reveals cellular basis of antigen-specific response to Pfizer-BioNTech’s COVID-19 vaccine

Is it possible to identify pre-symptomatic and asymptomatic COVID-19 clinically?

99% of COVID-19 deaths in Italy occur among those not fully vaccinated

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

Genomic test may help identify prostate cancer patients at high risk of disease progression

How SARS-CoV-2 vaccination symptoms differ from early COVID-19 symptoms

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

First dose of Pfizer-BioNTech or Oxford-AstraZeneca vaccines has strong protective effect against COVID-19 in older adults

U.S. sees sharp decrease in life expectancy largely due to COVID-19 pandemic, CDC says

Thai study looks at CoronaVac vaccine vs. natural immunity to SARS-COV-2 variants

How do immunocompromised patients respond to COVID-19 vaccines?

Infection fatality rate of COVID-19 in community-based elderly lower than earlier estimates

“Herd immunity” not responsible for Sweden’s control of COVID-19, say researchers

Research identifies key role of CXCL9 cytokine in age-related chronic inflammation

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

Socioeconomic inequities and structural racism are neglected pieces of SARS-CoV-2 transmission networks

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

MRI screening and targeted biopsies could reduce overdiagnoses of prostate cancer

Women at higher risk of post-COVID-19 syndrome

Increasing your risk of IBD through processed food

World Brain Day 2021: An interview with Professor Alan Thompson

Preventing lethal blood clots

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