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How video gaming may shape sleep, diet, and activity across the lifespan

This narrative review found that video gaming can have both benefits and risks for health across the lifespan. It may provide short-term stress relief and social connection, but frequent or prolonged gaming is also associated with sedentary behaviour, poorer sleep, disrupted eating patterns, and lower diet quality, with effects shaped by age, sex, timing, content, and motivation.

31 Mar 2026

How gut imbalance may drive obesity, diabetes, and heart disease

A new review argues that gut dysbiosis is closely linked to metabolic dysfunction through intertwined effects on inflammation, oxidative stress, gut barrier integrity, microbial metabolites, and epigenetic regulation. It also highlights microbiome-targeted strategies such as high-fiber diets, probiotics, prebiotics, postbiotics, exercise, and fecal microbiota transplantation as promising ways to support metabolic health.

30 Mar 2026

PSMA therapy may postpone hormone treatment in prostate cancer patients

Where previous research showed that PSMA therapy for prostate cancer can prolong the lives of patients who have exhausted all other treatment options, a new study now demonstrates that the therapy is also effective in an earlier stage of the disease.

30 Mar 2026

Study links atrial fibrillation to poorer brain clearance and cognitive decline

Researchers found that people with atrial fibrillation had lower MRI-based glymphatic activity and poorer cognitive performance than healthy controls, with the greatest impairment seen in non-paroxysmal AF. In patients who underwent catheter ablation, glymphatic activity improved after sinus rhythm was restored, suggesting a possible link between heart rhythm, brain waste clearance, and cognition.

30 Mar 2026

Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growth

Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable AP-1-linked chromatin changes and later amplifies tumour outgrowth after oncogenic mutation.

29 Mar 2026

APOE4 alters brain immunity and cognition differently in females and males

APOE4 drove sex-specific changes in meningeal immunity, lymphatic drainage, brain lipids, neuroinflammation, and cognition in mouse models, with females showing greater inflammatory and cognitive vulnerability. Suppressing innate immunity improved some cognitive outcomes in female E4/E4 mice but worsened them in male E4/E4 mice, underscoring the need for sex-tailored approaches.

29 Mar 2026

Heavily processed foods may raise heart disease risk beyond poor nutrition alone

A 2026 review in Cardiology in Review reports that higher intake of ultra-processed foods is consistently associated with greater risks of cardiovascular disease, stroke, and cardiovascular mortality across cohort studies and meta-analyses. The paper also highlights plausible mechanisms involving gut dysbiosis, oxidative stress, and NF-κB-driven inflammation, with additives such as emulsifiers, preservatives, dyes, and sweeteners discussed as potential contributors.

26 Mar 2026

50 years of data reveal higher death risks in London transport workers

A 50-year retrospective cohort study of 117,166 Transport for London workers found that bus and London Underground job categories had higher all-cause, respiratory, cardiovascular, and lung cancer mortality than office workers. The authors caution that broad job categories, missing cause-of-death data, and unmeasured confounding mean the findings show association, not proof of specific occupational causes.

26 Mar 2026

Men show major gaps in male fertility knowledge, study finds

A study of 156 adult men found that knowledge about male fertility was generally low across both medical and lifestyle-related topics, with only 5 of 25 questions answered correctly by most respondents. Older men, those with a medical background, and those with suspected or treated infertility tended to score higher, while supplement use was common despite limited fertility literacy.

26 Mar 2026

UPFs before conception may shape fertility and embryo growth

Findings show ultraprocessed food consumption before conception influences fertility and embryonic development, urging further research in this area.

26 Mar 2026

New fathers face delayed mental health risks after childbirth

Paternal mental health risks increase after childbirth, with delayed detection of psychiatric disorders underscoring the need for targeted support for fathers.

26 Mar 2026

Estradiol patches as effective as injections for locally advanced prostate cancer

Hormone patches are as good at controlling locally advanced prostate cancer as the injections typically used to deliver hormone therapy, according to the results of a large clinical trial led by UCL (University College London) researchers.

25 Mar 2026

Detailed cell atlas reveals earliest changes in prostate cancer

Prostate cancer affects one in five Australian men, making it the most common cancer in the country.

25 Mar 2026

Moderate coffee intake may lower heart failure risk

A systematic review and dose-response meta-analysis of seven prospective cohorts found that drinking 2 to 4 cups of coffee a day was associated with a modestly lower risk of incident heart failure. The lowest estimated risk appeared at 1 to 2 cups daily, although the evidence for a true non-linear J-shaped pattern was suggestive rather than definitive.

24 Mar 2026

Wholegrain rye changes gut bacteria and lowers inflammation in obesity trial

In a 12-week randomized trial, replacing refined wheat with wholegrain rye in a calorie-restricted diet did not produce greater weight loss in adults with overweight or obesity. Wholegrain rye did, however, lower C-reactive protein and alter gut microbiota and short-chain fatty acids in ways that may have positive cardiometabolic implications.

24 Mar 2026

CREB5 drives stem cell-like transcriptional programs in aggressive prostate cancer

A new research paper was published in Volume 17 of Oncotarget on March 17, 2026, titled "CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer."

24 Mar 2026

Leaving home may worsen diet quality in young adults, Australian study finds

Australian longitudinal data suggest that leaving the parental home is associated with a small decline in overall diet quality and a short-term rise in discretionary food intake during the transition from adolescence to adulthood. The study also found that diet quality tended to worsen most among those moving in with a partner, while the discretionary-food gap narrowed over time.

23 Mar 2026

New NYU study identifies lower heat risk thresholds for vulnerable older adults

Nationally, heat-related mortality has risen by nearly 17 % per year since 2016. As a result, New York City now issues heat alerts and opens cooling centers when the heat index is forecast to reach 95 degrees Fahrenheit or higher for at least two consecutive days or a heat index of 100 degrees Fahrenheit or higher for any length of time.

23 Mar 2026

Higher meat intake may slow cognitive decline in older adults with APOE ε4

In older Swedish adults, higher meat intake was associated with slower cognitive decline and lower dementia risk among people carrying APOE ε3/ε4 or ε4/ε4, but not among other genotype groups. A higher processed-to-total meat ratio was linked to worse dementia outcomes, while unprocessed red meat and poultry showed no substantial difference.

22 Mar 2026

GLP-1 drugs cut heart and kidney risks in type 1 diabetes study

In a large target trial emulation of 174,678 people with type 1 diabetes, GLP-1 receptor agonist initiation was associated with lower risks of major cardiovascular events and end-stage kidney disease over five years. The study also found no increased risk of hospitalization for diabetic ketoacidosis or severe hypoglycemia, supporting further randomized trials of GLP-1RAs as adjunctive therapy in type 1 diabetes.

22 Mar 2026