Molecular & Structural Biology

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Study reveals how people with retinal degenerative disease can maintain night vision

New insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time has been published today in the open-access eLife journal.

22 Sep 2020

New national research and training hub at UW-Madison could transform medicine

A national research initiative announced today will place the University of Wisconsin-Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography - technologies that can illuminate life at the atomic scale.

22 Sep 2020

Consumption of cooked carrots can also trigger allergic reactions, finds study

The consumption of raw carrots triggers allergic reactions in many people. Contrary to popular belief, cooked carrots can also have this effect.

21 Sep 2020

Experimental set-up allows researchers to examine brain processes in birds during active tasks

How do birds make decisions and which brain regions are particularly active when they solve tasks? Researchers from the Department of Biopsychology at Ruhr-Universität Bochum (RUB) are investigating these questions.

19 Sep 2020

Scientists identify new area of the brain involved in cost-benefit decision-making

Every day, we make hundreds of decisions. While most are small and inconsequential, like choosing what to eat or wear, others are more complex and involve weighing up potential costs and benefits, like deciding whether to study more for a better grade instead of hanging out with friends.

19 Sep 2020

Cannabinoids cause changes in the brain that leads to deficiencies in social interaction

The nervous system comprises neurons and glial cells (glia signifies "glue"). Astrocytes are the most abundant among the glial cells.

19 Sep 2020

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and late 1800s, respectively, immunotherapy has more recently emerged as a viable and successful approach to cancer treatment.

18 Sep 2020

New methods help to accurately identify cancers’ hidden genetic losses, duplications

Understanding the specific mutations that contribute to different forms of cancer is critical to improving diagnosis and treatment.

17 Sep 2020

PARP enzymes can bring two broken DNA ends together, shows study

Scientists at St. Jude Children's Research Hospital have identified the structure of double-strand DNA break repair by PARP enzymes. The findings show that PARP2 can bridge the gap, bringing two broken DNA ends together.

16 Sep 2020

Study implicates new gene as driver of motor neuron diseases

Failures in a quality control system that protects protein-building fidelity in cells can lead to motor neuron degeneration and related diseases, according to a new study from an international team co-directed by Scripps Research molecular biologist Claudio Joazeiro, PhD.

16 Sep 2020

Researchers develop 3D functional heart organoids from mouse embryonic stem cells

Heart development as it happens in vivo, or in a living organism, is a complex process that has traditionally been difficult to mimic in vitro, or in the laboratory.

16 Sep 2020

Bacterial movement is powered by tiny protein motor

The ability to move is key for bacteria like some strains of salmonella and E. coli to efficiently spread infections. They can propel themselves forward using threads, known as flagella, powered by the flagellar rotary motor.

15 Sep 2020

Genetic risk factor for late-onset Alzheimer's disease has early effects on the brain

A genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with certain memory tasks.

15 Sep 2020

Scientists unravel the molecular mechanism underlying the causes of colorectal cancer

A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.

15 Sep 2020

Buckling could trigger embryo morphogenesis

The embryo of an animal first looks like a hollow sphere. Invaginations then appear at different stages of development, which will give rise to the body's structures (the brain, digestive tract, etc.).

14 Sep 2020

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Myotonic dystrophy type I is the most common type of adult-onset muscular dystrophy. People with the condition inherit repeated DNA segments that lead to the toxic buildup of repetitive RNA, the messenger that carries a gene's recipe to the cell's protein-making machinery.

14 Sep 2020

Immune system study helps illuminate a surprising mind-body connection

New research at Washington University School of Medicine in St. Louis helps illuminate a surprising mind-body connection.

14 Sep 2020

TRESK regulates the brain's circadian clock to differentiate behavior between day and night

Research from the University of Kent has found that TRESK, a calcium regulated two-pore potassium channel, regulates the brain's central circadian clock to differentiate behavior between day and night.

14 Sep 2020

DNA damage may occur far away from the point of incidence of radiation

Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers of Karlsruhe Institute of Technology have demonstrated that DNA damage may also occur far away from the point of incidence of the radiation.

14 Sep 2020

Exploring sex differences in gene expression

Males and females share the vast majority of their genomes. Only a sprinkling of genes, located on the so-called X and Y sex chromosomes, differ between the sexes. Nevertheless, the activities of our genes--their expression in cells and tissues--generate profound distinctions between males and females.

12 Sep 2020

Molecular & Structural Biology

Study reveals how people with retinal degenerative disease can maintain night vision

New national research and training hub at UW-Madison could transform medicine

Consumption of cooked carrots can also trigger allergic reactions, finds study

Experimental set-up allows researchers to examine brain processes in birds during active tasks

Scientists identify new area of the brain involved in cost-benefit decision-making

Cannabinoids cause changes in the brain that leads to deficiencies in social interaction

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

New methods help to accurately identify cancers’ hidden genetic losses, duplications

PARP enzymes can bring two broken DNA ends together, shows study

Study implicates new gene as driver of motor neuron diseases

Researchers develop 3D functional heart organoids from mouse embryonic stem cells

Bacterial movement is powered by tiny protein motor

Genetic risk factor for late-onset Alzheimer's disease has early effects on the brain

Scientists unravel the molecular mechanism underlying the causes of colorectal cancer

Buckling could trigger embryo morphogenesis

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Immune system study helps illuminate a surprising mind-body connection

TRESK regulates the brain's circadian clock to differentiate behavior between day and night

DNA damage may occur far away from the point of incidence of radiation

Exploring sex differences in gene expression

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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