Molecular & Structural Biology

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Oxytocin blocks excess drinking in alcohol-dependent rats

The neuropeptide oxytocin blocks enhanced drinking in alcohol-dependent rats, according to a study published April 16 in the open-access journal PLOS Biology led by Drs. Tunstall, Koob and Vendruscolo of the National Institutes of Health, and Drs. Kirson and Roberto of The Scripps Research Institute.

17 Apr 2019

Timing of food intake influences molecular clock in the liver of mice

The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report April 16 in the journal Cell Reports.

17 Apr 2019

Ensuring 100% Accuracy in Antibody Protein Sequencing

The purpose of antibody protein sequencing is to accurately deduce every single amino acid present in the primary sequence. This is an issue with isoleucine and leucine which have the same molecular weight. Rapid Novor has developed a technique to determine these with 100% accuracy.

From Rapid Novor Inc 16 Apr 2019

Rockefeller scientists develop novel microscopy technique that peers deep into the brain

In order to understand the brain, scientists must be able to see the brain--cell by cell, and moment by moment.

16 Apr 2019

Researchers complete large analysis of new gene fusion responsible for development of cancers

A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion they believe is responsible for development of a wide spectrum of cancer types.

16 Apr 2019

Neuronal transport factor detects its target transcripts in more complex manner than previously thought

A team of scientists from Helmholtz Zentrum München and the University of Ulm has discovered that the neuronal transport factor Staufen2 scans and binds to its target transcripts in a much more complex manner than previously thought.

16 Apr 2019

New study sheds light on how extreme temperature hampers spermatogenesis in insects

The scientific community has long held an understanding about the effect of temperature on sperm production in mammals, but this new study sheds light on how spermatogenesis in insects is hampered at extreme temperatures.

15 Apr 2019

Scientists present a new approach to fight cancer

In recent years, it's become clear that RNA-binding proteins play a major role in cancer growth. These proteins, active in all cells but especially so in cancer cells, bind to RNA molecules and accelerate cancer cell growth.

15 Apr 2019

Leica Microsystems receives FDA De Novo clearance for blue light fluorescence module

Leica Microsystems has received DeNovo clearance from the FDA to market its FL400 surgical microscope filter in the United States for characterization of tumor tissue in neurosurgery.

From Leica Microsystems GmbH 15 Apr 2019

Spotlight on ECCMID 2019: Detecting Disease & Managing Infections

This article covers some of the highlights of ECCMID 2019, with insights into some of the companies and products being featured at the event.

From ESCMID 15 Apr 2019

Removing damaged mitochondria may relieve chronic inflammatory conditions

Researchers have discovered a potential new way to treat chronic inflammatory diseases, by eliminating damaged mitochondria before they trigger excessive inflammation.

12 Apr 2019

Large-scale screen of mouse mutants reveals 38 new genes involved in hearing loss

A large-scale screen of mouse mutants has revealed multiple new genes involved in hearing loss, according to a study publishing April 11 in the open-access journal PLOS Biology by Karen Steel of King’s College London and the Wellcome Sanger Institute, and colleagues.

12 Apr 2019

DNA fragments from ancient hominins reveal new branches of the Denisovan lineage

It's widely accepted that anatomically modern humans interbred with their close relatives, the Neanderthals and Denisovans, as they dispersed out of Africa.

12 Apr 2019

A new role for sensory signals in the brain discovered

Learning how to tie a shoe or shoot a basketball isn't easy, but the brain somehow integrates sensory signals that are critical to coordinating movements so you can get it right.

12 Apr 2019

Bacteria share genes with one another, even across tissue boundaries

Bacteria in the human body are sharing genes with one another at a higher rate than is typically seen in nature, and some of those genes appear to be traveling - independent of their microbial hosts - from one part of the body to another, researchers report in the journal Scientific Reports.

11 Apr 2019

Characterizing Small Molecules with NMR

In this interview, Marcel Lachenmann describes the importance of characterizing small molecules in the pharma, food and polymer industry and how NMR achieves this.

From Oxford Instruments NMR 11 Apr 2019

Biochemical switches could be triggered to treat pathology of IBM, ALS and FTD

St. Jude Children's Research Hospital scientists have found that the enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that kill muscle and brain cells.

11 Apr 2019

Key gene involved in transmission of African sleeping sickness identified

Life scientists from UCLA and the University of Bern have identified a key gene in the transmission of African sleeping sickness -- a severe disease transmitted by the bite of infected tsetse flies, which are common in sub-Saharan Africa.

10 Apr 2019

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

A new molecule -EPB-53-, could help fight type 2 diabetes and the non-alcoholic fatty liver disease, according to a new study led by the team of Manuel Vázquez-Carrera, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the University of Barcelona, and the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Center.

10 Apr 2019

Bruker announces innovative UHF magnet technology for high-resolution NMR in structural biology

At the 60th Experimental Nuclear Magnetic Resonance Conference (ENC, www.enc-conference.org ), Bruker announced today a breakthrough in ultra-high field high-resolution NMR spectroscopy applied to structural biology and the study of functional intrinsically disordered proteins.

From Bruker BioSpin - NMR, EPR and Imaging 10 Apr 2019

Molecular & Structural Biology

Oxytocin blocks excess drinking in alcohol-dependent rats

Timing of food intake influences molecular clock in the liver of mice

Ensuring 100% Accuracy in Antibody Protein Sequencing

Rockefeller scientists develop novel microscopy technique that peers deep into the brain

Researchers complete large analysis of new gene fusion responsible for development of cancers

Neuronal transport factor detects its target transcripts in more complex manner than previously thought

New study sheds light on how extreme temperature hampers spermatogenesis in insects

Scientists present a new approach to fight cancer

Leica Microsystems receives FDA De Novo clearance for blue light fluorescence module

Spotlight on ECCMID 2019: Detecting Disease & Managing Infections

Removing damaged mitochondria may relieve chronic inflammatory conditions

Large-scale screen of mouse mutants reveals 38 new genes involved in hearing loss

DNA fragments from ancient hominins reveal new branches of the Denisovan lineage

A new role for sensory signals in the brain discovered

Bacteria share genes with one another, even across tissue boundaries

Characterizing Small Molecules with NMR

Biochemical switches could be triggered to treat pathology of IBM, ALS and FTD

Key gene involved in transmission of African sleeping sickness identified

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

Bruker announces innovative UHF magnet technology for high-resolution NMR in structural biology

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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