Molecular & Structural Biology

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Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model.

18 Jul 2019

Researchers reveal molecular cause for severe multi-organ disorder

Three unrelated families on three continents (from continental Portugal, the United States and Brazil), all with healthy ancestors, had children with a very rare disease.

18 Jul 2019

Research team detects novel mechanism of inheritance

Non-Mendelian, oligogenic inheritance could bean unrecognized and important element for occurrence ofhereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness.

18 Jul 2019

Study defines how diarrhea-causing rotavirus initially interacts with the host

Research by the Department of Microbiology of the University of Valencia, the Institute of Biomedicine of Valencia and the Institute of Agrochemistry and Food Technology of the CSIC has defined the initial interaction of human rotavirus P [8] (the main cause of gastroenteritis) with the recipients of the intestine.

18 Jul 2019

Novel insight into microRNA function can be crucial for the development of gene therapy

Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei.

18 Jul 2019

Study: Megakaryocytes play an important role in cell migration

Hematopoiesis is the process of forming blood cells, which occurs predominantly in the bone marrow. The bone marrow produces all types of blood cells: red blood cells, platelets, and white blood cells.

18 Jul 2019

Molecular switches may control lifespan and healthspan separately, genetic discovery suggests

Aging research indicates that better healthspan--the quality of life as we age--may be more important than lifespan.

17 Jul 2019

Slug serves as 'command central' for determining breast stem cell health

A new study published in Cell Reports found that a transcription factor called Slug serves as 'command central' for determining breast stem cell health, regulating both stem cell activity and repair of DNA damage.

17 Jul 2019

New method spots rare immune cells reactive against cancer

Researchers from the Garvan Institute of Medical Research have developed a new method to spot rare immune cells that are reactive against cancer cells, from within a patient's own immune system.

16 Jul 2019

Removing bacterial armor could be new way to fight anthrax

A new study led by Dr. Antonella Fioravanti in the lab of Prof. Han Remaut (VIB-VUB Center for Structural Biology) has shown that removing the armor of the bacterium that causes anthrax slows its growth and negatively affects its ability to cause disease.

16 Jul 2019

Discovery could pave the way towards new treatments for neurological disorders

Scientists at the University of Warwick have discovered a new process that sets the fastest molecular motor on its marathon-like runs through our neurons.

16 Jul 2019

EMBL study reveals uncoupling between chromatin topology and gene expression

Molecular biologists long thought that domains in the genome’s 3D organization control how genes are expressed.

16 Jul 2019

Researchers use blood samples from zoo to improve computer-assisted disease prognosis

The researchers want to use similar genetic patterns, which have been present in the blood of humans and animals for thousands of years, to improve computer-assisted disease prognosis.

16 Jul 2019

Research reveals the parenting habits of our earliest extinct ancestors

Extended parental care is considered one of the hallmarks of human evolution. A stunning new research result published today in Nature reveals for the first time the parenting habits of one of our earliest extinct ancestors.

15 Jul 2019

Scientists discover hundreds of protein-pairs through coevolution study

Scientists have discovered hundreds of new protein-protein interactions by looking for co-evolution in some residues of aligned protein sequences.

15 Jul 2019

Study measures antioxidant levels in edible insects

For the first time, a study has measured antioxidant levels in commercially available edible insects.

15 Jul 2019

Rhythmic movement can be coordinated without neuronal interactions between body parts

Scientists at Hokkaido University and Hiroshima University have found that green brittle stars with five arms show a different "pumping" movement pattern than those with six arms.

14 Jul 2019

Researchers discover gene linked to healthy aging in worms

People with the same lifespan do not necessarily have the same quality of life. As we live longer, extending quality of life -- "healthspan" -- is gaining importance.

12 Jul 2019

Exciting study shows how centrioles center the process of cell division

All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells.

12 Jul 2019