Molecular & Structural Biology

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Research provides new insights into how telomeres regulate cellular senescence

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have further uncovered the secrets of telomeres, the caps that protect the ends of our chromosomes.

30 Jun 2017

Research presents crystal structure of enzyme implicated in cancer, neurodegenerative diseases

A Stony Brook University-led team of researchers has determined the structure of a key enzyme involved with cell growth regulation in cancer and neurodegenerative diseases, including Alzheimer's disease.

28 Jun 2017

Morgridge researchers reveal complex viral replication process in unprecedented detail

In the fight against the viruses that invade everyday life, seeing and understanding the battleground is essential. Scientists at the Morgridge Institute for Research have, for the first time, imaged molecular structures vital to how a major class of viruses replicates within infected cells.

27 Jun 2017

Researchers develop new technique to capture neuron activity

Many cognitive processes, such as decision-making, take place within seconds or minutes. Neuroscientists have longed to capture neuron activity during such tasks, but that dream has remained elusive -- until now.

27 Jun 2017

Researchers uncover three-dimensional structure of tetanus toxin protein

"Our discovery could be used to design new medicines", says Pål Stenmark, Associate Professor at the Department of Biochemistry and Biophysics, Stockholm University.

27 Jun 2017

Combined effect of genetic change and ozone exposure could increase risk for autism

A new analysis shows that individuals with high levels of genetic variation and elevated exposure to ozone in the environment are at an even higher risk for developing autism than would be expected by adding the two risk factors together.

23 Jun 2017

Two-test combination accurately identifies benign pancreatic lesions

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign.

23 Jun 2017

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

The leading cause of acute gastroenteritis linked to eating raw seafood disarms a key host defense system in a novel way: It paralyzes a cell's skeleton, or cytoskeleton.

23 Jun 2017

Could the mTOR pathway be used to protect against cancer?

The mTOR pathway is probably the main pathway in humans and other animals that drives growth. That is, the accumulation of mass and adding mass to make an organism bigger by both making more cells, and making cells grow and become bigger.

22 Jun 2017

Researchers create new camera that can register fast processes in transparent specimens

Researchers from ITMO University have built a setup for recording holograms of tiny objects like living cells with a femtosecond speed. The new method allows one to reconstruct phase topography of a studied sample according to deformations that emerge in a laser pulse when it passes through the specimen.

22 Jun 2017

Researchers examine formation of functional amyloids by bacteria in real time

A team of scientists from the VIB lab of Han Remaut and the lab of Yves Dufrêne at UCL Louvain-La-Neuve collaborated on a study of functional amyloids -protein aggregates with the typical amyloid structure that do not lead to disease but rather serve a dedicated biological function.

21 Jun 2017

Cells key to blood vessel formation can also produce tumors and enable their spread

While it's widely held that tumors can produce blood vessels to support their growth, scientists now have evidence that cells key to blood vessel formation can also produce tumors and enable their spread.

20 Jun 2017

Exposure to light at night suppresses biting, manipulates flight behavior in mosquitoes

Scientists at the University of Notre Dame have found that exposure to just 10 minutes of light at night suppresses biting and manipulates flight behavior in the Anopheles gambiae mosquito, the major vector for transmission of malaria in Africa, according to new research published in the journal Parasites and Vectors.

16 Jun 2017

Findings may contribute to better understanding of aging and cancer development

A team of researchers led by Dr. Dennis Kappei, a Special Fellow from the Cancer Science Institute of Singapore at the National University of Singapore, has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging.

14 Jun 2017

Scientists create new method to make peptide stapling widely available

UK scientists have created a new method to structure peptides, which they say will be cheaper and make the process of using stapled peptides in drug discovery much more widely available.

2 Jun 2017

WPI research program aims to understand gender differences in neurobiology

Many complicated neurological disorders appear to have a gender bias. Women, for example, are more likely to develop Alzheimer's disease, while men are at greater risk for Parkinson's disease.

17 May 2017

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

In their quest to replicate themselves, viruses have gotten awfully good at tricking human cells into pumping out viral proteins. That's why scientists have been working to use viruses as forces for good: to deliver useful genes to human cells and help patients who lack important proteins or enzymes.

12 May 2017

Molecular & Structural Biology

Research provides new insights into how telomeres regulate cellular senescence

Research presents crystal structure of enzyme implicated in cancer, neurodegenerative diseases

Morgridge researchers reveal complex viral replication process in unprecedented detail

Researchers develop new technique to capture neuron activity

Researchers uncover three-dimensional structure of tetanus toxin protein

Combined effect of genetic change and ozone exposure could increase risk for autism

Two-test combination accurately identifies benign pancreatic lesions

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

Could the mTOR pathway be used to protect against cancer?

Researchers create new camera that can register fast processes in transparent specimens

Researchers examine formation of functional amyloids by bacteria in real time

Cells key to blood vessel formation can also produce tumors and enable their spread

Exposure to light at night suppresses biting, manipulates flight behavior in mosquitoes

Findings may contribute to better understanding of aging and cancer development

Scientists create new method to make peptide stapling widely available

WPI research program aims to understand gender differences in neurobiology

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

Using the CLARITY Technique for Spinal Cord Rehabilitation and Repair

Developing a Micro-CT Scanner for Preclinical Imaging

The Importance of Flexibility in Spectrophotometry

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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