Molecular & Structural Biology

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Aging and lung tissue stiffness contribute to function decline

New research suggests that certain areas of the lungs are more likely than others to show age-related damage that compromises respiratory function. The paper is published ahead of print in the American Journal of Physiology - Lung Cellular and Molecular Physiology.

9 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Study reveals key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study in Molecular Cell from scientists at Johns Hopkins Bloomberg School of Public Health.

8 Mar 2018

Neurogenesis diminishes after childhood, finds study

In a recent study, scientists concluded that adult neurogenesis, which is seen in other species, does not occur in human beings.

8 Mar 2018

Female mosquito brain map may help uncover neural circuitry behind biting and other behaviors

A mosquito's head is about the size of a pencil tip, but it packs a dangerous punch: it is the delivery system for malaria, yellow fever, and Zika, among other blood-borne diseases. In most mosquito species, females are the more dangerous sex. They're the ones drinking - and transferring - blood.

7 Mar 2018

Salk researchers uncover power switch for muscles

If you've ever wondered how strenuous exercise translates into better endurance, researchers at the Salk Institute may have your answer. In a study published in the journal Cell Reports on March 6, 2018, scientists in Ronald Evans' lab have shown that the protein ERRγ (ERR gamma) helps deliver many of the benefits associated with endurance exercise.

6 Mar 2018

New technique provides pairs of genetically matched cells to study disease

Researchers led by Dr. Knut Woltjen report a new gene editing method that can modify a single DNA base in the human genome with absolute precision.

6 Mar 2018

Study uncovers new target in Parkinson’s disease

A new study has uncovered a relationship between the presence of Lewy bodies and neuronal cell death in Parkinson's disease.

6 Mar 2018

Study reveals relationship between circadian rhythm and mitochondrial network

Cellular energy metabolism also follows the rhythm of the circadian clock. A University of Basel study has now shown exactly how this works by revealing the relationship between the circadian rhythm and the mitochondrial network for the first time.

6 Mar 2018

Researchers use 3D jet writer to model metastatic cancer

Researchers have developed a 3D printer that uses polymers to generate a lifelike cancer microenvironment.

5 Mar 2018

Study sheds light on neuronal responses in ALS

In a recent study, scientists have linked changes in the size of motor neurons to the onset of symptoms in motor neurone disease (ALS).

5 Mar 2018

Tradeshow Talks with Harrick Scientific

We talked to Jeff from Harrick Scientific about their new products at Pittcon 2018.

From Harrick Scientific 5 Mar 2018

New study shows advantages of DNA barcoding technique for identifying nanoparticles

The first direct comparison of in vitro and in vivo screening techniques for identifying nanoparticles that may be used to transport therapeutic molecules into cells shows that testing in lab dishes isn't much help in predicting which nanoparticles will successfully enter the cells of living animals.

5 Mar 2018

Antibiotic use may affect efficacy of cancer immunotherapies

Antibiotic use is known to have a near-immediate impact on our gut microbiota and long-term use may leave us drug-resistant and vulnerable to infection.

2 Mar 2018

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Dr. Alicia G. Arroyo, have identified a function of a protease that could be targeted for the treatment of some infections and even tumor metastasis.

2 Mar 2018

McGill scientists invent new technique for measuring enzyme inhibition

Researchers at McGill University have invented a new technique for measuring how quickly drugs interact with their molecular targets. The discovery provides scientists with a new way to investigate the effectiveness of drug candidates that might otherwise have been overlooked.

2 Mar 2018