Molecular & Structural Biology

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Researchers recapitulate the human form of arrhythmogenic cardiomyopathy in zebrafish model

The research groups of Jeroen Bakkers (Hubrecht Institute/UMC Utrecht) and Toon van Veen (UMC Utrecht) bring forward the first patient-specific model for the heart disease arrhythmogenic cardiomyopathy (ACM).

9 Dec 2021

SARS-CoV-2 Omicron variant may bind with ACE2 receptor more efficiently

A new study discusses the effect of the Omicron variant’s mutations on its binding efficiency to the ACE2 receptor.

9 Dec 2021

Scientists determine structure of the molecule associated with ALS for the first time

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Study reveals how a protein in the blood is attracted to key component of Adenovirus-based vaccines

A collaborative team from the School of Medicine at the University of Cardiff, Wales and a range of US institutions used the UK's national synchrotron, Diamond Light Source, to help reveal the details of how a protein in the blood is attracted to a key component of Adenovirus based vaccines.

8 Dec 2021

Researchers identify a molecular culprit for COVID-19's seasonal nature

Not to pile on, but winter is coming and the COVID-19 pandemic is about to get worse. Not necessarily because of omicron – scientists are still working that one out – but because there’s more evidence than ever that COVID-19 is a seasonal disease.

8 Dec 2021

Researchers uncover the journey of microglia in developing zebrafish

Microglia, the immune cells of the brain, form the first line of defense against neurodegenerative diseases and traumatic brain injuries.

8 Dec 2021

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Researchers investigate the conformational dynamics of the SARS-CoV-2 RBD using the atomistic molecular dynamics simulation method.

7 Dec 2021

Study shows the existence of efficient coding processes for visual stimuli in rodents

A collaboration between SISSA and the University of Pennsylvania indicates the existence of an efficient process of sensory coding in rats, suggesting a general principle for optimal use of computational resources.

7 Dec 2021

Gene expression related to liver metabolism altered by spaceflight

The latest findings of a series of studies on mice that examined harmful effects caused by spending time in space show that gene expression related to liver metabolism is altered in response to the space environment.

6 Dec 2021

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

SARS-CoV-2 causes the pandemic coronavirus disease COVID-19, that is more harmful for elderly people, who show more severe symptoms and are at higher risk of hospitalization and death.

3 Dec 2021

Cannabis vapor exposure generationally affects sperm counts and motility in mice

An intense but short-term exposure to cannabis vapor lowered sperm counts and slowed sperm movement, or motility, not only in the directly exposed male mice but also in their sons.

2 Dec 2021

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new study by researchers at Massachusetts General Hospital.

2 Dec 2021

Researchers introduce new method for observing cell interactions

Researchers created a system that allows scientists to ‘log’ a cell’s reactions to external stimuli within the cell’s genetic material.

2 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

Neural network 'hallucinates' proteins with new, stable structures

Just as convincing images of cats can be created using artificial intelligence, new proteins can now be made using similar tools. In a report in Nature, a team including researchers at the University of Washington, Rensselaer Polytechnic Institute, and Harvard University describe the development of a neural network that "hallucinates" proteins with new, stable structures.

1 Dec 2021

Study sheds light on Aβ deposition patterns in the brain from external sources

Alzheimer's disease (AD) involves the deposition of a protein called amyloid β protein (Aβ) in the brain. This protein can build up in both the functional tissues, or "parenchyma", of the brain, and in the blood vessels.

30 Nov 2021

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

A research team at the University of Córdoba is studying the alterations that occur in the immune system's T lymphocytes with respect to age and in relation to the cytomegalovirus herpesvirus.

29 Nov 2021

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

The proteins that belong to the HAT family are essential for life as they transport amino acids across the cell membrane. Although the members of this family are practically identical, some transport certain amino acids and not others.

29 Nov 2021

Biologists discover how a protein in our body works

It's an old needlework trick, and a protein in our body knows it: Instead of threading yarn into the eye from the end, it can be easier to pass a loop through it.

29 Nov 2021

Tomosyn protein's key contribution to heterogeneity of neurons revealed

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be remembered, when their circuit partners change, or other conditions emerge.

29 Nov 2021

Molecular & Structural Biology

Researchers recapitulate the human form of arrhythmogenic cardiomyopathy in zebrafish model

SARS-CoV-2 Omicron variant may bind with ACE2 receptor more efficiently

Scientists determine structure of the molecule associated with ALS for the first time

Study reveals how a protein in the blood is attracted to key component of Adenovirus-based vaccines

Researchers identify a molecular culprit for COVID-19's seasonal nature

Researchers uncover the journey of microglia in developing zebrafish

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Study shows the existence of efficient coding processes for visual stimuli in rodents

Gene expression related to liver metabolism altered by spaceflight

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

Cannabis vapor exposure generationally affects sperm counts and motility in mice

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

Researchers introduce new method for observing cell interactions

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Neural network 'hallucinates' proteins with new, stable structures

Study sheds light on Aβ deposition patterns in the brain from external sources

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

Biologists discover how a protein in our body works

Tomosyn protein's key contribution to heterogeneity of neurons revealed

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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