Molecular & Structural Biology

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Researchers invent new technique to measure the speed of fibril growth

Amyloid fibrils are deposits of proteins in the body that join together to form microscopic fibres. Their formation has been linked to many serious human diseases including Alzheimer's, Parkinson's and Type 2 diabetes.

16 Apr 2021

UZH study establishes an objective neurobiological measure for stress resilience

Researchers at the University of Zurich show that increased sensitivity in a specific region of the brain contributes to the development of anxiety and depression in response to real-life stress.

15 Apr 2021

DNAJC9 protein plays a key role in safeguarding histones, shows study

In the cell nucleus histones play a crucial role packaging DNA into chromatin. Histones are however very sticky to both DNA and RNA, so to ensure they are transported to the cell nucleus after synthesis and bind to the right portion of DNA to organize the chromatin, they are guarded by complexes of histone chaperones.

15 Apr 2021

New research could help solve major challenge in the deployment of COVID-19 vaccines

New research by University of Texas at Dallas scientists could help solve a major challenge in the deployment of certain COVID-19 vaccines worldwide -- the need for the vaccines to be kept at below-freezing temperatures during transport and storage.

15 Apr 2021

Ebola virus's key protein uses molecular triggers in the human cell to change shape

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape - and biologists are taught that defined shape dictates the protein's destined function.

15 Apr 2021

Mouse model closely replicates human NAFLD

Human non-alcoholic fatty liver disease (NAFLD) is a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver cancer and ultimately requires liver transplant.

13 Apr 2021

Novel ultrasensitive assay to measure cathepsin B in the blood

Scientists at the Walter Reed Army Institute for Research demonstrated the potential of a novel blood test for cathepsin B, a well-studied protein important to brain development and function, as an indicator for a range of disease states.

13 Apr 2021

Researchers discover molecular signatures of aging process in mice

Researchers have identified molecular signatures of the aging process in mice, publishing their results today in the open-access eLife journal.

13 Apr 2021

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis.

13 Apr 2021

DNA supercoiling is involved in the control of gene expression

The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information.

13 Apr 2021

Early exposure to smell can affect perception and social behavior later in life

Imprinting is a popularly known phenomenon, wherein certain animals and birds become fixated on sights and smells they see immediately after being born.

13 Apr 2021

Exercise could be used to improve the oral environment in people with NAFLD

Liver disease, from metabolic and bacterial causes, is a growing concern. What connects these dots? The gut, or more specifically, bacteria in the gut.

12 Apr 2021

Research may lead to a significant breakthrough in the battle against deadly brain tumors

Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer.

12 Apr 2021

Study finds a bacterial molecule that may be key to fighting gastric cancer

Humans are exposed to many types of bacteria daily, the majority of which are harmless. However, some bacteria are pathogenic, which means they can cause disease.

12 Apr 2021

Plasticizers can impair important brain functions in humans

The plasticizers contained in many everyday objects can impair important brain functions in humans. Biologists from the University of Bayreuth warn of this danger in an article in Communications Biology.

12 Apr 2021

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Researchers at IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences - demonstrate that different viruses can lead to brain malformations through diverse mechanisms by using human brain organoid models.

9 Apr 2021

Tiny SARS-CoV-2 protein may have big implications for future COVID-19 treatments

A tiny protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future treatments, according to a team of Penn State researchers.

9 Apr 2021

Study reveals molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions by utilizing rubredoxin B, a protein from a rubredoxin family that play an important role in adaptation to changing environmental conditions.

9 Apr 2021

Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Researchers exploring the developing central nervous system of fruit flies have identified nonelectrical cells that transition the brain from highly plastic into a less moldable, mature state.

8 Apr 2021

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds.

8 Apr 2021

Molecular & Structural Biology

Researchers invent new technique to measure the speed of fibril growth

UZH study establishes an objective neurobiological measure for stress resilience

DNAJC9 protein plays a key role in safeguarding histones, shows study

New research could help solve major challenge in the deployment of COVID-19 vaccines

Ebola virus's key protein uses molecular triggers in the human cell to change shape

Mouse model closely replicates human NAFLD

Novel ultrasensitive assay to measure cathepsin B in the blood

Researchers discover molecular signatures of aging process in mice

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

DNA supercoiling is involved in the control of gene expression

Early exposure to smell can affect perception and social behavior later in life

Exercise could be used to improve the oral environment in people with NAFLD

Research may lead to a significant breakthrough in the battle against deadly brain tumors

Study finds a bacterial molecule that may be key to fighting gastric cancer

Plasticizers can impair important brain functions in humans

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Tiny SARS-CoV-2 protein may have big implications for future COVID-19 treatments

Study reveals molecular mechanisms of drug resistance in Mycobacterium tuberculosis

Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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