Molecular & Structural Biology

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Researchers study how glycans activate SARS-CoV-2

One thing that makes SARS-CoV-2, the virus that causes COVID-19, elusive to the immune system is that it is covered in sugars called glycans.

25 Feb 2021

Research shows effective strategy to target the SARS-CoV-2 spike protein

The virus that causes COVID-19 belongs to the family of coronaviruses, "corona" referring to the spikes on the viral surface. These spikes are not static - to infect cells, they change shapes.

25 Feb 2021

Study reveals molecular details of SARS-CoV-2 interactions with human cells

In order to infect cells, SARS-CoV-2, the virus that causes COVID-19, needs to insert itself into the membrane of human cells. New molecular models show what parts of SARS-CoV-2 are critical for that interaction, revealing new potential drug targets.

25 Feb 2021

Process of molecular sorting emerges from combination of two spontaneous mechanisms, indicates study

The eukaryotic cell is the basic unit of animals and plants. At the microscope, it looks highly structured and subdivided in many membrane-bound compartments.

25 Feb 2021

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited.

24 Feb 2021

Understanding Absolute Stoichiometry of Oligomeric Protein Complexes Using SEC-MALS

News-Med interviews .... about using SEC-MALS to characterize the native oligomeric state of Nap proteins and their complexes.

24 Feb 2021

New gene-editing tool enables programming of sequential cuts over time

Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time.

23 Feb 2021

Scientists discover mechanism by which epithelial tumors cause maturation defects

Conducted on the fly Drosophila, the study shows that tumors caused by chromosomal instability delay entry into the adult phase.

23 Feb 2021

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Monoclonal antibodies are part of the therapeutic arsenal for eliminating cancer cells. Some make use of the immune system to act and belong to a class of treatment called "immunotherapies." But how do these antibodies function within the tumor? And how can we hope to improve their efficacy?

22 Feb 2021

Insights into molecular tools shared across coronaviruses could provide potential target for COVID-19

Coronaviruses exploit our cells so they can make copies of themselves inside us. After they enter our cells, they use our cell machinery to make unique tools of their own that help them generate these copies.

22 Feb 2021

Study reveals mechanism for translation of maternally inherited mitochondrial genome

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

22 Feb 2021

Researchers uncover 'hotspots' on the Spike protein that are critical for SARS-CoV-2 infection

The COVID-19 pandemic has prompted considerable investigation into how the SARS-CoV-2 Spike protein attaches to a human cell during the infection process, as this knowledge is useful in designing vaccines and therapeutics.

22 Feb 2021

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows

When you slip into sleep, it's easy to imagine that your brain shuts down, but University of Michigan research suggests that groups of neurons activated during prior learning keep humming, tattooing memories into your brain.

22 Feb 2021

Novel vectors reduce the risks associated with ocular gene therapies

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development.

22 Feb 2021

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Long-term sleep deprivation is detrimental to health, increasing the risk of psychiatric and somatic disorders, such as depression and cardiovascular diseases.

22 Feb 2021

Researchers study how the methylation of proteins affects different mitochondrial processes

Disorders of the cells' energy supply can cause a number of serious diseases, but also seem to be connected to aging.

20 Feb 2021

Study provides new information about the structure of prion proteins

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

20 Feb 2021

Molecular & Structural Biology

Researchers study how glycans activate SARS-CoV-2

Research shows effective strategy to target the SARS-CoV-2 spike protein

Study reveals molecular details of SARS-CoV-2 interactions with human cells

Process of molecular sorting emerges from combination of two spontaneous mechanisms, indicates study

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

Understanding Absolute Stoichiometry of Oligomeric Protein Complexes Using SEC-MALS

New gene-editing tool enables programming of sequential cuts over time

Scientists discover mechanism by which epithelial tumors cause maturation defects

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Insights into molecular tools shared across coronaviruses could provide potential target for COVID-19

Study reveals mechanism for translation of maternally inherited mitochondrial genome

Researchers uncover 'hotspots' on the Spike protein that are critical for SARS-CoV-2 infection

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows

Novel vectors reduce the risks associated with ocular gene therapies

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Researchers study how the methylation of proteins affects different mitochondrial processes

Study provides new information about the structure of prion proteins

Study: Longevity gene protects brain stem cells from the harmful effects of stress

Researchers discover first evidence of protein folding driven by liquid-liquid phase separation

Meta-study provides an overall picture of the neural basis of sign language

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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