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New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

In a recent research paper currently available on bioRxiv* preprint server, scientists from the University of Oxford in the United Kingdom and the University of Auckland in New Zealand identified several structural specificities of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may serve as viable starting points for the development and optimization of viral inhibitors against coronavirus disease 2019 (COVID-19) and other future threats.

16 Mar 2022

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Researchers evaluate the virucidal effects of ELAH against SARS-CoV-2 and human coronavirus-229E in a nasal spray formulation.

15 Mar 2022

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers use molecular docking to screen phytocompounds and evaluate their binding affinity with SARS-CoV-2.

15 Mar 2022

Anti-spike IgG dynamics after 2nd BNT162b2 COVID-19 vaccine dose in Japanese health care workers

Researchers investigate the dynamics of anti-spike IgG levels against the SARS-CoV-2 spike protein in Japanese healthcare workers.

15 Mar 2022

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Stand Up To Cancer and Zentalis Pharmaceuticals, Inc. today announced that Zentalis will contribute $1 million to the SU2C Catalyst program to support research that investigates the use of certain small molecule inhibitors for treating a variety of cancer types.

15 Mar 2022

High doses of antibiotic may safely and effectively treat TB meningitis

A Johns Hopkins Children's Center-led study in animals suggests that high doses of a widely used antibiotic called rifampin may safely treat and reduce the duration of treatment for the deadliest form of tuberculosis that affects the brain, potentially improving survival rates for patients and decreasing the likelihood of lasting adverse effects of the disease.

15 Mar 2022

‘An Arm and a Leg’: Need an expensive drug? Here’s what you need to know

Lillian Karabaic teaches personal finance to millennials through a podcast and community called Oh My Dollar! — and she needs an expensive drug to treat a chronic condition.

15 Mar 2022

Patients taking prescription opioids are at higher risk of developing mood disorders

People who are prescribed opioids for pain relief have a higher risk of developing mood disorders such as anxiety, University of Queensland researchers have found.

14 Mar 2022

Antiseptic drug found to be as effective as antibiotics for UTI prevention in women

The antiseptic drug methenamine hippurate is as good as antibiotics for preventing recurrent urinary tract infections in women, finds a trial published by The BMJ today.

10 Mar 2022

Study examines the safety, efficacy of old 'forgotten' antibiotic for treating resistant bacterial infections

The results make it possible to expand the treatment options for infections for which few alternatives exist, while at the same time helping to avoid increasing resistance to the usual drugs.

10 Mar 2022

The trajectory of B-cell immunity six months after mRNA vaccination

Researchers assess SARS-CoV-2 antibodies in individuals vaccinated with a mRNA COVID-19 vaccine six months after receiving their second dose.

10 Mar 2022

Assessment of oligonucleotides as COVID-19 treatment

A recent study posted to the bioRxiv* pre-print server assessed the ability of oligonucleotides in preventing the development of infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions.

8 Mar 2022

Study shows anti-itch and pain relief potential of protein in tick saliva

A protein found in tick saliva could be turned into a drug that eases itching and chronic pain in people.

8 Mar 2022

French study shows COVID vaccine efficacy 94% against severe outcomes

A recent paper published on the medRxiv preprint server utilized data from three national databases containing an abundance of information on Covid-19 screening (SI-DEP), vaccination (VAC-SI), and hospitalizations (SI-VIC) in France to provide additional perspectives on vaccine effectiveness and its evolution over the year 2021 in the French context.

7 Mar 2022

Pharmaceutical News

New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Acacetin shows potency against SARS-CoV-2 spike protein

Anti-spike IgG dynamics after 2nd BNT162b2 COVID-19 vaccine dose in Japanese health care workers

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

High doses of antibiotic may safely and effectively treat TB meningitis

‘An Arm and a Leg’: Need an expensive drug? Here’s what you need to know

Patients taking prescription opioids are at higher risk of developing mood disorders

Antiseptic drug found to be as effective as antibiotics for UTI prevention in women

Study examines the safety, efficacy of old 'forgotten' antibiotic for treating resistant bacterial infections

The trajectory of B-cell immunity six months after mRNA vaccination

Assessment of oligonucleotides as COVID-19 treatment

Study shows anti-itch and pain relief potential of protein in tick saliva

French study shows COVID vaccine efficacy 94% against severe outcomes

What does the Future Look Like for Patient Centricity within Clinical Trials?

Patients divided over Alzheimer’s drug: Is it a ‘risk I’m willing to take’ or just a ‘magic pill’?

Myocarditis and pericarditis in COVID-19 vaccine recipients

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

$35 insulin cap is welcome, popular, and bipartisan. But Congress may not pass it anyway.

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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