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Folate increases risk of breast cancer in women with certain genetic make-up

In most women folate, a type of B vitamin, reduces the risk of breast cancer. However, in women with a certain genetic make-up it has shown to be the opposite: folate raises the risk of breast cancer.

7 Apr 2010

Illumina launches VeraCode ADME Core Panel

Illumina, Inc. today announced the launch of its VeraCode ADME Core Panel designed to help researchers study genetic predispositions for differential drug response and adverse events. The VeraCode ADME Core Panel offers the most complete representation of the key biomarkers associated with drug absorption, distribution, metabolism and excretion (ADME) as standardized by pharmaceutical industry experts in the PharmADME Core List.

From Illumina, Inc. 7 Apr 2010

Health Robotics introduces Virtual High-Availability Architecture for CytoCare and i.v.STATION robots

As part of its I.V. Room of the Future initiative to cooperate with other industry leaders, Health Robotics today announced the immediate availability of its revolutionary Virtual High-Availability Architecture (up to 99.99%), including state-of-the-art, virtualization compliant, cluster and fail-over, disaster recovery, and back-up solutions for its CytoCare and i.v.STATION robots [with future expansion to TPNstation when available], and its i.v.SOFT Workflow Engine for manual compounding.

7 Apr 2010

Major social science study to accompany Bovine TB BVDP

A major social science study to accompany the Government's Bovine TB Badger Vaccine Deployment Project, to be launched this summer [2010], will be led by a researcher from the University of the West of England, with colleagues from the Countryside and Community Research Institute, in collaboration with Exeter and Cardiff Universities, Drew Associates Limited, the Veterinary Laboratories Agency and the Food and Environment Research Agency.

7 Apr 2010

Antigens of both influenza B virus strains can improve influenza vaccines

Vaccines likely would work better in protecting children from flu if they included both strains of influenza B instead of just one, Saint Louis University research has found.

7 Apr 2010

Senator Grassley issues warning about 'phanton pharmacies' while Tampa officials arrest pharmacists on fraud charges

Senator Charles Grassley, R-Iowa, wrote a letter to Department of Health and Human Services Secretary Kathleen Sebelius this week saying federal officials have failed to stop the growing trend of "phantom pharmacies" that bill millions to Medicare in prescription drug costs then disappear, ABC News reports.

7 Apr 2010

Has the NHS procured too many swine flu shots?

Britain’s National Health Service (NHS) has nearly 34 million unused swine flu vaccines at present due to a drop in the number of cases and these vaccinations. A total 44 million shots were procured. 3.8 million of these unused shots will be sent to Africa via the World Health Organization to help them. Of the rest, 10.6m is already with GPs who will be ready to act if more people entitled to the jab come forward. But the remaining 23.6m will be held in reserve.

7 Apr 2010

Crucell, GSK sign agreement to develop 'second generation malaria vaccine'

Crucell, the Dutch biotechnology company, "said on Tuesday it had agreed with Britain's GlaxoSmithKline to jointly develop a malaria vaccine candidate, without disclosing financial details," Reuters reports (Gray-Block, 4/6).

7 Apr 2010

Avastin approval to drive ovarian cancer drug market to $1.5 billion in 2018

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the ovarian cancer drug market -- driven by the approval and rapid uptake of Roche/Genentech/Chugai's Avastin -- will more than triple from $449 million in 2008 to just under $1.5 billion in 2018 in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan.

7 Apr 2010

Ontario invests millions of dollars in universal flu vaccine campaign

The millions of dollars invested by the province of Ontario in its universal flu vaccine campaign saves lives and is a sensible investment, according to an economic analysis by a researcher at the University of Toronto and the University Health Network.

7 Apr 2010

$13,000 per year AIDS drugs Reyataz: AHF calls upon BMS to lower price

AIDS Healthcare Foundation (AHF) is pressing New York-based drug firm Bristol-Myers Squibb (BMS) to lower the price of its key AIDS drug, Reyataz—currently priced at over $13,000 per year—for lifesaving, but financially hard-hit AIDS Drug Assistance Programs (ADAPs) nationwide.

7 Apr 2010

FDA grants "Fast Track" designation for Genta’s advanced gastric cancer drug tesetaxel

Genta Incorporated today announced that the U.S. Food and Drug Administration (FDA) has granted the Company's request for "Fast Track" designation of tesetaxel for treatment of patients with advanced gastric cancer. Tesetaxel -- a late Phase 2 oncology product -- is the leading oral taxane currently in clinical development.

7 Apr 2010

FDA approves TachoSil adjunctive hemostatic agent for use in cardiovascular surgery

Baxter International Inc. and Nycomed today announced the U.S. Food and Drug Administration (FDA) approval of TachoSil (Absorbable Fibrin Sealant Patch) for use as an adjunct to hemostasis in cardiovascular surgery. TachoSil is the first and only adjunctive hemostatic agent available in the U.S. that combines a collagen patch with a coating of human coagulation factors.

From Baxter International Inc. 7 Apr 2010

Src can be most promising targets for cancer therapy

Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.

6 Apr 2010

OICR invests $415,000 to develop radiolabelled insulin probe for early detection of breast cancer

Dr. Tom Hudson, President and Scientific Director of the Ontario Institute for Cancer Research today announced an investment of $415,000 towards the development of a radiolabelled insulin probe for the early detection of breast cancer.

6 Apr 2010

PS-targeting antibodies can block HIV virus from entering into certain blood cells

Peregrine Pharmaceuticals, Inc. today announced the publication of data showing phosphatidylserine -targeting antibodies can block one of the key ways the AIDS virus gains entry into certain blood cells. The data were generated by scientists at Duke University as part of their ongoing AIDS vaccine research.

6 Apr 2010

Electronic nose may help identify asthma in patients: CHEST

New evidence shows that an "electronic nose" containing an array of gas sensors may have the ability to identify asthma in patients. Researchers from Italy compared the diagnostic performance of the electronic nose with lung function tests and fraction of exhaled nitric oxide in seven patients with asthma and seven healthy subjects.

6 Apr 2010

Par Pharmaceutical, sanofi-aventis resolve patent litigation case

Par Pharmaceutical Companies, Inc. today announced that it (and its subsidiary Par Pharmaceutical and development partner MN Pharmaceuticals of Turkey) has entered into a settlement agreement with sanofi-aventis that resolves patent litigation related to its generic version of sanofi's and Debiopharm's Eloxatin® (oxaliplatin injection) product, a drug used to treat colorectal cancer, in the U.S. District Court for the District of New Jersey.

6 Apr 2010

Prescription overdoses are second leading cause of unintentional deaths in US

"Unintentional poisoning is now the second leading cause of unintentional death in the US," reports Dr. Jeffrey H. Coben of West Virginia University School of Medicine in Morgantown. Among people 35 to 54 years old, unintentional poisoning surpassed motor vehicle crashes as the leading cause of unintentional death in 2005.

6 Apr 2010

Antiarrhythmic drug dronedarone less effective and causes fewer side effects

In a rigorous new review of the antiarrhythmic drug dronedarone (Multaq), researchers at the Cedars-Sinai Heart Institute conclude that the controversial drug is only modestly effective and has no clear safety benefits.

6 Apr 2010