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Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study.

20 Sep 2021

Development of a potential pan-variant aerosol to manage COVID-19

Researchers hypothesized that if APN01 could be directly introduced into the airways of an infected person, it could locally neutralize SARS-CoV-2.

19 Sep 2021

'Spice' users likely to experience more severe withdrawal symptoms, study finds

Research published today by psychologists at the University of Bath suggests that 'Spice' – which contains synthetic drugs originally designed to mimic the effects of cannabis – is more harmful than cannabis and that users are likely to experience more severe withdrawal symptoms when attempting to quit.

18 Sep 2021

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

A new study discusses the vaccination response in elderly who were vaccinated with one dose of the Pfizer vaccine 15 months after contracting COVID-19.

16 Sep 2021

How effective is the Johnson & Johnson COVID-19 vaccine?

A new study demonstrates the real-world efficacy of this vaccine, its stability over time, as well as its efficacy against the SARS-CoV-2 Delta variant.

16 Sep 2021

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

A new study describes a small molecule referred to as RG10 that may have potent antiviral activity against SARS-CoV-2 in human cells.

16 Sep 2021

Experts raise questions about routine use of surrogate endpoints for drug approvals

A growing number of drugs are being approved on the basis of indirect ('surrogate') measures that do not always reliably predict outcomes that matter most to patients, such as living longer or feeling better.

16 Sep 2021

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

In order to address these issues, scientists from Xitific LTD and IDEAPharma in the UK proposed a novel approach to the framework of immune correlates, built upon the previous research. The framework formulated by the authors was developed for the mRNA-based vaccinations but could be applied to the other variations.

16 Sep 2021

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

In a recent study, researchers investigate the possibility of using the thiazolide antiparasitic nitazoxanide for the treatment of COVID-19.

15 Sep 2021

Drug accumulation alters gut bacterial metabolism and composition

In a research paper recently published in the journal Nature by Klünemann et al. (September 8th, 2021), the interaction of 15 diverse drugs with 25 common strains of gut bacteria is investigated, revealing 70 bacteria-drug interactions that include 29 entirely novel mechanisms not yet reported.

15 Sep 2021

Study identifies broadly neutralizing antibody panel against SARS-like viruses

A recent study describes 40 broadly neutralizing antibodies from two individuals with a history of COVID-19 who were recently immunized against the virus.

13 Sep 2021

Research supports COVID booster vaccines for those aged 60 and over

Israeli researchers conducted an important study to determine if the Pfizer-BioNTech BNT162b2 vaccine had become less effective in preventing infection.

13 Sep 2021

Pharmacotherapy for alcohol use disorder is underutilized in Sweden, finds study

Only a minority of Swedes with alcohol use disorders are prescribed alcohol medication, a situation that has remained largely unchanged in the country since the mid-2000.

13 Sep 2021

International reference pricing could yield considerable savings for prescription drugs in the U.S.

Linking the cost of prescription drugs in the United States to the prices paid in other high-income nations could have reduced American spending for the drugs by at least half in 2020, according to a new RAND Corporation study.

12 Sep 2021

Study shows how oncology practices changed after durvalumab approval for unresectable stage III NSCLC patients

A study presented today at the IASLC 2021 World Conference on Lung Cancer suggests how oncology practices in the United States changed after 2018, when durvalumab became available for patients with unresectable Stage III non-small cell lung cancer.

12 Sep 2021

INCB, UNODC and WHO call on governments to facilitate access to controlled medicines in emergencies

Recognizing World Humanitarian Day 2021, the International Narcotics Control Board, the United Nations Office on Drugs and Crime and the World Health Organization once again call on governments to facilitate access to medicines containing controlled substances in emergency settings, including during pandemics and the increasing number of climate-related disasters.

10 Sep 2021

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Researchers in Australia have developed a coronavirus disease 2019 (COVID-9) vaccine that induced robust and long-lived humoral and cellular immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both young and aging mice.

8 Sep 2021

Pharmaceutical News

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

Development of a potential pan-variant aerosol to manage COVID-19

'Spice' users likely to experience more severe withdrawal symptoms, study finds

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

How effective is the Johnson & Johnson COVID-19 vaccine?

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

Experts raise questions about routine use of surrogate endpoints for drug approvals

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

Drug accumulation alters gut bacterial metabolism and composition

Study identifies broadly neutralizing antibody panel against SARS-like viruses

Research supports COVID booster vaccines for those aged 60 and over

Pharmacotherapy for alcohol use disorder is underutilized in Sweden, finds study

International reference pricing could yield considerable savings for prescription drugs in the U.S.

Study shows how oncology practices changed after durvalumab approval for unresectable stage III NSCLC patients

INCB, UNODC and WHO call on governments to facilitate access to controlled medicines in emergencies

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

New analysis provides timely information on disparities in vaccine confidence among US adults

Vesicular stomatitis virus-based COVID vaccines demonstrate potent antiviral efficacy against SARS-CoV-2 variants

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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