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New method of producing drug candidates may lead to better medicines in the future

A lot of our medicines and other bioactive drugs are based on chemical structures called "enantiomers"-- molecules that are mirror images of each other and are non-superimposable. Notable among them are chiral N,N-acetals contained in diuretic drugs like bendroflumethiazide and thiabutazide, used to treat high blood pressure and edema.

10 Feb 2021

FDA issues EUA for bamlanivimab and etesevimab for COVID-19 treatment

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for bamlanivimab and etesevimab administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) who test positive for SARS-CoV-2 and who are at high risk for progressing to severe COVID-19.

10 Feb 2021

Acceptance of COVID-19 vaccine has increased significantly under Biden administration

Under the Biden Administration, New Yorkers' acceptance of the Covid-19 vaccine has increased significantly. In September, 55% of residents reported they would take the vaccine when it became available and this January, 64% reported they would take it.

9 Feb 2021

COVID-19 vaccination associated with 3- to 5-fold reduction in viral load

Researchers in Israel report a reduction in viral load in vaccinated individuals.

9 Feb 2021

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

A new study provides direct evidence that the oligosaccharides attached to the viral surface spike protein are essential for viral infection, offering new approaches to preventive and therapeutic drugs.

9 Feb 2021

Commentary on severe allergic reaction to mRNA SARS-CoV-2 vaccines

A commentary by John M. Kelso, Division of Allergy, Asthma and Immunology, Scripps Clinic, published in the latest issue of the journal Vaccines, discusses anaphylactic reactions to these novel mRNA SARS-CoV-2/COVID-19 vaccines.

8 Feb 2021

$FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma$

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

Today, the U.S. Food and Drug Administration approved Breyanzi (lisocabtagene maraleucel), a cell-based gene therapy to treat adult patients with certain types of large B-cell lymphoma who have not responded to, or who have relapsed after, at least two other types of systemic treatment.

5 Feb 2021

SGD Pharma Takes Lead in Sustainability, Awarded Platinum EcoVadis Rating for The First Time

SGD Pharma, a leading supplier of glass primary packaging in the pharmaceutical industry, has been awarded a ‘platinum’ rating by EcoVadis, positioning it in the top 1% of all companies rated worldwide.

From SGD Pharma 5 Feb 2021

FDA schedules meeting to discuss EUA request for Janssen’s COVID-19 vaccine

The U.S. Food and Drug Administration has scheduled a meeting of its Vaccines and Related Biological Products Advisory Committee (VRBPAC) on Feb. 26, 2021, to discuss the request for emergency use authorization (EUA) for a COVID-19 vaccine from Janssen Biotech Inc.

5 Feb 2021

Study calls for continuous monitoring of dark web marketplaces in view of vaccines shortage

New research carried out by City data scientist, Dr. Andrea Baronchelli, and colleagues, into the dark web marketplace (DWM) trade in products related to COVID-19, has revealed the need for the continuous monitoring of dark web marketplaces (DWMs), especially in light of the current shortage and availability of coronavirus vaccines.

5 Feb 2021

Study: Black people are less likely to live near hospitals that administer COVID-19 vaccines

Researchers at the University of Pittsburgh School of Pharmacy and West Health Policy Center found that in many parts of the country, Black people are less likely than white people to live near a pharmacy, clinic, hospital or health center that can administer COVID-19 vaccines.

5 Feb 2021

Pharmacologist lays out a plan to improve the equity of drug development

In a new perspective piece published in the Feb. 5 issue of Science, pharmacologist Namandje Bumpus, Ph.D. -- who recently became the first African American woman to head a Johns Hopkins University School of Medicine department, and is the only African American woman leading a pharmacology department in the country -- outlines the molecular origins for differences in how well certain drugs work among distinct populations.

4 Feb 2021

Researchers develop thermostable RNA vaccine delivery platform

A new study describes the production of a new RNA vaccine delivery system that promises greater ease of storage and distribution. This could help boost vaccination rates in regions without adequate infrastructure for low-temperature storage.

4 Feb 2021

South African SARS-CoV-2 variant neutralized by two Chinese vaccines in case study

A new study offers some reassuring findings, reporting the successful neutralization of the South African SARS-CoV-2 variant of concern (VOC) 501Y.V2 by two vaccines developed in China.

4 Feb 2021

Pfizer vaccine and Eli Lilly monoclonal antibodies successfully neutralize SARS-CoV-2 UK variant, finds study

A new study reports the underlying basis of increased transmissibility in the N501Y UK variant and provides reassuring data on the efficacy of the Pfizer vaccine and Eli Lilly monoclonal antibodies in neutralizing it.

4 Feb 2021

Study: Nalfurafine drug can help treat spinal morphine-induced itch in pregnant women

For years, many pregnant women and surgery patients have suffered from chronic itching when they get spinal or epidural morphine to reduce pain.

4 Feb 2021

Study identifies gap between theory and reality of dispensing medication

A study published in the journal Applied Ergonomics compared the standardized processes set out for community pharmacists to follow when dispending medication to what happens in reality. A gap was revealed and researchers also looked at the reasons for this.

4 Feb 2021

Pharmaceutical News

New method of producing drug candidates may lead to better medicines in the future

FDA issues EUA for bamlanivimab and etesevimab for COVID-19 treatment

Acceptance of COVID-19 vaccine has increased significantly under Biden administration

COVID-19 vaccination associated with 3- to 5-fold reduction in viral load

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

Commentary on severe allergic reaction to mRNA SARS-CoV-2 vaccines

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

SGD Pharma Takes Lead in Sustainability, Awarded Platinum EcoVadis Rating for The First Time

FDA schedules meeting to discuss EUA request for Janssen’s COVID-19 vaccine

Study calls for continuous monitoring of dark web marketplaces in view of vaccines shortage

Study: Black people are less likely to live near hospitals that administer COVID-19 vaccines

Pharmacologist lays out a plan to improve the equity of drug development

Researchers develop thermostable RNA vaccine delivery platform

South African SARS-CoV-2 variant neutralized by two Chinese vaccines in case study

Pfizer vaccine and Eli Lilly monoclonal antibodies successfully neutralize SARS-CoV-2 UK variant, finds study

Study: Nalfurafine drug can help treat spinal morphine-induced itch in pregnant women

Study identifies gap between theory and reality of dispensing medication

European biotech companies rely on AI to deliver COVID-19 vaccine

Rescheduling drugs can reduce use as well as the dangers, study finds

New drug cocktail offers hope to patients with highly drug-resistant tuberculosis

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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