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New automated system may reduce opioid misuse

After more than 1,000 orthopedic procedures at a city health system, roughly 61 percent of the opioids prescribed to patients went unused, according to new research.

18 Feb 2021

Rebate systems may hamper patient access to drugs

Pharmaceutical manufacturers and national authorities often negotiate secret rebates when determining drug prices. A UZH study shows that these rebate systems may hamper patient access to drugs. In the medium term, this practice can even lead to increasing drug prices.

17 Feb 2021

$Study investigates fracture-associated drug use among long-term care residents$

Study investigates fracture-associated drug use among long-term care residents

Findings from a new Geisel-led study, published in the Journal of General Internal Medicine, reveal that there is substantial variation across different regions of the country in the intensity of fracture-associated drug (FAD) use among long-term care facility residents, and that areas with greater use of these prescription drugs experience higher hip fracture rates.

17 Feb 2021

Study: Body produces large amounts of GDF15 hormone during extended bouts of vigorous exercise

A drug that helps us to eat less could help the more than 650 million people around the world who live with obesity.

17 Feb 2021

Rich nations should not engage in "vaccine nationalism”, says Binghamton University expert

Rich nations should not engage in "vaccine nationalism" and keep the COVID-19 vaccine to themselves when poorer nations need them, according to Nicole Hassoun, professor of philosophy at Binghamton University, State University of New York. Hassoun's paper, "Against Vaccine Nationalism," was published in the Journal of Medical Ethics.

17 Feb 2021

Pan-coronavirus vaccine needed to deal SARS-CoV-2 variants

In an article, published on the JAMA Network and written by health experts, including Dr. Anthony Fauci, American physician-scientist and immunologist serving as the director of the National Institute of Allergy and Infectious Diseases, the authors discuss the need for a pan-coronavirus vaccine, which can protect against most or all variants of SARS-CoV-2.

16 Feb 2021

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and develop prediabetes and hyperinsulemia?

15 Feb 2021

Study: Cytoglobin drug could delay the progression of liver fibrosis in mice

Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice.

15 Feb 2021

Can Pfizer and Moderna end the pandemic by sharing their vaccine designs? It’s not that simple

Vaccine makers Pfizer and Moderna earned praise for creating highly effective covid-19 vaccines in record time.

15 Feb 2021

A machine learning approach to identify drugs that could be repurposed to fight COVID-19

When the Covid-19 pandemic struck in early 2020, doctors and researchers rushed to find effective treatments. There was little time to spare.

15 Feb 2021

Immunomodulatory drugs improve the success rate of cancer therapies

Immunomodulatory drugs, including the Contergan derivatives lenalidomide and pomalidomide, have significantly improved the therapy of hematologic malignancies such as multiple myeloma.

15 Feb 2021

Study: Aspirin should be favored to prevent blood clots in children after complex heart surgery

Aspirin should be favored over warfarin to prevent blood clotting in children who undergo a surgery that replumbs their hearts, according to a new study.

14 Feb 2021

Poor and terminally ill Mexicans have less chance to get opioids intended for palliative care

If you're poor and terminally ill in southern Mexico, there's far less chance you'll get the painkillers you need for palliative care than your cousins in more prosperous regions, particularly those pharmacy-rich areas along Mexico-U.S. border, say UCLA researchers and colleagues who studied opioid dispensing levels across the country.

13 Feb 2021

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Today, the U.S. Food and Drug Administration approved Cosela (trilaciclib) as the first therapy in its class to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer.

13 Feb 2021

How effective has the COVID-19 vaccination program been in Israel?

Using publicly available coronavirus disease 2019 (COVID-19) data from Israel, a study suggests the BioNTech-Pfizer BNT162b2 vaccine is proving highly effective in the real world.

12 Feb 2021

People previously infected with COVID-19 respond strongly to one dose of Pfizer vaccine

Although clinical trial data are encouraging, real-world evidence with regard to the COVID-19 vaccine remains scarce. In particular, response to the vaccine among those previously infected with SARS-CoV-2 is still not completely understood.

12 Feb 2021

Opioid use during pregnancy can cause long-lasting impairment in the infant's brain

As the number of pregnant women using opioid drugs continues to rise, questions have been raised about the long-term health effects on children exposed to these drugs in the womb.

12 Feb 2021

New gut microbiome-based approach may have translational potential for cancer immunotherapy

Scientists from Nanjing University and the University of Macau have devised a new approach to extend the survival of transplanted probiotics in vivo, enhancing the efficacy of cancer chemo-/immunotherapies in mice.

11 Feb 2021

MD Anderson and Mirati Therapeutics collaborate to expand evaluation of potent KRAS inhibitors

The University of Texas MD Anderson Cancer Center and Mirati Therapeutics, Inc. today announced a strategic research and development collaboration to expand the evaluation of Mirati's two investigational small molecules, potent and selective KRAS inhibitors - adagrasib (MRTX849), a G12C inhibitor in clinical development, and MRTX1133, a G12D inhibitor in preclinical development, as monotherapy and in combination with other agents - which target two of the most frequent KRAS mutations in cancer.

10 Feb 2021

Orally administered experimental drug halts SARS-CoV-2 replication, prevents infection

Publishing their work in Nature, scientists at the UNC School of Medicine and UNC Gillings School of Global Public Health found that the orally administered experimental drug EIDD-2801 halts SARS-CoV-2 replication and prevents infection of human cells in a new in vivo lab model containing human lung tissue.

10 Feb 2021

Pharmaceutical News

New automated system may reduce opioid misuse

Rebate systems may hamper patient access to drugs

Study investigates fracture-associated drug use among long-term care residents

Study: Body produces large amounts of GDF15 hormone during extended bouts of vigorous exercise

Rich nations should not engage in "vaccine nationalism”, says Binghamton University expert

Pan-coronavirus vaccine needed to deal SARS-CoV-2 variants

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Study: Cytoglobin drug could delay the progression of liver fibrosis in mice

Can Pfizer and Moderna end the pandemic by sharing their vaccine designs? It’s not that simple

A machine learning approach to identify drugs that could be repurposed to fight COVID-19

Immunomodulatory drugs improve the success rate of cancer therapies

Study: Aspirin should be favored to prevent blood clots in children after complex heart surgery

Poor and terminally ill Mexicans have less chance to get opioids intended for palliative care

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

How effective has the COVID-19 vaccination program been in Israel?

People previously infected with COVID-19 respond strongly to one dose of Pfizer vaccine

Opioid use during pregnancy can cause long-lasting impairment in the infant's brain

New gut microbiome-based approach may have translational potential for cancer immunotherapy

MD Anderson and Mirati Therapeutics collaborate to expand evaluation of potent KRAS inhibitors

Orally administered experimental drug halts SARS-CoV-2 replication, prevents infection

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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