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HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs.

1 Dec 2020

Chloroquine/hydroxychloroquine could treat COVID-19 infection

The recent serious outbreak of Covid19 has affected (November 13, 2020) 53,796,098 people worldwide, resulting in 37,555,669 recovered, 1,310,250 deaths, and a large number of open cases.

1 Dec 2020

New book serves as reference guide for CNS drugs

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set Medicinal Chemistry for Pharmacy Students serves as a reference guide to pharmacists on aspects of the chemical basis of drug action.

1 Dec 2020

Researchers develop recommendations for ethical handling of big data on opioid use disorder

The use of big data to address the opioid epidemic in Massachusetts poses ethical concerns that could undermine its benefits without clear governance guidelines that protect and respect patients and society, a University of Massachusetts Amherst study concludes.

1 Dec 2020

How pharma money colors Operation Warp Speed’s quest to defeat COVID

April 16 was a big day for Moderna, a Massachusetts biotech company on the verge of becoming a front-runner in the U.S. government's race for a coronavirus vaccine. It had received roughly half a billion dollars in federal funding to develop a COVID shot that might be used on millions of Americans.

30 Nov 2020

Researchers highlight potential advantages of mucosal vaccine

Anyone who has undergone a nasal swab or saliva test for COVID-19 knows that the virus is most easily detected in the nose and mouth.

30 Nov 2020

New drug lures stem cells to damaged tissue, improves treatment efficacy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a drug that can lure stem cells to damaged tissue and improve treatment efficacy--a scientific first and major advance for the field of regenerative medicine.

25 Nov 2020

Researchers describe a simple, inexpensive way to measure drug dissolution

When you take a time-release drug, you count on it doing what the package says: release the drug slowly into your bloodstream to provide benefits over the specified period of time.

25 Nov 2020

Study: 58% of adults over 50 are willing to receive COVID-19 vaccination

Once enough people receive effective vaccines against the novel coronavirus, experts say, the end of the pandemic may be in sight. But a new poll of older adults - one of the highest-priority groups for vaccination - suggests an uphill climb lies ahead to reach that goal.

24 Nov 2020

Study: Aprotinin can inhibit virus replication by preventing SARS-CoV2 entry into host cells

The surface of the SARS-CoV-2 virus is studded with spike proteins. The virus needs these in order to dock onto proteins (ACE2 receptors) on the surface of the host cell.

24 Nov 2020

$Z-drugs can increase risk of falls, fractures, and stroke in dementia patients$

Z-drugs can increase risk of falls, fractures, and stroke in dementia patients

Strong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia - according to research from the University of East Anglia.

24 Nov 2020

New technology can provide immunization against infectious diseases

A single-use, self-administered microneedle technology developed by UConn faculty to provide immunization against infectious diseases has recently been validated by preclinical research trials.

23 Nov 2020

Unique training program is bolstering Canada’s capacity to manufacture novel biotherapeutics

As COVID-19 highlights the urgent need to increase vaccine manufacturing around the world, a unique training program is bolstering Canada's capacity to manufacture vaccines, as well as viral immunotherapies for cancer and other emerging biotherapeutics.

23 Nov 2020

FDA expands approved indication for influenza treatment to include post-exposure prevention

Today, the U.S. Food and Drug Administration expanded the approved indication for Xofluza (baloxavir marboxil) to include post-exposure prevention of influenza (flu) for patients 12 years of age and older after contact with an individual who has the flu.

23 Nov 2020

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

The U.S. Food and Drug Administration has scheduled a meeting of its Vaccines and Related Biological Products Advisory Committee (VRBPAC) on Dec. 10 to discuss the request for emergency use authorization (EUA) of a COVID-19 vaccine from Pfizer, Inc. in partnership with BioNTech Manufacturing GmbH.

23 Nov 2020