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New paper defines strategy for developing effective vaccines for Lyme disease

There is no effective vaccine currently available to prevent Lyme disease in humans.

17 Oct 2019

Rapamycin is more effective at slowing down aging, says researcher

The scientist discusses several reasons, including fear of the actual and fictional side effects of rapamycin, everolimus and other clinically-approved drugs, arguing that no real side effects preclude their use as anti-aging drugs today.

17 Oct 2019

International system can provide practical guideline on cannabis use, say researchers

Despite widespread use of the drug around the world and increasing moves to legalise its sale for recreational consumption, standard units - which have been commonplace for alcohol for many years - have never been adopted in health guidelines for cannabis.

16 Oct 2019

New initiative aims to use artificial intelligence to identify early drug candidates

Insilico Medicine, in collaboration with ChemDiv, Inc., launched a drug discovery initiative that aims to use the power of artificial intelligence for screening chemistry space with newly designed compounds.

16 Oct 2019

Machine learning system may offer warnings about negative side effects of drug-drug interactions

The more medications a patient takes, the greater the likelihood that interactions between those drugs could trigger negative side effects, including long-term organ damage and even death.

15 Oct 2019

Study explains why some people who take heart medication develop sore, aching muscles

A study from McMaster University has found a potential mechanism explaining why some people who take drugs to lower their cholesterol develop sore, aching muscles.

15 Oct 2019

How Is Ophthalmology Changing To Meet New Challenges?

Ophthalmology, a highly dynamic space in vision loss and age-related eye diseases with approximately 1.3 billion people living with vision impairment.

From Santen Pharmaceutical Co., Ltd. 15 Oct 2019

St George Street Capital signs agreement with AstraZeneca to develop two compounds in the clinic

St George Street Capital, a UK registered charity, has signed a license agreement with AstraZeneca to develop two compounds in the clinic: one for idiopathic male infertility, and the other for renal transplant rejection. The agreement enables additional compounds to be added in the future.

From AstraZeneca 14 Oct 2019

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate (ADC) payloads, today announced data verifying the favorable toxicity profile and potent efficacy of its Pyridinobenzodiazepine (PDD) ADC payload platform in tumor cell models.

14 Oct 2019

California’s new transparency law reveals steep rise in wholesale drug prices

Drugmakers fought hard against California's groundbreaking drug price transparency law, passed in 2017. Now, state health officials have released their first report on the price hikes those drug companies sought to shield.

14 Oct 2019

Ophthalmologists find more evidence linking common bladder drug to retinal conditions

A drug widely prescribed for a bladder condition for decades, now appears to be toxic to the retina, the light sensing tissue at the back of the eye that allows us to see.

14 Oct 2019

Impress your boss with this course

In this webinar, Dr. Michael W. Dong, Pittcon Short Course Instructor, will review best practices, short cuts, and tricks-of-the-trade to help pharmaceutical and other scientists to become more successful in developing effective HPLC methods (potency and ICH-compliant stability-indicating assays) using method templates and universal generic gradient methods.

From Pittcon 14 Oct 2019

Caution urged in reducing opioids for pain

After years and decades in which healthcare providers were freely prescribing opiates for all sorts of painful conditions, the US Centers for Disease Control and Prevention (CDC) published guidelines to help bring down opioid prescription rates and with them, addiction and overdose-related death rates. Though these were not binding, they urged physicians to be cautious in dealing with opioids when prescribing for pain.

13 Oct 2019

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models.

11 Oct 2019

RTKI drugs may not significantly improve survival rates of patients during radiotherapy

Taking certain cancer-fighting drugs while undergoing radiation therapy may not increase survival for patients, but may, instead, increase side effects, according to a team of researchers. The drugs, however, may be beneficial for patients who are not undergoing radiation therapy.

10 Oct 2019

Vaccine against gastrin may slow spread of pancreatic cancer

New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.

10 Oct 2019

‘Sticky’ gene may boost the nerve calming effects of Valium

Between 1999 and 2017, the United States experienced a 10-fold increase in the number of people who died from overdoses of Valium and other benzodiazepines.

10 Oct 2019

Scientists show how the immune system reacts to Ebola vaccine

Following the dramatic Ebola epidemic in West Africa from 2013 to 2016, viral infections have spread in the Democratic Republic of Congo since 2018. Since then, more than 2,100 deaths have been reported and the number of victims and new infections increases daily.

10 Oct 2019

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

Insilico Medicine, a company developing an end-to-end drug discovery pipeline utilizing the latest advances in deep learning, has entered into a two-program research collaboration agreement with Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd..

9 Oct 2019

New analysis examines the darknet's opioid purchases

U.S. overdose deaths attributed to synthetic opioids, such as fentanyl, have increased from under 3,000 in 2013 to nearly 20,000 in 2016, making up half of all opioid-related overdose deaths.

9 Oct 2019

Pharmaceutical News

New paper defines strategy for developing effective vaccines for Lyme disease

Rapamycin is more effective at slowing down aging, says researcher

International system can provide practical guideline on cannabis use, say researchers

New initiative aims to use artificial intelligence to identify early drug candidates

Machine learning system may offer warnings about negative side effects of drug-drug interactions

Study explains why some people who take heart medication develop sore, aching muscles

How Is Ophthalmology Changing To Meet New Challenges?

St George Street Capital signs agreement with AstraZeneca to develop two compounds in the clinic

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

California’s new transparency law reveals steep rise in wholesale drug prices

Ophthalmologists find more evidence linking common bladder drug to retinal conditions

Impress your boss with this course

Caution urged in reducing opioids for pain

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

RTKI drugs may not significantly improve survival rates of patients during radiotherapy

Vaccine against gastrin may slow spread of pancreatic cancer

‘Sticky’ gene may boost the nerve calming effects of Valium

Scientists show how the immune system reacts to Ebola vaccine

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

New analysis examines the darknet's opioid purchases

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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