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Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

Novel antibodies could provide a universal flu vaccine

Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of viral cell surface antigen called neuraminidase (NA) that is necessary for viral replication.

28 Oct 2019

Work in progress on medicine for treatment of ulcerative colitis

IKBFU center for clinical research scientists have participated in the international VARSITY clinical research. It's the world's first research aimed at finding the most effective drug among anti-inflammatory ones for the treatment of ulcerative colitis.

28 Oct 2019

Cancer drug may delay progression of bone and other myeloma-related organ damage

The largest randomized trial in asymptomatic patients with smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of bone and other myeloma-related organ damage.

28 Oct 2019

Molecular mechanisms involved in Pixantrone's interactions with cancer DNA discovered

Recently, a drug named Pixantrone (PIX) was developed, which is far less damaging to the heart than previous, less advanced compounds. PIX is now used to treat cancers including non-Hodgkin's lymphoma and leukaemia, but a detailed knowledge of the molecular processes it uses to destroy cancer cells has been lacking so far.

28 Oct 2019

New injectable formula to treat joint inflammation has sustained effect for ten days

Thanks to a new injectable formula, Brazilian researchers have succeeded in enhancing the efficacy and prolonging the duration of action of a drug commonly used to treat joint inflammation.

25 Oct 2019

Study compares safety and effectiveness of first-line antihypertensive drug classes

For those with extremely high blood pressure, or hypertension, there are many initial medication options -- so many that it can be hard to know which one to use.

25 Oct 2019

New ADA guideline: Antibiotics not recommended for toothaches

The American Dental Association announced today a new guideline indicating that in most cases, antibiotics are not recommended for toothaches.

25 Oct 2019

First-line antihypertensives may not be most effective, study shows

Thiazide diuretics demonstrate better effectiveness and cause fewer side effects than ACE inhibitors as first-line antihypertensive drugs, according to a report published Oct. 24 in The Lancet.

25 Oct 2019

Most popular first-line treatment for hypertension may be less effective than alternative drugs

A new multinational study shows that the most popular first-line treatment for hypertension is less effective and has more side effects than an alternative that's prescribed much less often.

25 Oct 2019

NIA-funded study to examine overall benefits and risks of statins in older adults

The National Institute on Aging has funded a major study to examine the overall benefits and risks of cholesterol-lowering drugs known as statins in adults age 75 or older without cardiovascular disease.

23 Oct 2019

Emory researchers awarded NIAID contract to develop better drug against influenza

With the flu killing an average of 20,000 people annually in the United States and posing the larger threat of global pandemics, Emory University's strides in influenza research carry the hope of saving lives here and abroad.

23 Oct 2019

Highest anxiety and sleeping pill prescription rates in deprived areas of England

The poorest and most socially deprived areas in England have the highest rates of prescription for benzodiazepines and Z-drugs, according to a new University of Warwick study published in the journal Family Practice on October 22, 2019.

23 Oct 2019

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

A research team from the School of Chinese Medicine at Hong Kong Baptist University has successfully developed a novel aptamer, i.e. a single-stranded piece of DNA, for the treatment of osteogenesis imperfecta (OI) with the aid of artificial intelligence (AI) technology.

23 Oct 2019

New $30M contract signed to accelerate TB vaccine development across the country

Tuberculosis (TB) is the number-one cause of death from an infectious disease in the world: In 2017, the most recent data available, 10 million people developed TB and 1.6 million died.

23 Oct 2019

Researchers map global use of illicit drugs via wastewater samples

A seven-year project monitoring illicit drug use in 37 countries via wastewater samples shows that cocaine use was skyrocketing in Europe in 2017 and Australia had a serious problem with methamphetamine.

23 Oct 2019

Study finds little evidence on effectiveness of common antidepressant in autism spectrum disorders

A new study has found there is little evidence that a widely used antidepressant is effective at reducing obsessive compulsive behaviours in children and adolescents with autism spectrum disorders.

23 Oct 2019

Anti-arthritis drug can stop tuberculosis bacillus from infecting blood stem cells

Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells.

23 Oct 2019

Half the drugs in use damage gut bacteria, says new study

A startling presentation at UEG Week 2019, in Barcelona, reveals that the gut microbiome is at high risk for damage each time we use a drug from one or more of 18 commonly used groups. The effects may range from changes in the relative proportions of different beneficial and potentially harmful species to alterations in the cellular metabolism of the bacteria themselves.

23 Oct 2019

1 in 8 pharmacies in the U.S. affected by closures

In a report published in JAMA Internal Medicine, researchers from the University of Illinois at Chicago found that despite an overall increase in the number of pharmacies in the U.S. from 2009 to 2015, one in eight pharmacies, or 9,654, had closed during this period.

21 Oct 2019

Pharmaceutical News

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Novel antibodies could provide a universal flu vaccine

Work in progress on medicine for treatment of ulcerative colitis

Cancer drug may delay progression of bone and other myeloma-related organ damage

Molecular mechanisms involved in Pixantrone's interactions with cancer DNA discovered

New injectable formula to treat joint inflammation has sustained effect for ten days

Study compares safety and effectiveness of first-line antihypertensive drug classes

New ADA guideline: Antibiotics not recommended for toothaches

First-line antihypertensives may not be most effective, study shows

Most popular first-line treatment for hypertension may be less effective than alternative drugs

NIA-funded study to examine overall benefits and risks of statins in older adults

Emory researchers awarded NIAID contract to develop better drug against influenza

Highest anxiety and sleeping pill prescription rates in deprived areas of England

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

New $30M contract signed to accelerate TB vaccine development across the country

Researchers map global use of illicit drugs via wastewater samples

Study finds little evidence on effectiveness of common antidepressant in autism spectrum disorders

Anti-arthritis drug can stop tuberculosis bacillus from infecting blood stem cells

Half the drugs in use damage gut bacteria, says new study

1 in 8 pharmacies in the U.S. affected by closures

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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