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Breakthrough discovery in HIV research opens path to new, better therapies

New research on the human immunodeficiency virus (HIV) structure has revealed a promising novel drug target for treating it.

23 Apr 2020

Researchers show how drug particles spread around crime labs

When two scientists from the National Institute of Standards and Technology (NIST) brought black lights and glow powder into the Maryland State Police crime lab, they weren't setting up a laser tag studio or nightclub.

23 Apr 2020

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Oncotarget Volume 11 Issue 16 showed that the sensitivity of H1299 and A549 cells to concomitant treatment with PAC and WFA was greater than that of either PAC or WFA alone.

23 Apr 2020

Series of rare side effects underscores the need to track targeted anti-cancer drugs

Tejas Patil, MD, is a medical oncologist. Lisa Ferrigno, MD, MPH, FACS, is a trauma surgeon. Working with lung cancer patients at University of Colorado Cancer Center, they both, independently, noticed something strange:

23 Apr 2020

Nasal spray containing esketamine could provide an effective treatment for depression

Depression and long-term stress have been demonstrated to cause changes in the brain which offer a partial explanation for depressive moods, apathy, memory difficulties and other symptoms commonly associated with depression.

22 Apr 2020

Nanoengineers are using plant virus to develop COVID-19 vaccine

Nanoengineers at the University of California San Diego are working on a COVID-19 vaccine using an unconventional candidate: a plant virus.

22 Apr 2020

Amid pandemic, FDA seizes cheaper drugs from Canada

The Food and Drug Administration in the past month has stepped up seizures of prescription drugs being sent to American customers from pharmacies in Canada and other countries, according to operators of stores in Florida that facilitate the transactions.

20 Apr 2020

A promising antiviral drug to fight COVID-19 pandemic

COVID-19 patients in a clinical trial at Houston Methodist Hospital are responding quickly to the antiviral drug Remdesivir. The trial's criteria allows for the treatment of patients early in their clinical course and, in some cases, at times where they might have otherwise been intubated.

17 Apr 2020

New computational model shows how psilocybin affects brain activity

Interest in research into the effects of psilocybin, a psychedelic drug, has increased significantly in recent years due to its promising therapeutic effects in neuropsychiatric disorders such as depression, anxiety and addiction.

17 Apr 2020

Alzheimer's patients may need modified dosing regimens for selected drugs

Patients with Alzheimer's disease are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia.

15 Apr 2020

Research Suggests Widespread Opioid Overprescribing has Lead to Opioid Epidemic

Research indicates that widespread opioid overprescribing contributed to the opioid epidemic.

15 Apr 2020

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

Amid the coronavirus disease (COVID-19) global pandemic that is infecting millions of people across the globe, hope sparks as the World Health Organization (WHO) reports that seventy vaccination trials for the novel coronavirus are underway, with three already at the human trial stage.

14 Apr 2020

Super-charging production of drugs for COVID-19

Researchers are ramping up production of a promising drug that has proven effective in obliterating SARS-CoV in cellular cultures. The team hopes that the drug might also be effective in the fight against SARS's close genetic cousin, the novel coronavirus (COVID-19).

13 Apr 2020

Cost of ‘repurposing’ existing drugs to treat COVID-19

The paper looks at repurposed drugs that might demonstrate efficacy against COVID-19, and if they could be manufactured profitably at very low costs to ensure affordable access to vital treatments for COVID-19 at low prices globally.

13 Apr 2020

FDA approves first-ever treatment for patients with inoperable plexiform neurofibromas

The U.S. Food and Drug Administration has approved Koselugo (selumetinib) for use in patients with inoperable plexiform neurofibromas, a common manifestation in the disease neurofibromatosis type one (NF1).

13 Apr 2020

Promising COVID-19 drug treatments identified with new screening strategies

As scientists across the world race to find a pharmacological cure for coronavirus disease (COVID-19), an international research group has analyzed more than 10 thousand different compounds and identified six potential candidates, publishing their results in the leading scientific journal Nature.

12 Apr 2020

Potential harms associated with some drugs used for treating COVID-19 patients

Chloroquine, hydroxychloroquine and azithromycin are being used to treat and prevent COVID-19 despite weak evidence for effectiveness, and physicians and patients should be aware of the drugs' potentially serious adverse events, states a review in CMAJ.

8 Apr 2020