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Researchers modify nanoparticles to improve their uptake in gastrointestinal tract

Nanoparticles show great promise as diagnostic tools and drug delivery agents. The tiny particles, which scientists can modify with drugs, dyes or targeting molecules, can travel in the circulation and squeeze through small spaces into cells and tissues.

9 Aug 2018

Researchers study whether chemotherapy could be encased in milk particles

You can't eat chemotherapy. That's because your digestive system breaks down the molecules you eat into smaller pieces that can be absorbed through the gut into the bloodstream.

9 Aug 2018

Pharmacy-made pain creams flagged on fears of Medicare fraud and risk

Medicare pays hundreds of millions of dollars each year for prescription creams, gels and lotions made-to-order by pharmacies — mainly as pain treatments. But a new report finds that officials are concerned about possible fraud and patient safety risks from products made at nearly a quarter of the pharmacies that fill the bulk of those prescriptions.

9 Aug 2018

Scientists identify drug that could reverse pulmonary arterial hypertension

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension, a severe lung disease with a five-year survival rate of 50 percent.

9 Aug 2018

FDA approves potassium chloride oral solution as first generic drug to receive CGT designation

The U.S. Food and Drug Administration today approved several strengths of potassium chloride oral solution as the first generic drugs to receive a Competitive Generic Therapy designation.

9 Aug 2018

New review examines potential of medicinal cannabis to help treat intractable epilepsy

A new British Journal of Clinical Pharmacology review examines the potential of medicinal cannabis--or medical marijuana--for helping patients with intractable epilepsy, in which seizures fail to come under control with standard anticonvulsant treatment.

8 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

Mandatory vaccinations for children stopped in Italy

The Italian government has removed the necessity for all children to be vaccinated against 10 important infectious diseases before they can join school or day care. This has shocked and angered the medical and scientific community.

7 Aug 2018

Taking cholesterol-busting pills can effectively treat brutal PAP

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis, and they show taking cholesterol-busting pills called statins can effectively treat the disease.

7 Aug 2018

Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

Extended-release naltrexone -- an injection that decreases heavy drinking in the general population when taken in conjunction with counseling -- appears to help HIV-positive individuals reduce their number of heavy drinking days too, say Yale researchers.

7 Aug 2018

Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpentine.

7 Aug 2018

Injecting vasoactive intestinal peptide into the eye enhances corneal graft survival

A new study in the American Journal of Pathology reports for the first time that injection of neuropeptide vasoactive intestinal peptide directly into the eye of mice enhanced corneal graft survival.

7 Aug 2018

Doxorubicin drug causes heart toxicity by disrupting the immune system

Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure.

7 Aug 2018

Medicaid expansion increases access to diabetes treatment

Prescriptions for diabetes medications increased in the first two years after states expanded eligibility for Medicaid as part of the Affordable Care Act, compared to states that didn't expand Medicaid.

7 Aug 2018

WVU researchers examine safety of Suboxone use in opioid-dependent pregnant women

Medications that physicians have traditionally prescribed to treat opioid use disorders-such as methadone and Subutex-can be misused by taking them in larger amounts than prescribed or by injecting them.

7 Aug 2018

FDA issues scientific recommendations to encourage development of novel drugs for treatment of OUD

The U.S. Food and Drug Administration today issued new scientific recommendations aimed at encouraging more widespread innovation and development of novel medication-assisted treatment drugs for the treatment of opioid use disorder.

7 Aug 2018

Medicaid expansion making diabetes meds more accessible to poor, study shows

Low-income people with diabetes are better able to afford their medications and manage their disease in states that expanded Medicaid under the Affordable Care Act, a new study suggests.

6 Aug 2018

EMA grants orphan designation to selumetinib for treatment of neurofibromatosis type 1

AstraZeneca and Merck, known as MSD outside the U.S. and Canada, today announced that the European Medicines Agency (EMA) has granted orphan designation to selumetinib, a MEK 1/2 inhibitor, for the treatment of neurofibromatosis type 1 (NF1).

3 Aug 2018

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

Otsuka’s JINARC approved for treatment of patients with CKD stage 4 ADPKD

Otsuka Pharmaceutical Europe Ltd. today announced that the European Commission has approved an extension of indication for JINARC to include adult patients with CKD stage 4 Autosomal Dominant Polycystic Kidney Disease

2 Aug 2018

Pharmaceutical News

Researchers modify nanoparticles to improve their uptake in gastrointestinal tract

Researchers study whether chemotherapy could be encased in milk particles

Pharmacy-made pain creams flagged on fears of Medicare fraud and risk

Scientists identify drug that could reverse pulmonary arterial hypertension

FDA approves potassium chloride oral solution as first generic drug to receive CGT designation

New review examines potential of medicinal cannabis to help treat intractable epilepsy

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

Mandatory vaccinations for children stopped in Italy

Taking cholesterol-busting pills can effectively treat brutal PAP

Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

Scientists create new tool to precisely control 3D architecture of linkages in drugs

Injecting vasoactive intestinal peptide into the eye enhances corneal graft survival

Doxorubicin drug causes heart toxicity by disrupting the immune system

Medicaid expansion increases access to diabetes treatment

WVU researchers examine safety of Suboxone use in opioid-dependent pregnant women

FDA issues scientific recommendations to encourage development of novel drugs for treatment of OUD

Medicaid expansion making diabetes meds more accessible to poor, study shows

EMA grants orphan designation to selumetinib for treatment of neurofibromatosis type 1

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Otsuka’s JINARC approved for treatment of patients with CKD stage 4 ADPKD

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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