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High out-of-pocket costs act as barrier to potentially life-saving cancer treatments

Sticker shock may be leading many insured Americans with cancer to forego treatment with a wide range of oral cancer drugs, suggests a study published online this week in the Journal of Clinical Oncology.

20 Dec 2017

UTA researchers analyze challenges in pain management for the elderly

Researchers at The University of Texas at Arlington are focusing their attention on pain management in older adults, a segment of the population which presents a specific series of challenges to health providers.

20 Dec 2017

Clinical benefit of new cancer therapies may justify the expensive price

Researchers from the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, selected to estimate the cost-effectiveness of the newly approved CAR-T therapies, have found the clinical benefit may justify the expensive price.

20 Dec 2017

Antidepressant may also alleviate multiple sclerosis symptoms

The antidepressant clomipramine may also alleviate symptoms of multiple sclerosis (MS), specifically in its progressive form, i.e. when it occurs without relapses or remissions.

20 Dec 2017

Use of smoking cessation drug may put people at higher risk for cardiovascular events

Varenicline, one of the most commonly prescribed drugs for helping people quit smoking, may put them at higher risk for a cardiovascular event, according to new research published online in the American Journal of Respiratory and Critical Care Medicine.

20 Dec 2017

Study finds new way to explain hearing loss caused by cancer drug

Scientists have found a new way to explain the hearing loss caused by cisplatin, a powerful drug used to treat many forms of cancer. Using a highly sensitive technique to measure and map cisplatin in mouse and human inner ear tissues, researchers found that forms of cisplatin build up in the inner ear.

20 Dec 2017

FDA approves new gene therapy targeting rare form of inherited vision loss

The U.S. Food and Drug Administration today approved Luxturna (voretigene neparvovec-rzyl), a new gene therapy, to treat children and adult patients with an inherited form of vision loss that may result in blindness.

19 Dec 2017

Study finds combination therapy as effective strategy to treat ovarian cancers

Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations.

19 Dec 2017

UGR study paves way for development of better analgesics to treat joint pain

Researchers from the University of Granada have led a novel study in mice which shows that neurons mediating joint pain are different from those mediating cutaneous pain.

19 Dec 2017

FDA proposes new approach to the regulation of unapproved, potentially harmful homeopathic drugs

The U.S. Food and Drug Administration (FDA) is proposing a new, risk-based enforcement approach to the regulation of homeopathic products that are potentially the most harmful to people.

19 Dec 2017

Treatment for skin cancer could be more effective if combined with arthritis drug

Treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis, new research has shown.

19 Dec 2017

Drug industry spent millions to squelch talk about high drug prices

Facing bipartisan hostility over high drug prices in an election year, the pharma industry's biggest trade group boosted revenue by nearly a fourth last year and spread the millions collected among hundreds of lobbyists, politicians and patient groups, new filings show.

19 Dec 2017

Study suggests new treatment option for most lethal form of breast cancer

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine.

18 Dec 2017

Probiotics and xylitol chewing gum appear to have no effect in alleviating sore throat symptoms

The use of probiotics and xylitol chewing gum to alleviate sore throat symptoms -- as an alternative to antibiotics -- appears to have no effect, according to a randomized controlled trial (RCT) published in CMAJ.

18 Dec 2017

Diabetes patients least likely to follow medical advice regarding medication due to side effects

Diabetes patients who take the most commonly prescribed diabetes drug, metformin, are the least likely to follow medical advice regarding their medication due its side effects, a new article in the journal Diabetes, Obesity and Metabolism reports.

18 Dec 2017

Scientists use nanoparticles to fight Mucoviscidosis

Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination.

15 Dec 2017

Survey: Experts consider hazards of antibiotic resistances to be high

According to a survey among researchers, it is difficult to quantify the true extent of the hazards of antibiotic resistances to humankind.

15 Dec 2017

Kaiser Permanente delivers clot-busting drugs to stroke patients more than twice as fast as national rates

Kaiser Permanente hospitals in Northern California are delivering clot-busting medication to new stroke patients more than twice as fast as the national average. This follows the regionwide adoption of an integrated telemedicine program, according to new research published Dec. 15 in the journal Stroke.

15 Dec 2017

Rejected antibiotic candidate could be worth a second look, research finds

An antibiotic candidate compound shelved in the 1970s in favour of more worthwhile drugs could be worth a second look, new research has found.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017