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Short- and long-term ADHD medication users have lower risk of STIs, study finds

Attention-deficit/hyperactivity disorder (ADHD) increases the risk of subsequent sexually transmitted infections (STIs) among adolescent and young adult populations by about three times, reports a study published in the January 2018 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

3 Jan 2018

$Common drugs to prevent osteoporotic fractures lead to mineralization of bone cells$

Common drugs to prevent osteoporotic fractures lead to mineralization of bone cells

A study at Sahlgrenska Academy, Sweden, has found that one of the most common medications to prevent osteoporitic fractures gives rise to previously unknown mineralization of bone cells. The discovery may be important for understanding the effect of medication on bone quality.

2 Jan 2018

Experimental diabetes drugs can make cancer cells vulnerable to chemotherapy agents

Scientists at Dana-Farber Cancer Institute have shown that experimental diabetes drugs can make cancer cells more vulnerable to traditional chemotherapy agents, and they say such combinations should be explored to potentially improve outcomes for cancer patients.

2 Jan 2018

Suicidal ideations, attempts linked to opioid use and pain sensitivity in elderly

A new study published in the current issue of Psychotherapy and Psychosomatics suggests that suicidal ideations and suicide attempts are linked to opioid use and pain sensitivity in the elderly.

2 Jan 2018

Diabetes drug holds promise of being developed into new treatment for Alzheimer's

A drug developed for diabetes could be used to treat Alzheimer's after scientists found it "significantly reversed memory loss" in mice through a triple method of action.

2 Jan 2018

Researchers propose different approach to beat antibiotic-resistant superbugs

Got a sore throat? The doctor may write a quick prescription for penicillin or amoxicillin, and with the stroke of a pen help diminish public health and your own future health by helping bacteria evolve resistance to antibiotics.

30 Dec 2017

Proteasome inhibitor treatment can lead to cardiovascular problems in multiple myeloma patients

The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular problems in a higher than expected percentage of patients.

28 Dec 2017

Study: Higher dose of anti-seizure drug during pregnancy may increase baby's risk of cleft lip, palate

Taking a higher dose of topiramate during the first three months of pregnancy may increase a baby's risk of cleft lip or cleft palate more than when taking a lower dose, according to a study published in the December 27, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Dec 2017

Opioid prescribing for disabled Medicare beneficiaries related to county-level economic factors

For non-elderly Americans on disability, local prescribing of opioid pain medications is significantly related to county-level economic factors like unemployment and income level, reports a study in the January issue of Medical Care, published by Wolters Kluwer.

28 Dec 2017

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novartis announced today that the US Food and Drug Administration (FDA) approved the inclusion of Treatment-free Remission (TFR) data in the Tasigna® (nilotinib) US product label.

26 Dec 2017

T cell-inducing dengue vaccines could confer broader protection for kids born to vaccinated mothers

For a long time, a dengue vaccine was the holy grail in dengue research. Now that a dengue vaccine is finally on the market (Sanofi's Dengvaxia), other issues have arisen, such as what happens in the babies of vaccinated mothers.

22 Dec 2017

Study identifies biomarker targets to make existing drugs better at combating cancer

A new study published in Nature Communications and led by University of Kentucky Markey Cancer Center researcher Qing-Bai She identifies biomarker targets that may make existing drugs more effective in fighting certain cancers.

22 Dec 2017

FDA chief says he’s open to rethinking incentives on orphan drugs

The commissioner of the Food and Drug Administration questions whether the right financial incentives are in place for drugmakers who develop orphan drugs for rare diseases.

22 Dec 2017

Biosimilars, biologics and new legal challenges for RA treatments

Early last winter, Pfizer launched its new rheumatoid arthritis treatment, Inflectra, pricing it 15 percent below the $4,000-a-dose wholesale price of Remicade, the drug for which it is a close copy.

22 Dec 2017

FDA approves drug to increase blood pressure in adults with septic or distributive shock

The U.S. Food and Drug Administration today approved Giapreza (angiotensin II) injection for intravenous infusion to increase blood pressure in adults with septic or other distributive shock.

21 Dec 2017

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

The "mutational burden," or the number of mutations present in a tumor's DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimmel Cancer Center researchers shows.

21 Dec 2017

Tumor growth traits can influence response to cancer drugs, study finds

Individual tumors respond differently to cancer drugs, if at all. Until now, it remained a mystery why tumors have different reactions to the exact same therapy. But a new study at the USC Viterbi School of Engineering finds that tumor growth properties can influence response to cancer drugs.

21 Dec 2017

Drugs alone may not improve chances of successful quitting among smokers, study suggests

Pharmaceutical interventions are routinely prescribed to help people quit smoking. However, a new study by University of California San Diego School of Medicine researchers suggests that, despite promising results in clinical trials, smoking cessation drugs alone may not be improving the chances of successful quitting among smokers in general.

21 Dec 2017

FDA-approved drug to treat high blood pressure increases life span in worms

UT Southwestern Medical Center researchers find that an FDA-approved drug to treat high blood pressure seems to extend lifespan in worms via a cell signaling pathway that may mimic caloric restriction.

21 Dec 2017

New UGR study provides evidence for tramadol’s adverse effects on cycling performance

Tramadol is an opioid pain medication mainly used to treat moderate to severe pain, such as backache or postoperative pain. Although it has not yet been included in the list of banned substances by the World Anti-Doping Agency, the drug has recently generated significant media interest.

20 Dec 2017

Pharmaceutical News

Short- and long-term ADHD medication users have lower risk of STIs, study finds

Common drugs to prevent osteoporotic fractures lead to mineralization of bone cells

Experimental diabetes drugs can make cancer cells vulnerable to chemotherapy agents

Suicidal ideations, attempts linked to opioid use and pain sensitivity in elderly

Diabetes drug holds promise of being developed into new treatment for Alzheimer's

Researchers propose different approach to beat antibiotic-resistant superbugs

Proteasome inhibitor treatment can lead to cardiovascular problems in multiple myeloma patients

Study: Higher dose of anti-seizure drug during pregnancy may increase baby's risk of cleft lip, palate

Opioid prescribing for disabled Medicare beneficiaries related to county-level economic factors

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

T cell-inducing dengue vaccines could confer broader protection for kids born to vaccinated mothers

Study identifies biomarker targets to make existing drugs better at combating cancer

FDA chief says he’s open to rethinking incentives on orphan drugs

Biosimilars, biologics and new legal challenges for RA treatments

FDA approves drug to increase blood pressure in adults with septic or distributive shock

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

Tumor growth traits can influence response to cancer drugs, study finds

Drugs alone may not improve chances of successful quitting among smokers, study suggests

FDA-approved drug to treat high blood pressure increases life span in worms

New UGR study provides evidence for tramadol’s adverse effects on cycling performance

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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