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FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma cells. This sometimes-lethal intracranial tumor typically causes hearing loss and tinnitus

3 Apr 2018

BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Arthritis flares - the unpredictable and often sudden worsening of arthritis symptoms -- can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians.

3 Apr 2018

Many older adults support marijuana use with doctor’s recommendation, poll finds

Few older adults use medical marijuana, a new national poll finds, but the majority support its use if a doctor recommends it, and might talk to their own doctor about it if they developed a serious health condition.

3 Apr 2018

Genetic testing could help guide blood-thinner treatment after stent placement

Using genetic testing to inform which blood thinner to use following a procedure to open narrowed blood vessels resulted in significantly fewer complications among patients, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

3 Apr 2018

Acid-suppressing medicines and antibiotics in infancy linked to later allergic disease risk

The use of acid-suppressing medications or antibiotics in the first 6 months of infancy was associated with an increased risk for the subsequent development of allergic diseases in childhood.

2 Apr 2018

Study reveals how interneurons emerge and diversify in the brain

Modern neuroscience, for all its complexity, can trace its roots directly to a series of pen-and-paper sketches rendered by Nobel laureate Santiago Ramón y Cajal in the late 19th and early 20th centuries.

31 Mar 2018

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

The U.S. Food and Drug Administration granted accelerated approval to Blincyto (blinatumomab) to treat adults and children with B-cell precursor acute lymphoblastic leukemia (ALL) who are in remission but still have minimal residual disease (MRD).

30 Mar 2018

New review explores potentially safer therapies for treating chronic abdominal pain

An estimated 2 million people in the U.S. are addicted to prescription opioids- powerful doctor-prescribed medications for chronic or severe pain. The drugs are commonly prescribed to treat gastrointestinal pain caused by conditions such as Crohn's disease and irritable bowel syndrome (IBS), raising the risk of addiction among this population.

29 Mar 2018

Topical solution may be less cytotoxic than cryosurgery for patients with seborrheic keratosis

Seborrheic keratosis is the most common noncancerous skin growth in adults seen by doctors in everyday practice.

29 Mar 2018

Omissions on death certificates lead to undercounting of opioid overdoses

In a refrigerator in the coroner’s office in Marion County, Ind., rows of vials await testing. They contain blood, urine and vitreous, the fluid collected from inside a human eye.

29 Mar 2018

Enclosed point-of-use filter enhances quality of API for kidney dialysis

Amazon Filters reports a leading pharmaceutical company is using SupaPore PPG pleated depth filter cartridges to enable them to achieve a safe, enclosed point-of-use filter on their nitrogen gas distribution line used in the production of an Active Pharmaceutical Ingredient (API) for kidney dialysis treatments.

From Amazon Filters Ltd. 29 Mar 2018

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

Scientists at the National Institute on Drug Abuse Intramural Research Program have uncovered evidence that shows a more complex and elaborate role for the body's hard-working G protein-coupled receptors than previously thought, suggesting a conceptual advance in the fields of biochemistry and pharmacology.

28 Mar 2018

New long-acting delivery system has potential to lessen side effects from NRTIs

An HIV diagnosis, while no longer constituting a death sentence, brings with it a lifetime, daily regimen of medication to help continually combat the virus.

27 Mar 2018

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

27 Mar 2018

LSTM researchers show potential of novel antiparasitic drug to combat malaria

Researchers from the Liverpool School of Tropical Medicine have shown the large potential impact of a completely new type of antimalarial drug that kills mosquitoes, as opposed to existing drugs that target the parasite, to reduce the spread of malaria.

27 Mar 2018

Antibiotic use linked to higher risk of severe viral disease in mice

People infected with West Nile virus can show a wide range of disease. Some develop life-threatening brain infections. Others show no signs of infection at all. One reason for the different outcomes may lie in the community of microbes that populate their intestinal tracts.

27 Mar 2018

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo.

27 Mar 2018

Magnesium found to be effective for mild-to-moderate depression symptoms

Magnesium is effective for mild-to-moderate depression in adults, research has found.

From BetterYou Ltd 27 Mar 2018

MSU scientists test promising drug to prevent cancer in high-risk patients

Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

27 Mar 2018

New research does not support previous findings that antidepressants impact breastfeeding

New research does not support the previously observed negative impacts of antidepressant use on breastfeeding. In the British Journal of Clinical Pharmacology study, use of serotonin reuptake inhibitors in late pregnancy was not linked with an increased risk of women experiencing low milk supply.

26 Mar 2018

Pharmaceutical News

FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Many older adults support marijuana use with doctor’s recommendation, poll finds

Genetic testing could help guide blood-thinner treatment after stent placement

Acid-suppressing medicines and antibiotics in infancy linked to later allergic disease risk

Study reveals how interneurons emerge and diversify in the brain

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

New review explores potentially safer therapies for treating chronic abdominal pain

Topical solution may be less cytotoxic than cryosurgery for patients with seborrheic keratosis

Omissions on death certificates lead to undercounting of opioid overdoses

Enclosed point-of-use filter enhances quality of API for kidney dialysis

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

New long-acting delivery system has potential to lessen side effects from NRTIs

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

LSTM researchers show potential of novel antiparasitic drug to combat malaria

Antibiotic use linked to higher risk of severe viral disease in mice

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Magnesium found to be effective for mild-to-moderate depression symptoms

MSU scientists test promising drug to prevent cancer in high-risk patients

New research does not support previous findings that antidepressants impact breastfeeding

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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