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Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis.

4 Aug 2016

Researchers report promising vaccine strategy for immunizing against herpes viruses

Oral and genital herpes are caused by the herpes simplex virus type 1 (HSV-1) and the herpes simplex virus type 2 (HSV-2), which both cause lifelong infection. HSV-2 infection is associated with increased risk for HIV infection.

4 Aug 2016

Some WADA-banned substances may have potential medical applications

As the world awaits the start of the 2016 Summer Olympics, doping in athletes remains a hot topic.

4 Aug 2016

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases.

4 Aug 2016

Study finds high rate of misuse of seizure and pain drug

With increasing public attention to overdose deaths and misuse of prescription medications in the United States, researchers today presented the results of a new study looking at abuse and misuse of gabapentin, a medication used to treat seizures and relieve nerve pain often associated with shingles.

3 Aug 2016

New drug treatment could reduce body weight in obese patients with rare genetic disorder

As part of a phase II study at Charité - Universitätsmedizin Berlin and the Berlin Institute of Health, two obese patients with a rare genetic disorder were given a drug treatment to stimulate the satiety center in the brain.

3 Aug 2016

Neurologists identify cause of immune-mediated neuropathies

Würzburg neurologists have discovered an antibody that is involved in triggering certain forms of neuropathies. This discovery also allowed them to show a way to treat these diseases successfully.

3 Aug 2016

Research paves way for development of new drugs to prevent cancer and Alzheimer's

A new generation of drugs that prevent cancer and Alzheimer's could be developed, thanks to research from the University of Warwick.

3 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Reprogramming of the molecular pathways underlying normal metabolism is essential for T cell infection-fighting function and for the immune system to form a "memory" of the microbes it has already encountered. But exactly how metabolism in exhausted T cells is maintained in chronic infections and cancer is a missing element in this line of research.

3 Aug 2016

Research shows pharmacy access can help people from going back to hospital

Hospital readmissions, a $17 billion annual problem, are higher in rural, remote or smaller communities that sometimes have significantly less access to pharmacies, according to a study published today that was one of the first to examine this issue.

2 Aug 2016

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

In an attempt to correct defects in the energy generation that contribute to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure.

2 Aug 2016

Griffith University to collaborate with Olymvax for new vaccine technology that could benefit millions

Griffith University will partner with a Chinese pharmaceutical, Olymvax Biopharmaceuticals Inc. for a new vaccine that could benefit millions.

2 Aug 2016

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

A study led by St. Jude Children's Research Hospital found that obese mice are not protected against influenza infections by vaccines that include adjuvants, raising concerns about vaccine effectiveness in obese humans who are known to be at an increased risk for severe flu. The findings appear today in the scientific journal mBio.

2 Aug 2016

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Researchers at the Johns Hopkins Kimmel Cancer Center say they have developed a system that uses transformed human stem cells to speed up screening of existing drugs that might work against rare brain and other cancers.

2 Aug 2016

Generic biologic drugs appear to be as effective as brand-name versions

Generic forms of a biologic drug used to treat rheumatoid arthritis, inflammatory bowel disease and psoriasis appear to be as safe and effective as their brand-name counterparts, a new Johns Hopkins Bloomberg School of Public Health analysis suggests.

2 Aug 2016

Iron-containing catalysts can alter amino acids to help develop new drug candidates

For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids -- the building blocks of peptides and proteins -- into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness."

2 Aug 2016

Erectile dysfunction drugs do not play role in preventing prostate cancer, study shows

While some previous studies have indicated that taking erectile dysfunction (ED) drugs may reduce the likelihood of developing prostate cancer, new research published in The Journal of Urology found that these drugs do not play a role in preventing prostate cancer.

2 Aug 2016

New review examines potential of antioxidant therapies to combat neurodegenerative disorders

A new review examines the potential of antioxidant approaches for the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.

2 Aug 2016

Early initiation of antiretroviral therapy can considerably reduce total HIV DNA levels

A team of researchers, led by Drs. Merlin Robb and Jintanat Ananworanich of the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research, has found that when antiretroviral therapy (ART) is initiated during early acute HIV infection, it can significantly reduce total HIV DNA levels in the body, which may have implications for the goal of achieving long-term HIV remission.

2 Aug 2016

Pharmaceutical News

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Researchers report promising vaccine strategy for immunizing against herpes viruses

Some WADA-banned substances may have potential medical applications

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Study finds high rate of misuse of seizure and pain drug

New drug treatment could reduce body weight in obese patients with rare genetic disorder

Neurologists identify cause of immune-mediated neuropathies

Research paves way for development of new drugs to prevent cancer and Alzheimer's

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Research shows pharmacy access can help people from going back to hospital

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

Griffith University to collaborate with Olymvax for new vaccine technology that could benefit millions

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Generic biologic drugs appear to be as effective as brand-name versions

Iron-containing catalysts can alter amino acids to help develop new drug candidates

Erectile dysfunction drugs do not play role in preventing prostate cancer, study shows

New review examines potential of antioxidant therapies to combat neurodegenerative disorders

Early initiation of antiretroviral therapy can considerably reduce total HIV DNA levels

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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