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Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

A specially designed antidote to reverse acute, potentially life-threatening anticoagulant-related bleeding worked quickly, and was well-tolerated according to interim results of the ongoing ANNEXA-4 study.

30 Aug 2016

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Since the isolation of morphine from opium in the 19th century, scientists have hoped to find a potent opioid analgesic that isn't addictive and doesn't cause respiratory arrest with increased doses.

30 Aug 2016

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Nebivolol prevents anthracycline-induced cardiotoxicity, according to research presented at ESC Congress 2016 today by Professor Mirela Cleopatra Tomescu, a cardiologist at Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

30 Aug 2016

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

In microseconds, every light ray that enters the eye triggers an explosion of coordinated cellular events.

29 Aug 2016

Platelet function testing in elderly patients after heart attack shows no improved outcomes

Monitoring platelet function in order to individualize antiplatelet therapy did not improve outcomes for elderly patients after a heart attack compared to a standard, unmonitored approach, results of the ANTARCTIC trial show.

29 Aug 2016

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Patients who have heterozygous familial hypercholesterolemia (HeFH), a condition that causes abnormally raised low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease, can significantly reduce or even eliminate their need for expensive and time-consuming apheresis treatments with the PCSK9 inhibitor alirocumab.

29 Aug 2016

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Janssen-Cilag International NV has announced the submission of a Type II variation application to the European Medicines Agency (EMA), seeking to broaden the existing marketing authorisation for the immunotherapy DARZALEX® (daratumumab) to include treatment of adult patients with relapsed multiple myeloma who have received at least one prior therapy. The expanded indication is based on daratumumab in combination with lenalidomide (an immmunomodulatory agent) and dexamethasone, or bortezomib (a PI) and dexamethasone.

29 Aug 2016

New oral anticoagulants offer same stroke prevention, but cause less intracranial bleeding than warfarin

The new oral anticoagulants provide the same stroke prevention as warfarin but cause less intracranial bleeding, reports an observational study in more than 43 000 patients presented at ESC Congress 2016 today by Dr Laila Staerk, a research fellow at Herlev and Gentofte University Hospital, Denmark.

28 Aug 2016

ESC releases novel position paper on tackling cardiotoxicity of anticancer treatments

The European Society of Cardiology has launched a novel position paper, under the auspices of its Committee for Practice Guidelines, on tackling the cardiac toxicity of anticancer therapies. The cardio-oncology paper is published online today in European Heart Journal and on the ESC Website.

27 Aug 2016

DWC on target to implement workers' compensation drug formulary by July 2017

The Department of Industrial Relations' Division of Workers' Compensation (DIR/DWC) is on target to implement a workers' compensation drug formulary by July of next year as required by Assembly Bill 1124.

27 Aug 2016

Spotlight Innovation, FSU collaborate to support development of novel therapies for Zika virus infection

Spotlight Innovation Inc. has entered into a Sponsored Research Agreement with Florida State University to support research directed by FSU Prof. Hengli Tang aimed at developing safe and effective drugs to treat patients infected with Zika virus (ZIKV).

27 Aug 2016

Can-Fite BioPharma reports financial results, provides update on drug development programs

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today reported financial results for the six months ended June 30, 2016 and updates on its drug development programs.

27 Aug 2016

Hitchhiking of drugs on incorrect targets can cause adverse side effects

It probably isn't surprising to read that pharmaceutical drugs don't always do what they're supposed to. Adverse side effects are a well-known phenomenon and something many of us will have experienced when taking medicines.

26 Aug 2016

New drug delivery system slows and controls tumors not aiming for complete elimination

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.

26 Aug 2016

Pharmaceutical News

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

Platelet function testing in elderly patients after heart attack shows no improved outcomes

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

New oral anticoagulants offer same stroke prevention, but cause less intracranial bleeding than warfarin

ESC releases novel position paper on tackling cardiotoxicity of anticancer treatments

DWC on target to implement workers' compensation drug formulary by July 2017

Spotlight Innovation, FSU collaborate to support development of novel therapies for Zika virus infection

Can-Fite BioPharma reports financial results, provides update on drug development programs

Hitchhiking of drugs on incorrect targets can cause adverse side effects

New drug delivery system slows and controls tumors not aiming for complete elimination

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

NPS MedicineWise spokesperson reveals how to look for information about medicines online

CPhI Pre-Connect Congress to provide insights on major developments in pharmaceutical industry

Researchers show how cannabinoids affect vision

New synthetic methods facilitate development of bioactive and chemical compounds

Study reports significant under-use of topical INS therapy for chronic rhinosinusitis patients

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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