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UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

Though the drug levodopa can dramatically improve Parkinson's disease symptoms, within five years one-half of the patients using L-DOPA develop an irreversible condition -- involuntary repetitive, rapid and jerky movements.

29 Jul 2016

New study to examine genomics of anti-platelet therapy after coronary interventions

Which antiplatelet medication is best after a coronary stent? The Tailored Antiplatelet Therapy to Lessen Outcomes After Percutaneous Coronary Intervention (TAILOR-PCI) Study examines whether prescribing heart medication based on a patient's CYP2C19 genotype will help prevent heart attack, stroke, unstable angina, and cardiovascular death in patients who undergo percutaneous coronary intervention (PCI), commonly called angioplasty.

29 Jul 2016

Discovery of pain paradox paves way to new methods of pain control

A natural substance known to activate pain in the central nervous system has been found to have the opposite effect in other parts of the body, potentially paving the way to new methods of pain control.

28 Jul 2016

Updated AAN guidelines state closure not recommended for individuals with stroke and heart defect

An updated recommendation from the American Academy of Neurology states that catheter-based closure should not be routinely recommended for people who have had a stroke and also have a heart defect called a patent foramen ovale (PFO), a channel between the top two chambers in the heart.

28 Jul 2016

FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

The U.S. Food and Drug Administration approved Adlyxin (lixisenatide), a once-daily injection to improve glycemic control (blood sugar levels), along with diet and exercise, in adults with type 2 diabetes.

28 Jul 2016

Resveratrol may be clinically beneficial to people with Alzheimer's disease

Resveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain barrier, reducing the ability of harmful immune molecules secreted by immune cells to infiltrate from the body into brain tissues, say researchers at Georgetown University Medical Center.

28 Jul 2016

Researchers discover two plant-derived compounds with potential for fighting inflammation and pain

New research reveals that two specific plant-derived compounds may be effective for fighting inflammation and pain. The findings are published in the British Journal of Pharmacology.

28 Jul 2016

Researchers find promising new therapy for both pediatric and adult cancers

A study conducted at Nationwide Children's Hospital has found that a new chemotherapy is effective against both pediatric and adult cancers, and that it allows other chemotherapies to more readily reach their targets.

28 Jul 2016

UNMC researcher aims to find workable solution for tackling antibiotic resistance

Sam Sanderson, Ph.D., a research associate professor in the UNMC College of Pharmacy, recently secured an R01 grant from the National Institutes of Health to find a workable solution to the problem of antibiotic resistance.

28 Jul 2016

TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

In addition to its more obvious ills, type 2 diabetes is a condition closely associated with bone fractures, increasing the risk of fractures twofold. To make matters worse, certain anti-diabetic drugs further increase this risk, particularly in postmenopausal women, severely limiting their treatment options.

28 Jul 2016

Children taking ADHD medication less likely to suffer consequences of risky behaviors

New research provides some of the first evidence that medications taken by millions of American children to treat attention-deficit/hyperactivity disorder (ADHD) offer long-term benefits.

27 Jul 2016

Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

A drink developed for soldiers to generate energy from ketones rather than carbs or fat allowed highly trained cyclists to add up to 400 meters of distance to their workouts, a UK-led study reports July 27 in Cell Metabolism.

27 Jul 2016

Study evaluates effectiveness of psychotherapy in SAD patients who fail to respond to antidepressants

A randomized controlled study has evaluated the role of psychotherapy in patients whose social anxiety did not respond to drug treatment.

27 Jul 2016

New non-drug approach may help manage pain in individuals receiving addiction treatment

It's a Catch-22 with potentially deadly consequences: People trying to overcome addiction can't get treatment for their pain, because the most powerful pain medicines also carry an addiction risk.

27 Jul 2016

New combination treatment improves overall survival in patients with malignant melanoma

Among patients with melanoma, those who received both ipilimumab (Yervoy) and local peripheral treatments such as radiotherapy or electrochemotherapy had significantly prolonged overall survival compared with those who received only ipilimumab, according to a retrospective clinical study.

27 Jul 2016

FDA approves safety labeling changes for fluoroquinolone antibiotics

The U.S. Food and Drug Administration today approved safety labeling changes for a class of antibiotics, called fluoroquinolones, to enhance warnings about their association with disabling and potentially permanent side effects and to limit their use in patients with less serious bacterial infections.

27 Jul 2016

Penn researchers use iron-containing nanoparticles to reduce plaque and prevent tooth decay

The bacteria that live in dental plaque and contribute to tooth decay often resist traditional antimicrobial treatment, as they can "hide" within a sticky biofilm matrix, a glue-like polymer scaffold.

26 Jul 2016

Study shows drugs for hypertension may help treat mood disorders

In the current issue of Psychotherapy and Psychosomatics, the relationship of drugs that are generally used for treating hypertension (angiotensin converting enzyme inhibitors) are examined in their effects as to depression.

26 Jul 2016

Novel community-produced biological network models hold potential in drug discovery and toxicology

A new set of community-produced biological network models has been shown to allow a deeper understanding of the mechanisms underlying a range of diseases.

26 Jul 2016

Study identifies key risk factors involved in patient-to-patient transmission of drug-resistant bacteria

Three key factors increase the risk for patient-to-patient transmission of an extremely drug-resistant bacteria known as CP-CRE, according to a new study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

26 Jul 2016

Pharmaceutical News

UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

New study to examine genomics of anti-platelet therapy after coronary interventions

Discovery of pain paradox paves way to new methods of pain control

Updated AAN guidelines state closure not recommended for individuals with stroke and heart defect

FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

Resveratrol may be clinically beneficial to people with Alzheimer's disease

Researchers discover two plant-derived compounds with potential for fighting inflammation and pain

Researchers find promising new therapy for both pediatric and adult cancers

UNMC researcher aims to find workable solution for tackling antibiotic resistance

TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

Children taking ADHD medication less likely to suffer consequences of risky behaviors

Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

Study evaluates effectiveness of psychotherapy in SAD patients who fail to respond to antidepressants

New non-drug approach may help manage pain in individuals receiving addiction treatment

New combination treatment improves overall survival in patients with malignant melanoma

FDA approves safety labeling changes for fluoroquinolone antibiotics

Penn researchers use iron-containing nanoparticles to reduce plaque and prevent tooth decay

Study shows drugs for hypertension may help treat mood disorders

Novel community-produced biological network models hold potential in drug discovery and toxicology

Study identifies key risk factors involved in patient-to-patient transmission of drug-resistant bacteria

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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