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Novel method can test multi-drug resistant bacteria’s susceptibility to antibiotics in clinical setting

The recent emergence of bacterial infections that are resistant to many existing antibiotics is driving an urgent need for tools to quickly identify the small number of therapies that are still effective for individual patients.

15 Jul 2016

IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Hospital-acquired pneumonia and ventilator-associated pneumonia– which account for 20 to 25 percent of hospital-acquired infections – should be treated with shorter courses of antibiotics than they typically are, according to new guidelines released by the Infectious Diseases Society of America and American Thoracic Society and published in the journal Clinical Infectious Diseases.

14 Jul 2016

Researchers identify new drug target for treating children with CNS-PNET

Primitive neuroectodermal tumors (PNETs) are the largest group of malignant brain tumors in children. They can arise from the brain's cerebellum or, more rarely, from tissue located throughout the central nervous system (CNS).

14 Jul 2016

Study finds low rates of baseline BMD testing among older women with breast cancer

Aromatase inhibitors (AIs)—drugs that stop the production of estrogen in women—are standard adjuvant therapy for post-menopausal women with hormone-receptor positive breast cancer.

14 Jul 2016

Combination approach could be more effective to treat fibromyalgia pain

Queen's University researcher Ian Gilron has uncovered a more effective way of treating fibromyalgia, a medical condition characterized by chronic widespread pain typically accompanied by fatigue, as well as sleep, mood and memory problems.

14 Jul 2016

Penn study provides more insights into cardiovascular side effects of breast cancer drug

A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

14 Jul 2016

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

Older adults with chronic obstructive pulmonary disease who start using opioids have a more than two-fold higher risk of dying from a respiratory-related complication compared to non-opioid users, St. Michael's Hospital researchers have found.

14 Jul 2016

New treatment approach may benefit relapsed post-transplant blood cancer patients

For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognosis.

13 Jul 2016

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

UCLA researchers have for the first time identified mechanisms that determine how advanced melanoma can become resistant to immune checkpoint inhibitors, a discovery that could lead to the development of new and improved treatments for the deadliest type of skin cancer.

13 Jul 2016

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

A Houston Methodist research team received a nearly $4 million grant to test a transcutaneously refillable implant that administers pre-exposure prophylaxis drugs to subjects at risk of HIV-exposure.

13 Jul 2016

Policies restricting opioid prescriptions could harm pain patients, suggests review

A recent review and analysis suggests that some policies restricting opioid prescriptions to curb overdose deaths could be harming those who need them the most: pain patients.

13 Jul 2016

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.

12 Jul 2016

Scientists reveal how manipulating novel target in the brain could lead to new therapies for depression

Northwestern Medicine scientists have shown how manipulating a novel target in the brain using gene therapy could lead to new treatments for depression.

12 Jul 2016

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

With more than 7.5 million new cases of Alzheimer’s disease a year, the race to find a vaccine and effective treatment for dementia is growing by the day.

12 Jul 2016

CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

Non-alcoholic steatohepatitis (NASH) is a serious hepatic condition that precedes hepatocellular carcinoma (HCC) and is currently untreatable.

12 Jul 2016

Penn researchers use drug-pricing model to estimate average joint weight of marijuana

How much marijuana does the average joint contain? "It seems like an odd question but major policy questions depend on the answer," said Greg Ridgeway, an associate professor of criminology and statistics at the University of Pennsylvania.

12 Jul 2016

Shire’s Xiidra receives FDA approval for treating dry eye disease in adult patients

Shire plc announces that the U.S. Food and Drug Administration has approved Xiidra (lifitegrast ophthalmic solution) 5%, a twice-daily eye drop solution indicated for the treatment of the signs and symptoms of dry eye disease in adult patients.

12 Jul 2016

Urolithin A found in pomegranates may improve muscle strength and endurance during aging

Amazentis SA, an innovative life sciences company applying scientific breakthroughs in nutrition to manage health conditions linked to aging, announced today a collaborative publication in Nature Medicine with the École Polytechnique Fédérale de Lausanne, demonstrating that the Company's lead product candidate, urolithin A, improves mitochondrial and muscle function, resulting in enhanced muscle strength and endurance during aging.

11 Jul 2016

Researchers receive $9 million grant to develop novel platform to quickly identify new antibiotics

In September 2014, President Obama issued an executive order for "Combating Antibiotic- Resistant Bacteria." Why the urgency? The Centers for Disease Control and Prevention, the order noted, "estimates that annually at least 2 million illnesses and 23,000 deaths are caused by antibiotic- resistant bacteria in the United States alone."

11 Jul 2016

UVA receives grant to combat opioid epidemic in Southwest Virginia

A federal grant to the University of Virginia Health System will help battle the opioid epidemic in Southwest Virginia by expanding access to specialized care through telehealth.

11 Jul 2016

Pharmaceutical News

Novel method can test multi-drug resistant bacteria’s susceptibility to antibiotics in clinical setting

IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Researchers identify new drug target for treating children with CNS-PNET

Study finds low rates of baseline BMD testing among older women with breast cancer

Combination approach could be more effective to treat fibromyalgia pain

Penn study provides more insights into cardiovascular side effects of breast cancer drug

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

New treatment approach may benefit relapsed post-transplant blood cancer patients

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

Policies restricting opioid prescriptions could harm pain patients, suggests review

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Scientists reveal how manipulating novel target in the brain could lead to new therapies for depression

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

Penn researchers use drug-pricing model to estimate average joint weight of marijuana

Shire’s Xiidra receives FDA approval for treating dry eye disease in adult patients

Urolithin A found in pomegranates may improve muscle strength and endurance during aging

Researchers receive $9 million grant to develop novel platform to quickly identify new antibiotics

UVA receives grant to combat opioid epidemic in Southwest Virginia

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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