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Combination of two plant compounds holds promise in treating colon cancer

The combination of two plant compounds that have medicinal properties - curcumin and silymarin - holds promise in treating colon cancer, according Saint Louis University research published in the June 23 issue of the Journal of Cancer.

22 Jul 2016

Study uncovers new drug-gene mutation combinations that can kill cancer cells

In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells.

22 Jul 2016

New on-line resource allows user to virtually test effectiveness, specificity of potential drug

Inside the human body, the same drug can interact with multiple molecules. This phenomenon is known as 'polypharmacology' and, according to the interaction, a drug can cure a disease or cause side effects in the patient.

22 Jul 2016

Combinations of three antibiotics could help combat drug-resistant bacterial infections

Each year, approximately 700,000 people die from drug-resistant bacterial infections. A study by UCLA life scientists could be a major step toward combating drug-resistant infections.

22 Jul 2016

Scientist develops new method for identifying proteins to build new biologics

A University of Toronto scientist has developed a new method for identifying the raw ingredients necessary to build 'biologics', a powerful class of medications that has revolutionized treatment of diseases like rheumatoid arthritis and some cancers.

22 Jul 2016

New neuroprotective compounds may prevent development of epilepsy

A team led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of LSU Health New Orleans' Neuroscience Center of Excellence, has developed neuroprotective compounds that may prevent the development of epilepsy.

22 Jul 2016

Scientists design and construct 10 large protein icosahedra to improve drug delivery

Using novel computational and biochemical approaches, scientists have accurately designed and built from scratch 10 large protein icosahedra--polyhedra with 20 faces--similar to viral capsids that carry viral DNA.

22 Jul 2016

Adults with pain could be at higher risk of developing prescription opioid use disorders

What do we really know about the relationship between the experience of pain and risk of developing opioid use disorder? Results from a recent study - the first to directly address this question -- show that people with moderate or more severe pain had a 41 percent higher risk of developing prescription opioid use disorders than those without, independent of other demographic and clinical factors.

22 Jul 2016

Texas Biomed scientists receive $23 million NIH grant to develop AIDS vaccine

To support a coordinated, innovative approach to the development of an AIDS vaccine, Texas Biomedical Research Institute scientists, together with a multi-institutional coalition of experts from the United States and Europe, have received a grant for $23 million from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health.

22 Jul 2016

Patients with cLBP more likely to use illicit drugs, study reports

People living with chronic low back pain (cLBP) are more likely to use illicit drugs -- including marijuana, cocaine, heroin, and methamphetamine -- compared to those without back pain, reports a study in Spine, published by Wolters Kluwer.

21 Jul 2016

BET inhibitor treatment decreases lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage.

21 Jul 2016

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Neutron crystallography allows us to determine the three-dimensional structures of biological macromolecules, such as proteins, by means of the diffraction of neutrons from the regularly spaced atoms of a crystal.

21 Jul 2016

Improving efficiency of health facilities could extend ART to many people living with HIV

Health facilities in Kenya, Uganda, and Zambia could extend life-sustaining antiretroviral therapy (ART) to hundreds of thousands of people living with HIV if facilities improved the efficiency of service delivery.

21 Jul 2016

Study provides new insights into real-world use of PrEP

Several studies presented today in an official press conference at the 21st International AIDS Conference in Durban provided new insights on the use of PrEP among a broad range of populations.

21 Jul 2016

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

A collaboration between the University of Leicester and global pharmaceutical company GlaxoSmithKline has been established to discover and develop novel medicines to treat aggressive forms of blood cancer.

21 Jul 2016

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Long-term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a new study by neuroscientists from the University of Chicago.

21 Jul 2016

Pharmaceutical News

Combination of two plant compounds holds promise in treating colon cancer

Study uncovers new drug-gene mutation combinations that can kill cancer cells

New on-line resource allows user to virtually test effectiveness, specificity of potential drug

Combinations of three antibiotics could help combat drug-resistant bacterial infections

Scientist develops new method for identifying proteins to build new biologics

New neuroprotective compounds may prevent development of epilepsy

Scientists design and construct 10 large protein icosahedra to improve drug delivery

Adults with pain could be at higher risk of developing prescription opioid use disorders

Texas Biomed scientists receive $23 million NIH grant to develop AIDS vaccine

Patients with cLBP more likely to use illicit drugs, study reports

BET inhibitor treatment decreases lung inflammation in mice

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Improving efficiency of health facilities could extend ART to many people living with HIV

Study provides new insights into real-world use of PrEP

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Scientific review cautions against unnecessary use of antioxidant supplements

TSRI study reveals new approach to intervene in deadly disease

Penn researchers develop plant-based oral vaccine booster

Study confirms efficacy of PrEP in reducing risk of HIV infection in men who have sex with men

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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