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Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Mapping the molecular structure where medicine goes to work is a crucial step toward drug discovery against deadly diseases.

21 Jun 2016

Study shows Alzheimer's disease can lead to diabetes

Drugs used to treat diabetes could also be used to treat Alzheimer's disease, and vice versa, according to new research from the University of Aberdeen.

21 Jun 2016

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

A new meta-analysis published in Clinical Nutrition found that cardiac surgery patients who received omega-3 polyunsaturated fatty acids (compared to placebo) in advance of surgery experienced reduced postoperative cardiac arrhythmias and significantly reduced the length of hospital stay by up to 2.4 days. The results are based on 11 RCT's with 1038 patients.

21 Jun 2016

Unmanned drones could be economical to deliver vaccines quickly in developing countries

Using unmanned drones to deliver vaccines in low- and middle-income countries may save money and improve vaccination rates, new research led by the Johns Hopkins Bloomberg School of Public Health and the Pittsburgh Supercomputing Center suggests.

21 Jun 2016

New Aspirin-Guide mobile app helps clinicians and patients make informed decisions about aspirin use

Low dose aspirin is recommended by clinicians as a preventive measure for patients who have already had a heart attack or stroke, but the risk of taking low-dose aspirin to prevent or delay a first heart attack or stroke is less clear, as the benefit for reducing the risk of cardiovascular disease (CVD) must be balanced with the increased risk of gastrointestinal or other bleeding.

21 Jun 2016

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Mayo Clinic is highlighting the potential merits of using precision medicine in prescribing antidepressants. Details appear in the current issue of Mayo Clinic Proceedings.

21 Jun 2016

Potential therapeutic approaches to combat chronic myeloid leukemia

Chronic myeloid leukemia (CML) develops through chromosomal alterations in blood-forming cells of the bone marrow and usually occurs in older persons. Around 20 percent of adults diagnosed with leukemia suffer from this type of blood cancer.

21 Jun 2016

Researchers aim to improve medical treatment for people with insect venom allergy

A team of researchers has elucidated individual profiles of allergy reactivity in patients that are not protected after treatment with immunotherapy. The aim is to improve medical treatment of people who are allergic to insect stings.

21 Jun 2016

Fixed-dose combination of sacubitril and valsartan for heart failure shows differing added benefit

The fixed-dose combination of sacubitril and valsartan (trade name: Entresto) has been approved since November 2015 for adults with symptomatic chronic heart failure with reduced pump function.

21 Jun 2016

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

In a small study looking at pain assessments in adults with sickle cell disease, researchers at Johns Hopkins says overall, those treated long-term with opioids often fared worse in measures of pain, fatigue and curtailed daily activities than those not on long-term opioids.

21 Jun 2016

AF patients at risk for stroke mostly treated with aspirin-only prescription instead of blood thinners

Researchers at University of California San Diego School of Medicine and University of California, San Francisco School of Medicine report that more than 1 in 3 atrial fibrillation (AF) patients at intermediate to high risk for stroke are treated with aspirin alone, despite previous data showing this therapy to be inferior to blood thinners.

21 Jun 2016

Fractional dosing approach could be used to control yellow fever outbreaks during vaccine shortages

The yellow fever vaccine given as one fifth of the regular dose could be used to control an outbreak in case of vaccine shortages.

20 Jun 2016

TUM researchers uncover molecular mechanism of thalidomide

In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have remained unclear.

20 Jun 2016

Watchman device for irregular heart rhythms may be preferable to standard blood thinning medications

A new study by a Yale researcher may support the use of a device for patients suffering from irregular heart rhythms.

17 Jun 2016

Statins can lower infection risk by 58% in stroke patients

A Washington State University researcher has found that statin drugs can dramatically lower the risk of infections in stroke patients.

17 Jun 2016

NPS MedicineWise urges Australians to stop expecting antibiotics for colds and flu

With new findings launched today showing that antimicrobial use in the community in Australia is higher than in England, Canada, Norway, Denmark, Sweden and the Netherlands—and that the number of antimicrobials being prescribed in Australia continues to grow—NPS MedicineWise is again urging Australians to stop expecting antibiotics for viruses such as colds and flu.

17 Jun 2016

S1P1R variation may cause differential patient responses to fingolimod treatment

Multiple sclerosis (MS) is an autoimmune disorder that results in demyelination of neurons. The FDA-approved drug fingolimod (Gilenya, FTY-720) modulates signaling by the bioactive lipid sphingosine-1-phosphate (S1P), which is linked to MS pathogenesis.

16 Jun 2016

New research paves way for potential notch-based anticancer therapeutics

A recent study led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, in collaboration with the Univerity of Maryland School of Pharmacy and StemSynergy Therapeutics, Inc., has identified a small-molecule inhibitor of the Notch pathway, paving the way for a potential new class of personalized cancer medicines.

16 Jun 2016

TSRI scientists develop novel technique for finding drug candidates

Scientists at The Scripps Research Institute have developed a powerful new method for finding drug candidates that bind to specific proteins.

16 Jun 2016

New analytical technology could improve cancer treatment by establishing ideal dosing regimens

University of Oklahoma researchers will apply a new analytical technology that could ultimately provide a powerful tool for improved treatment of cancer patients in Oklahoma and beyond. Using mass spectrometry, an analytical instrument for sensitive detection and accurate

15 Jun 2016

Pharmaceutical News

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Study shows Alzheimer's disease can lead to diabetes

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

Unmanned drones could be economical to deliver vaccines quickly in developing countries

New Aspirin-Guide mobile app helps clinicians and patients make informed decisions about aspirin use

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Potential therapeutic approaches to combat chronic myeloid leukemia

Researchers aim to improve medical treatment for people with insect venom allergy

Fixed-dose combination of sacubitril and valsartan for heart failure shows differing added benefit

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

AF patients at risk for stroke mostly treated with aspirin-only prescription instead of blood thinners

Fractional dosing approach could be used to control yellow fever outbreaks during vaccine shortages

TUM researchers uncover molecular mechanism of thalidomide

Watchman device for irregular heart rhythms may be preferable to standard blood thinning medications

Statins can lower infection risk by 58% in stroke patients

NPS MedicineWise urges Australians to stop expecting antibiotics for colds and flu

S1P1R variation may cause differential patient responses to fingolimod treatment

New research paves way for potential notch-based anticancer therapeutics

TSRI scientists develop novel technique for finding drug candidates

New analytical technology could improve cancer treatment by establishing ideal dosing regimens

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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