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Researchers identify promising new compound for targeting triple-negative breast cancer

Researchers at the University of Michigan have identified a promising new compound for targeting one of the most aggressive types of breast cancer.

9 Jun 2016

Mathematical approach can help achieve optimal dosing for various drugs

In treating diseases with drugs, dosing is critical; too little is ineffective, while too much can be lethal. Colorado State University's Brad Reisfeld takes a mathematical approach to achieving optimal dosing for various drugs.

9 Jun 2016

U-M study compares early-use and longer-duration stimulant medication with nonstimulant therapy for ADHD

Youth who take Ritalin, Adderall or other stimulant medications for ADHD over an extended period of time early in life are no more at risk for substance abuse in later adolescence than teens without ADHD, according to a University of Michigan study.

9 Jun 2016

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

The metabolite of a drug that is helping patients battle multiple sclerosis appears to significantly slow the onset of Parkinson's disease, researchers say.

9 Jun 2016

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

Life Extension (use different web link to highlight our technical attributes), a Florida-based organization established in the early 1980s is dedicated to extending healthy human longevity.

8 Jun 2016

New drug-capture device can soak up chemotherapy drugs to limit toxicity

Doctors have a powerful arsenal of cancer-fighting chemotherapy drugs to choose from, though a key challenge is to better target these drugs to kill tumors while limiting their potentially harmful side effects.

8 Jun 2016

Children in foster care still face quality challenges in antipsychotic medication use

Significant quality challenges persist in antipsychotic medication use for children in foster care and other Medicaid-insured children, according to a new Rutgers University-New Brunswick study published in Health Affairs.

8 Jun 2016

New immunization approach may one day wipe out pneumonia, meningitis

A new vaccine allows pneumonia-causing bacteria to colonize inside the body, springing into action only if the bacteria pose a threat.

8 Jun 2016

Maternal topiramate use in conjunction with other anti-epileptic drugs may cause fetal malformations

In an analysis of pregnancies in Australia from 1999 to 2014 in which women were taking anti-epileptic drugs, fetal malformation rates fell over time in pregnancies where only one drug was taken, but rates increased in pregnancies where multiple drugs were taken.

8 Jun 2016

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

A drug, more commonly used in the treatment of angina, could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis

8 Jun 2016

Coagadex now available for rare bleeding disorder patients in the UK

Bio Products Laboratory, Limited (BPL) today announced that Coagadex is now available for patients in the UK.

7 Jun 2016

Existing immunotherapy drug pembrolizumab shows promise for specific sarcoma subtypes

An existing cancer immunotherapy drug reduces tumor size in some types of rare connective tissue cancers, called sarcomas, report researchers at the University of Pittsburgh Cancer Institute.

7 Jun 2016

Multi-center study may help reassure breast cancer patients taking tamoxifen drug

A study led by Loyola Medicine researchers may help reassure patients who worry the breast cancer drug tamoxifen could increase their risk of uterine cancer.

7 Jun 2016

New systems-based strategy may help accelerate TB drug discovery

The rise in multi-drug resistant (MDR) and extremely drug resistant (XDR) strains of Mycobacterium tuberculosis (MTB) is becoming a major cause of global health concern for treating tuberculosis, which affects a third of the global population.

7 Jun 2016

Myricitrin may play role in preventing neuronal degeneration in Parkinson's disease

A new study has shown that myricitrin, a flavinoid with antioxidant and anti-inflammatory activity that is present inedible plants and fruit, can protect mouse brains from the loss of dopamine-producing neurons caused by neurotoxicity.

7 Jun 2016

Eculizumab drug provides new hope for kidney failure patients

Surgeons at the University of Illinois Hospital & Health Sciences System have — for the first time — used an orphan drug to prevent rejection of a kidney transplanted from a living donor with a mismatched blood type.

7 Jun 2016

Taking hormone therapy drugs for additional five years improves outcomes in breast cancer patients

Breast cancer patients significantly benefit by taking hormone therapy drugs called aromatase inhibitors for an additional five years, according to a major study presented at the Plenary Session of the American Society of Clinical Oncology annual meeting in Chicago and published in the New England Journal of Medicine.

7 Jun 2016

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn't just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients.

7 Jun 2016

$One-third of osteoporotic women taking oral bisphosphonates have elevated risk for bone fracture$

One-third of osteoporotic women taking oral bisphosphonates have elevated risk for bone fracture

More than 53 million Americans age 50 and older, primarily women, have osteoporosis or are at high risk for the condition due to low bone density. A recent study of oral bisphosphonates, the most commonly prescribed osteoporosis treatment, found that approximately a third of women prescribed these drugs continue to be at elevated risk for bone fracture, an outcome that may have several origins.

7 Jun 2016

Higher blood levels of methotrexate impair executive functioning in long-term pediatric ALL survivors

Research from St. Jude Children's Research Hospital suggests that pediatric leukemia patients exposed to higher concentrations of the chemotherapy drug methotrexate are more likely to struggle with mental flexibility, organization and related skills as long-term survivors.

7 Jun 2016

Pharmaceutical News

Researchers identify promising new compound for targeting triple-negative breast cancer

Mathematical approach can help achieve optimal dosing for various drugs

U-M study compares early-use and longer-duration stimulant medication with nonstimulant therapy for ADHD

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

Life Extension, Insilico Medicine team up to identify novel biomarkers of human aging

New drug-capture device can soak up chemotherapy drugs to limit toxicity

Children in foster care still face quality challenges in antipsychotic medication use

New immunization approach may one day wipe out pneumonia, meningitis

Maternal topiramate use in conjunction with other anti-epileptic drugs may cause fetal malformations

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

Coagadex now available for rare bleeding disorder patients in the UK

Existing immunotherapy drug pembrolizumab shows promise for specific sarcoma subtypes

Multi-center study may help reassure breast cancer patients taking tamoxifen drug

New systems-based strategy may help accelerate TB drug discovery

Myricitrin may play role in preventing neuronal degeneration in Parkinson's disease

Eculizumab drug provides new hope for kidney failure patients

Taking hormone therapy drugs for additional five years improves outcomes in breast cancer patients

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

One-third of osteoporotic women taking oral bisphosphonates have elevated risk for bone fracture

Higher blood levels of methotrexate impair executive functioning in long-term pediatric ALL survivors

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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