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Experimental lipid-lowering drug improves glucose control in diabetic patients

High triglycerides -- a type of fat, or lipid, in the blood -- increase the risk of heart disease and perhaps type 2 diabetes. For the first time, it has been shown that profoundly lowering triglycerides in diabetics improves their insulin sensitivity over time, which helps them maintain healthy glucose - blood sugar -- levels.

28 Jun 2016

Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Researchers at Johns Hopkins say they have gleaned two important new clues in the fight against Parkinson's disease: that blocking an enzyme called c-Abl prevents the disease in specially bred mice, and that a chemical tag on a second protein may signal the disorder's presence and progression.

28 Jun 2016

Researchers test new drug with potential to reverse or slow progression of asthma

A new drug with the potential to reverse or slow the development of asthma is being tested by researchers at The University of Queensland.

28 Jun 2016

Pain reliever appears to help preserve vision in animal model of retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in a model of severe retinal degeneration, scientists report.

28 Jun 2016

Cisplatin-based chemotherapy may lead to hearing loss in many testicular cancer survivors

Many testicular cancer survivors experience hearing loss after cisplatin-based chemotherapy, according to researchers at Indiana University.

28 Jun 2016

Anti-anxiety medication dampens helping behavior in rats

Rats given midazolam, an anti-anxiety medication, were less likely to free trapped companions because the drug lessened their empathy, according to a new study by University of Chicago neuroscientists.

28 Jun 2016

Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

Vaccination with the anthrax capsule--a naturally occurring component of the bacterium that causes the disease--completely protected monkeys from lethal anthrax infection, according to a study published online this week in the journal VACCINE.

27 Jun 2016

HDAC inhibitors may help regulate alcoholism-induced anxiety

Epigenetics is the study of changes in organisms caused by modifying gene expression - by alcohol, for example - rather than alteration of the genetic code itself. Recent evidence suggests that alcohol can inhibit activity of an enzyme called histone deacetylase (HDAC) in the amygdala, a brain region that is crucial for storing memories and regulating fear, anxiety, and other emotions.

27 Jun 2016

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

The European Society of Clinical Microbiology and Infectious Diseases and the American Society for Microbiology (ASM) are jointly organizing a conference in Vienna from 21 – 23 September 2016 to help researchers accelerate the development of new antimicrobials for drug-resistant infections.

27 Jun 2016

Federal government continues to ban valid scientific research on medicinal use of Cannabis sativa

The use of medical marijuana for millions of patients suffering from a wide range of health conditions and the subsequent therapeutic benefits has long been documented.

25 Jun 2016

Oncogene signatures could help design new drug treatments for breast cancer

Drug treatments for breast cancer patients might soon be designed based on the unique genetic autograph of their tumor.

25 Jun 2016

Novel combination therapy may help provide clinically successful treatment for AD

Resveratrol is a naturally occurring polyphenolic phytochemical produced in several plants, especially grapes skin and seeds. One epidemiological study reported a positive association between moderate red wine consumption and a low incidence of cardiovascular disease, known as the "French Paradox."

25 Jun 2016

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

One of the first clues pathologists look for in tissue from a newly diagnosed breast cancer patient is the estrogen receptor, a nuclear protein that converts hormonal messages in the bloodstream into instructions for the cell about how to behave

24 Jun 2016

New book highlights advances, challenges in development of nanotheranostics for personalized medicine

The future of medicine is now dawning upon us.Nanomedicines demonstrate the capability to enhance drug properties by offering protection from degradation, enabling controlled release and biodistribution and increasing bioavailability.

24 Jun 2016

Depression reduces COPD maintenance medication adherence in older adults

A recent study in the Annals of the American Thoracic Society found that in a nationally representative sample of Medicare beneficiaries who were newly diagnosed with COPD, adherence to maintenance medications decreased with new episodes of depression.

24 Jun 2016

SLU to conduct human clinical trial of vaccine to protect people from Zika virus

Saint Louis University's vaccine center has been tapped by the National Institutes of Health to conduct a human clinical trial of a vaccine to prevent the Zika virus, which can cause devastating birth defects in babies.

24 Jun 2016

Researchers develop new formulations for topical treatments of oral mucosal conditions

On June 24, 2016, at the 94th General Session & Exhibition of the International Association for Dental Research, researcher W. Peter Holbrook, University of Iceland, will present a study titled "Development of Drugs for Local Treatment of Oral Conditions." The IADR General Session is being held in conjunction with the 3rd Meeting of the IADR Asia Pacific Region and the 35th Annual Meeting of the IADR Korean Division.

24 Jun 2016

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study by Johns Hopkins Medicine researchers.

24 Jun 2016

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

The first global mapping of artemisinin resistance has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa.

24 Jun 2016

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

There is merit in looking at the use of wearable biosensors to detect whether opioid users stay focused on their rehabilitation programs.

23 Jun 2016

Pharmaceutical News

Experimental lipid-lowering drug improves glucose control in diabetic patients

Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Researchers test new drug with potential to reverse or slow progression of asthma

Pain reliever appears to help preserve vision in animal model of retinal degeneration

Cisplatin-based chemotherapy may lead to hearing loss in many testicular cancer survivors

Anti-anxiety medication dampens helping behavior in rats

Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

HDAC inhibitors may help regulate alcoholism-induced anxiety

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

Federal government continues to ban valid scientific research on medicinal use of Cannabis sativa

Oncogene signatures could help design new drug treatments for breast cancer

Novel combination therapy may help provide clinically successful treatment for AD

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

New book highlights advances, challenges in development of nanotheranostics for personalized medicine

Depression reduces COPD maintenance medication adherence in older adults

SLU to conduct human clinical trial of vaccine to protect people from Zika virus

Researchers develop new formulations for topical treatments of oral mucosal conditions

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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