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Organic chemists succeed in synthesizing 3,6-Dihydro-2H-pyran derivatives with high enantiomeric purity

The pyran ring is present in so many useful compounds, such as pharmaceuticals (antibiotics, anti-infectives, cardiovascular agents, neurological modulators, anti-allergic, anti-asthmatic, anti-inflammatory agents, reproductive and genitourinary agents, growth promoters and antidiabetic agents), veterinary products, agrochemicals, toxins, polymers and additives, photosensitizers and photoinitiators, surfactants, food products, dyes and pigments.

28 May 2016

NR supplements can reduce diabetes-related complications in mice

A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System.

27 May 2016

First buprenorphine implant for opioid dependence treatment gets FDA approval

The U.S. Food and Drug Administration today approved Probuphine, the first buprenorphine implant for the maintenance treatment of opioid dependence. Probuphine is designed to provide a constant, low-level dose of buprenorphine for six months in patients who are already stable on low-to-moderate doses of other forms of buprenorphine, as part of a complete treatment program.

27 May 2016

Drexel scientists identify how two new antimalarial drugs work

Drexel University scientists have discovered an unusual mechanism for how two new antimalarial drugs operate: They give the parasite's skin a boost in cholesterol, making it unable to traverse the narrow labyrinths of the human bloodstream.

27 May 2016

Antimuscarinic drugs effective in improving OAB symptoms

In a recent study of patients with overactive bladder (OAB), a 30 mg extended release formulation of propiverine hydrochloride was at least as effective and safe as a 4 mg extended release formulation of tolterodine tartrate.

26 May 2016

Phage therapy in conjunction with antibiotics could help treat dangerous bacterial infection

Yale researchers were fishing for a new weapon against antibiotic resistance and found one floating in a Connecticut pond, they report May 26, 2016 in the journal Scientific Reports.

26 May 2016

New tablet fabrication method can make personalized medicine cheaper, easier

A team of researchers from the National University of Singapore have found a way to make personalized medicine cheaper and easier.

26 May 2016

TSRI scientists discover new method for harnessing venoms for therapeutic use

There are lessons to be learned from venoms. Scorpions, snakes, snails, frogs and other creatures are thought to produce tens or even hundreds of millions of distinct venoms. These venoms have been honed to strike specific targets in the body.

26 May 2016

Combining sonoporation with chemotherapy drug may help improve pancreatic cancer treatment

Researchers at Haukeland University Hospital in Bergen, Norway have combined a laboratory ultrasound technique called "sonoporation" with the commercially-available chemotherapy compound Gemcitabine to increase the porosity of pancreatic cells with microbubbles and to help get the drug into cancer cells where it is needed.

26 May 2016

Pre-treatment with antihistamines may suppress gastrointestinal symptoms of food allergy

Simultaneous pre-treatment with antihistamines that block both the H1 and H4 antihistamine receptors suppressed the gastrointestinal symptoms of food allergy in mice, according to researchers at National Jewish Health.

26 May 2016

Common pain and anti-inflammation drugs may slow cancer growth

Scientists from the Florida campus of The Scripps Research Institute have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests the medication could have the same effect on other types of tumors.

26 May 2016

New data visualization platform identifies shortfalls in vaccine introduction and coverage

As the 69th World Health Assembly discusses progress on the Global Vaccine Action Plan, a new data visualization platform--from the International Vaccine Access Center at the Johns Hopkins Bloomberg School of Public Health--provides stark numbers on where shortfalls exist in vaccine introduction and coverage.

25 May 2016

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

A new study from örebro University, published in Science Signaling today, shows that heart medication reduces the build-up of plaque in the brain's blood vessels in mice. The question is if this is true also in humans? If the answer is yes, it might bring scientists a step closer to developing a medicine against Alzheimer's disease.

25 May 2016

Study finds gap in screening for lipid abnormalities among adults taking antipsychotic medications

Too few adults taking antipsychotic medications are being screened for abnormalities in lipids, which include cholesterol and triglycerides, new research from the University of Colorado Anschutz Medical Campus finds.

25 May 2016

Discrimination linked to lower vaccination rates among racial/ethnic minorities

Yearly flu shots are strongly recommended for adults with certain chronic illnesses, but patients of racial/ethnic minority groups are less likely to receive them.

25 May 2016

Depressive symptoms may affect fertility of women

Women with severe depressive symptoms have a decreased chance of becoming pregnant, while the use of psychotropic medications does not appear to harm fertility, a study by researchers from the Boston University Schools of Public Health and Medicine shows.

25 May 2016

Pharmaceutical News

Organic chemists succeed in synthesizing 3,6-Dihydro-2H-pyran derivatives with high enantiomeric purity

NR supplements can reduce diabetes-related complications in mice

First buprenorphine implant for opioid dependence treatment gets FDA approval

Drexel scientists identify how two new antimalarial drugs work

Antimuscarinic drugs effective in improving OAB symptoms

Phage therapy in conjunction with antibiotics could help treat dangerous bacterial infection

New tablet fabrication method can make personalized medicine cheaper, easier

TSRI scientists discover new method for harnessing venoms for therapeutic use

Combining sonoporation with chemotherapy drug may help improve pancreatic cancer treatment

Pre-treatment with antihistamines may suppress gastrointestinal symptoms of food allergy

Common pain and anti-inflammation drugs may slow cancer growth

New data visualization platform identifies shortfalls in vaccine introduction and coverage

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

Study finds gap in screening for lipid abnormalities among adults taking antipsychotic medications

Discrimination linked to lower vaccination rates among racial/ethnic minorities

Depressive symptoms may affect fertility of women

Study assesses trends in antidepressant prescribing for depression

Antidote-resistant overdose patients may have received synthetic opioid W-18, suspects anesthesiologist

Novel strategy to predict antigenic evolution of circulating influenza viruses

Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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