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Scientists streamline total synthesis of uncialamycin drug

A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin.

23 Jun 2016

Study finds dramatic increase in nonmedical use of prescription opioids in the U.S.

Nonmedical use of prescription opioids more than doubled among adults in the United States from 2001-2002 to 2012-2013, based on a study from the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health. Nearly 10 million Americans, or 4.1 percent of the adult population, used opioid medications in 2012-2013 a class of drugs that includes OxyContin and Vicodin, without a prescription or not as prescribed (in greater amounts, more often, or longer than prescribed) in the past year.

23 Jun 2016

Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Researchers have identified a gene variant which explains why some patients with Parkinson's Disease respond well to drug treatment and other do not.

23 Jun 2016

Long-term suppression of neurotransmitter acetylcholine may lead to dementia-like changes in the brain

A new study from Western University is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk of developing dementia later in life.

23 Jun 2016

JAMA edition provides summary of FSMB policy recommendations about marijuana in patient care

The Journal of the American Medical Association has published in its online edition a summary of new policy adopted by the Federation of State Medical Boards that provides recommendations about marijuana in patient care and a cautionary note advising actively licensed physicians to abstain from using marijuana while practicing medicine.

23 Jun 2016

New magnetically controlled drug safe, effective in dissolving blood clots

Critical conditions associated with the blockage of blood vessels are one of the primary health concerns worldwide.

22 Jun 2016

Paclitaxel drug may promote cancer spread at low doses

New research indicates that paclitaxel, which is the most commonly used chemotherapy for breast cancer, suppresses tumors when given at a certain dosage, but at low doses, it actually promotes cancer spread to the liver.

22 Jun 2016

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

A UCLA-led study estimates that almost 28,500 deaths could be prevented each year in the U.S. through use of a new FDA-approved class of cardiovascular medication that helps reduce mortality in patients diagnosed with heart failure and reduced ejection fraction, the percentage of blood pumped from the heart with each contraction.

22 Jun 2016

Marketing authorisation for Penthrox handheld inhaler issued in France

Mundipharma International Limited today announced that Penthrox has been granted marketing authorisation in France for the emergency relief of moderate to severe pain in conscious adult patients with trauma and associated pain.

22 Jun 2016

Women need more propofol to stay sedated during oral surgery

Anesthesia Progress – The stress that oral surgery patients experience during a procedure can cause elevated heart rates and blood pressure during operations.

22 Jun 2016

Microbial community less stable and less diverse in antibiotic-treated children

The DIABIMMUNE project followed the development of 39 Finnish infants from birth to the age of three. Half of the children received 9-15 antibiotic treatments during the research period, and the other half did not receive any such treatments.

22 Jun 2016

ACP provides physician perspective on rising prescription drug prices

The American College of Physicians today provided physician perspective on the escalating cost of prescription drugs, the impact of the costs on internal medicine physicians and their patients, and support for the intent of the bipartisan Creating and Restoring Equal Access to Equivalent Samples (CREATES) Act of 2016 to reduce anti-competitive practices.

22 Jun 2016

New study reveals conversion of oral cannabidiol to THC by acidic fluids in the stomach

A new study demonstrating the conversion of oral cannabidiol (CBD) to the psychoactive component tetrahydrocannabinol (THC) in the presence of gastric fluids could explain why children given CBD to treat epilepsy had an unexpectedly high rate of adverse effects such as sleepiness and fatigue.

22 Jun 2016

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Mapping the molecular structure where medicine goes to work is a crucial step toward drug discovery against deadly diseases.

21 Jun 2016

Study shows Alzheimer's disease can lead to diabetes

Drugs used to treat diabetes could also be used to treat Alzheimer's disease, and vice versa, according to new research from the University of Aberdeen.

21 Jun 2016

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

A new meta-analysis published in Clinical Nutrition found that cardiac surgery patients who received omega-3 polyunsaturated fatty acids (compared to placebo) in advance of surgery experienced reduced postoperative cardiac arrhythmias and significantly reduced the length of hospital stay by up to 2.4 days. The results are based on 11 RCT's with 1038 patients.

21 Jun 2016

Unmanned drones could be economical to deliver vaccines quickly in developing countries

Using unmanned drones to deliver vaccines in low- and middle-income countries may save money and improve vaccination rates, new research led by the Johns Hopkins Bloomberg School of Public Health and the Pittsburgh Supercomputing Center suggests.

21 Jun 2016

New Aspirin-Guide mobile app helps clinicians and patients make informed decisions about aspirin use

Low dose aspirin is recommended by clinicians as a preventive measure for patients who have already had a heart attack or stroke, but the risk of taking low-dose aspirin to prevent or delay a first heart attack or stroke is less clear, as the benefit for reducing the risk of cardiovascular disease (CVD) must be balanced with the increased risk of gastrointestinal or other bleeding.

21 Jun 2016

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Mayo Clinic is highlighting the potential merits of using precision medicine in prescribing antidepressants. Details appear in the current issue of Mayo Clinic Proceedings.

21 Jun 2016

Potential therapeutic approaches to combat chronic myeloid leukemia

Chronic myeloid leukemia (CML) develops through chromosomal alterations in blood-forming cells of the bone marrow and usually occurs in older persons. Around 20 percent of adults diagnosed with leukemia suffer from this type of blood cancer.

21 Jun 2016

Pharmaceutical News

Scientists streamline total synthesis of uncialamycin drug

Study finds dramatic increase in nonmedical use of prescription opioids in the U.S.

Two gene variants provide clue to why some patients with PD respond well to rasagiline drug

Long-term suppression of neurotransmitter acetylcholine may lead to dementia-like changes in the brain

JAMA edition provides summary of FSMB policy recommendations about marijuana in patient care

New magnetically controlled drug safe, effective in dissolving blood clots

Paclitaxel drug may promote cancer spread at low doses

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

Marketing authorisation for Penthrox handheld inhaler issued in France

Women need more propofol to stay sedated during oral surgery

Microbial community less stable and less diverse in antibiotic-treated children

ACP provides physician perspective on rising prescription drug prices

New study reveals conversion of oral cannabidiol to THC by acidic fluids in the stomach

Molecular map of transporter proteins could be vital step toward drug discovery against zinc-related diseases

Study shows Alzheimer's disease can lead to diabetes

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

Unmanned drones could be economical to deliver vaccines quickly in developing countries

New Aspirin-Guide mobile app helps clinicians and patients make informed decisions about aspirin use

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Potential therapeutic approaches to combat chronic myeloid leukemia

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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