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EAD therapy can shrink size of triple-negative breast cancer tumors in mice

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.

20 May 2016

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.

19 May 2016

Understanding potential of illicit drug ketamine in treating depression

Advancing the understanding and treatment of psychiatric disorders is a principal goal of neuroscientists. As mental disorders are the leading cause of disabilities worldwide, it is concerning that there are few effective therapeutics on the market due to the lack of knowledge regarding pathophysiology.

19 May 2016

New drug that combines methicillin with polymer BPEI can combat MRSA

A University of Oklahoma team of chemists has developed a new antibiotic formulation to fight the sometimes deadly staph infection caused by methicillin-resistant S. aureus or MRSA and other antibiotic-resistant infectious bacteria.

19 May 2016

Action on Hearing Loss funds new study to discover ways of preventing deafness caused by cancer drug

A widely used anti-cancer drug, cisplatin, can cause permanent and severe hearing loss, having a devastating impact on the quality of life for cancer survivors.

19 May 2016

New Quick Reference Guide set to improve antibiotic prescribing

A Tasmanian initiative to provide a ‘Quick Reference Guide’ to antibiotic prescribing in the community has been embraced by general practitioners (GPs) and is set to improve prescribing, delegates at the National Medicines Symposium in Canberra have heard.

19 May 2016

UK-wide study reveals AOD prescription rates for women decrease in last 10 years

A UK-wide study looking at the prescribing of anti-osteoporotic drugs (AOD) to people aged 50 years or above has found that, since 2006, AOD prescription rates for women have decreased and rates for men have levelled off, despite a growing elderly population and associated fracture risks.

19 May 2016

Ramizol drug shows promise in treatment of Clostridium difficile infections

A scientific paper released today in the Journal of Antibiotics presents the pre-clinical development of Ramizol, a first generation drug belonging to a new class of styrylbenzene antibiotics with a novel mechanism of action.

19 May 2016

Flavopiridol drug could be effective strategy to impair brain cancer growth

Glioblastoma, the most common form of brain cancer is a deadly disease for which at present there is no cure. Now, researchers have published research results that show how repurposing the old drug flavopiridol could be an effective strategy to cut short sugar availability and impair cancer growth.

19 May 2016

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

For the first time, researchers were able to demonstrate that children diagnosed with sickle cell disease showed improvement in lung function after treatment with hydroxyurea, a treatment that is underused despite its demonstrated benefits.

19 May 2016

ICS users may be at greater risk for nontuberculous mycobacteria pulmonary disease

Patients with obstructive lung disease who take inhaled corticosteroids (ICS) may be at greater risk for nontuberculous mycobacteria pulmonary disease (NTM PD), according to new research presented at the ATS 2016 International Conference.

19 May 2016

Mouse model of depression can help better understand how ketamine functions

New research demonstrates the effectiveness of ketamine to treat depression in a mouse model of the disease and brings together two hypotheses for the cause of depression.

19 May 2016

Tecentriq drug gets FDA approval to treat urothelial carcinoma

The U.S. Food and Drug Administration today approved Tecentriq (atezolizumab) to treat the most common type of bladder cancer, called urothelial carcinoma. This is the first product in its class (PD-1/PD-L1 inhibitors) approved to treat this type of cancer.

19 May 2016

Taking pregabalin drug during pregnancy could lead to major birth defects

A drug commonly used to treat pain, epilepsy, anxiety and other brain health disorders may be associated with an increased risk of major birth defects, according to a study published in the May 18, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 May 2016

Effective chemotherapeutic drug may induce permanent hearing loss in Cockayne syndrome individuals

The chemotherapy drug cisplatin can kill cancer, but it can also cause permanent hearing loss.

19 May 2016

Easy, immediate access to effective antidotes could help reduce deaths from opioid overdose

Over the past 15 years, deaths caused by heroin and prescription opioid overdoses have quadrupled despite the existence of a highly effective antidote. The cover story in Chemical & Engineering News, the weekly news magazine of the American Chemical Society, explores what it might take to turn the tide.

19 May 2016

Neurotoxic effects of chemotherapy may impair cognitive function in young ALL patients

The neurotoxic effects of chemotherapeutic drugs on the developing brains of young patients with acute lymphoblastic leukemia (ALL) may impair their cognitive functioning by disrupting the formation of neural networks that connect brain regions and transfer information.

19 May 2016

Pharmaceutical News

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

Understanding potential of illicit drug ketamine in treating depression

New drug that combines methicillin with polymer BPEI can combat MRSA

Action on Hearing Loss funds new study to discover ways of preventing deafness caused by cancer drug

New Quick Reference Guide set to improve antibiotic prescribing

UK-wide study reveals AOD prescription rates for women decrease in last 10 years

Ramizol drug shows promise in treatment of Clostridium difficile infections

Flavopiridol drug could be effective strategy to impair brain cancer growth

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

ICS users may be at greater risk for nontuberculous mycobacteria pulmonary disease

Mouse model of depression can help better understand how ketamine functions

Tecentriq drug gets FDA approval to treat urothelial carcinoma

Taking pregabalin drug during pregnancy could lead to major birth defects

Effective chemotherapeutic drug may induce permanent hearing loss in Cockayne syndrome individuals

Easy, immediate access to effective antidotes could help reduce deaths from opioid overdose

Neurotoxic effects of chemotherapy may impair cognitive function in young ALL patients

Melatonin can be of great value for elderly people suffering from hypertension

Take complementary medicines with care

Prenatal exposure to SSRIs linked to lower birth weight, gestational length

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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